Custom Peptides
Cayman Chemical PhelodendrInchlorIde 10mg
An alkaloid; inhibits AChE activity (IC50 = 36.51 µM and scavenges ABTS radicals in cell-free assays from 12.5-100 µM; induces apoptosis in PANC-1 pancreatic cancer cells and reduces tumor growth in a PANC-1 mouse xenograft model; inhibits the GVH reaction in irradiated mice receiving splenocyte grafts at 20 mg/kg
Cayman Chemical -Glu-AlatrIfluoroACTAte500mg
A dipeptide; has been found in P. roqueforti; has been found in ripened Gouda, goat, and Milner cheeses; a positive allosteric modulator of CaSR (EC50 = 4.8 µM in CaSR-expressing HEK293 cells); induces glutathionuria in mice at 4 mmol/kg; plasma levels are increased in malnourished neonatal mice; increased serum levels are positively associated with an increased risk of chronic kidney disease
Cayman Chemical 8-Gernyloxypsoralen 10mg
A prenylated furanocoumarin with diverse biological activities; inhibits CYP3A4 and BACE1 (IC50s = 3.93 and 20.4 µM, respectively); inhibits TPA-induced Epstein-Barr virus activation in infected Raji cells, TPA-induced superoxide generation in HL-60 cells, and LPS- and IFN-γ-induced NO generation in RAW 264.7 macrophages at 50 µM
Cayman Chemical Periplogenin 10MG
A cardenolide and an active metabolite of periplocin with diverse biological activities; reduces the activity of porcine Na+/K+ ATPase at 0.3 or 0.6 µM; induces apoptosis in U937 and PC3 prostate cancer cells, as well as inhibits the proliferation of these cells (EC50s = 1.41 and 1.2 µM, respectively) at 0.1 or 0.2 µM; increases ROS production and induces necroptosis in HaCaT keratinocytes at 2 UG/ml; reduces EAr thickness in a mouse model of TPA-induced psoriasis
Cayman Chemical -CloprostenolsodIum salt 10mg
(+)-Cloprostenol (sodium salt) is a more water soluble, crystalline form of (+)-cloprostenol.
Cayman Chemical 4mthylN NDImthylcathInon 10mg
An analytical reference standard categorized as a cathinone; intended for research and forensic applications
Bachem (D-Ala2)-Gastric Inhibitory Polypeptide (human) Trifluoroacetate
(D-Ala2)-Gastric Inhibitory Polypeptide (human) Trifluoroacetate, H-Tyr-D-Ala-Glu-Gly-Thr-Phe-Ile-Ser-Asp-Tyr-Ser-Ile-Ala-Met-Asp-Lys-Ile-His-Gln-Gln-Asp-Phe-Val-Asn-Trp-Leu-Leu-Ala-Gln-Lys-Gly-Lys-Lys-Asn-Asp-Trp-Lys-His-Asn-Ile-Thr-Gln-OH, 444073-04-5, C226H338N60O66S, Mr 4983.53, 0.5mg. (D-Ala2)-GIP (human), [DAla2] Gastric Inhibitory Peptide (GIP), human. GIP receptor agonist.
Cayman Chemical 3 4DImethylethcathInonhyd 10mg
A substituted cathinone with potential for abuse; intended for forensic and research applications
Cayman Chemical 2EthylethcathInonhydrochl 10mg
A substituted cathinone with potential for abuse; intended for forensic and research applications
Cayman Chemical SucInIMDyl 4formylbenzoat 10mg
A heterobifunctional building block; has been used in the conjugation of oligonucleotides to antibodies for protein detection, as well as in the synthesis of fluorescent BODIPY-etoposide
Cayman Chemical TFB-TBOAhydrate 10mg
An inhibitor of EAAT1 and EAAT2 (IC50s = 22 and 17 nM for EAAT1 and EAAT2, respectively); selective for EAAT1 and EAAT2 over EAAT3 (IC50 = 300 nM), as well as a variety of neurotransmitter transporters and receptors at 10 µM; inhibits L-glutamate- and L-aspartate-induced currents in X. laevis oocytes at 10 µM; induces convulsions in mice at 0.2 UG/animal
Cayman Chemical CagrIlIntIdeacetate 10mg
An amylin and calcitonin receptor agonist; binds to the AMY3 and calcitonin receptors (IC50s = 170 and 223 pM, respectively, for the human receptors); activates human AMY3 and calcitonin receptors in reporter assays (EC50s = 49 and 62 pM, respectively); increases cAMP accumulation in COS-1 cells expressing AMY1, AMY3, or calcitonin receptors (EC50s = 79.43, 114.82, and 43.65 nM, respectively); has a low propensity for inducing amyloid fibril formation with a lag time of 45 hours in a thioflavin T assay at 250 µM; reduces food intake in rats for at least 48 hours after a single dose of 3 or 30 nmol/kg; reduces body weight, food intake, and fat mass in a mouse model of diet-induced obesity at 100 nmol/kg
Cayman Chemical Fexinidazole 10MG
Fexinidazole is an antiparasitic agent; active against 15 strains of T. brucei, including T. b. rhodesiense, T. b. brucei, and T. b. gambiense (IC50s = 0.95-3.31 µM); inhibits the growth of L. donovani at the promastigote and axenic amastigote stages (EC50s = 5.6 and 2.8 µM, respectively) ; parasitic burden and increases survival in a mouse model of infection with benznidazole-susceptible, -partially resistant, or -resistant T. cruzi at doses ranging from 50-300 mg/kg per day
Cayman Chemical 9keto FlupROSnl Isopropyl 10mg
An ester derivative of fluprostenol; a potential prodrug to 9-keto fluprostenol; a potential metabolite of fluprostenol isopropyl ester (travoprost)
Cayman Chemical SItamaquIntosylate 10mg
An antileishmanial agent; active against L. donovani, L. infantum, L. mexicana, L. braziliensis, and L. tropica (EC50s = 9.5-19.8 µM); inhibits SDH in a cell-free assay (10-200 µM); increases intracellular ROS levels, decreases intracellular ATP levels, and induces phosphatidylserine externalization, chromatin fragmentation, and depolarization of the mitochondrial membrane potential in L. donovani promastigotes