Custom Peptides
Cayman Chemical CapsIconIate 10mg
A coniferyl ester that acts as a partial agonist of TRPV1 (EC50 = 3.2 µM), eliciting only 20% of the maximum response induced by capsaicin
Cayman Chemical 4hydropRoxy CyclophsphaMD 10mg
An activated analog of cyclophosphamide; crosslinks DNA and induces T cell apoptosis independent of death receptor activation but activates mitochondrial death pathways through the production of ROS at 1 and 3 UG/ml; reduces tumor growth in an MX-1 breast cancer mouse xenograft model at 0.05, 0.1, and 0.15 mmol/kg
Cayman Chemical nlfInavIrmesylate 10mg
An orally bioavailable inhibitor of the HIV-1 protease (Ki =2 nM) that is used in combination with HIV reverse transcriptase inhibitors for the treatment of HIV infection
Cayman Chemical CalcInurIn SubstrATtrIflu 10mg
A synthetic peptide substrate; can be used as a substrate to quantify calcineurin activity
Cayman Chemical C15 CeramIded18 115 0 10mg
A naturally occurring ceramide; has been found in L. nidifica and A. glomerata extracts, human erythrocytes, and the stratum corneum of P. domesticus
Cayman Chemical DInhydrogalactItol 10mg
A DNA alkylating agent; induces N7-alkylation of guanine and interstrand DNA cross-links in vitro; halts the cell cycle at the G2/M phase in U-251MG and T98G cells at 0.5-8 µM; decreases the migration and invasion of U251 cells and tube formation of HUVECs at 12.5 UG/ml; increases survival in a U-251MG mouse xenograft model when administered in combination with temozolomide
Cayman Chemical 1 2DIhexadecylsnglycero3 10mg
A phospholipid; commonly used in the generation of liposomes and artificial membranes to study membrane dynamics
Cayman Chemical ZInquIn ethyl ester 10mg
A cell-permeable, quinolone-based fluorescent probe used as a zinc indicator (excitation 368 nm, emission 490 nm); used to monitor intracellular zinc fluxes associated with apoptosis
Cayman Chemical GlucosdePNdent Insulnotro 10mg
A peptide incretin hormone; inhibits histamine, pentagastrin, and insulin-induced gastric acid and pepsin secretion, increases glucose-induced insulin release, and stimulates gastric emptying in rats
Cayman Chemical PPACKtrIfluoroacetAT salt 10mg
A synthetic peptide derivative that irreversibly and specifically inhibits thrombin-mediated platelet activation by binding with high affinity to the active site of thrombin (Ki = 0.24 nM); used as an anticoagulant (100 μM)
Cayman Chemical Benoxaprofen 10mg
An NSAID; inhibits PGE2 and LTC4 production in A23187-stimulated isolated mouse peritoneal macrophages at 100 µM; inhibits serum-induced chemotaxis of isolated rat peritoneal leukocytes at 25 and 50 UG/ml; induces hemolysis in isolated human erythrocytes and histamine release in isolated rat peritoneal mast cells in a light-dependent manner at 10 µM; reduces carrageenan-induced paw edema and yeast-induced fever in rats and acetic acid-induced writhing in mice
Cayman Chemical Gernylgernylaceton 10mg
An inducer of Hsp expression that increases Hsp70, Hsp22, Hsp27, Hsp90, and Hsp105 levels in various cells and tissues; orally bioavailable and has diverse effects in vivo, including hepatoprotective, neuroprotective, and antiulcerative effects
Cayman Chemical Phylnthn 10mg
A bioactive lignan component of P. amarus with antioxidative and hepatoprotective properties; scavenges DPPH radicals (IC50 = 7.4 µM) and alleviates carbon tetrachloride-induced lipid peroxidation and cytotoxicity in a human hepatoma HepG2 cell line
Cayman Chemical L-CarnItIn-d9chlorIde 10mg
An internal standard for the quantification of L-carnitine by GC- or LC-MS