Custom Peptides
Cayman Chemical BupIvacaIn-d9 10mg
An internal standard for the quantification of bupivacaine by GC- or LC-MS
Cayman Chemical 1 3 7TrImethylurIc AcIdd9 10mg
An internal standard for the quantification of 1,3,7-trimethyluric acid by GC- or LC-MS
Cayman Chemical acetylBoswellic ACD 10mg
A non-reducing inhibitor of 5-LO that shows selectivity for 5-LO over 12-LO or COX; inhibits topoisomerase II activity and arrests cell cycling or induces apoptosis in cancer cells
Cayman Chemical TetrahydrocurcumIn 10mg
A metabolite of curcumin with diverse biological activities; scavenges DPPH radicals in a cell-free assay (EC50 = 16.8 μM); inhibits LPS-induced increases in iNOS and COX-2 expression in RAW 264.7 cells at 50 µM; inhibits LPS-induced increases in TNF-α release at 100 µM; inhibits LPS-induced increases in NO production and IL-6 levels in a concentration-dependent manner; reduces carrageenan-induced paw edema in rats (ED50 = 20 mg/kg); reduces the formation of neocapillaries and decreases microvascular density as well as VEGF, VEGFR2, and HIF-1α expression in a CaSki cervical cancer nude mouse xenograft model at 100, 300, and 500 mg/kg
Cayman Chemical JWH 018 2naphthylN 1 2dI 10mg
Differs from JWH 018 structurally by having a 1,2-dimethylpropyl chain, rather than a pentyl chain, extending from the indole group and the naphthyl moiety attached at its 2 position
Cayman Chemical B-HT 920hydrochlorIde 10mg
A potent agonist of D2 receptors (Ki = 5.8 nM); has neuroprotective and regenerative effects in animal models of Parkinson’s disease
Cayman Chemical MecamylamInhydrochlorIde 10mg
A noncompetitive nicotinic acetylcholine receptor antagonist with preferential activity at the α3β4 subtype (IC50 = 90-640 nM) compared to α4β2, α3β2, and α7 subtypes (IC50s range from 1-7 μM)
Cayman Chemical VecuronIumbromIde 10mg
A non-depolarizing muscle relaxant that competitively blocks cholinergic receptors at the motor end plate of the neuromuscular junction, inducing temporary paralysis
Cayman Chemical 3 4MethylendIoxy PV9hydro 10mg
A cathinone whose physiological and toxicological properties are not known
Cayman Chemical 4 4-DIcynobenzhydrol 10mg
An analytical reference standard that is a metabolite of letrozole; has been used as a marker of letrozole use in athletes; intended for research and forensic applications
Cayman Chemical ThIomuscImol 10mg
A GABAA receptor agonist (IC50 = 19 nM) that has been used as a photoaffinity label for the purification and identification of GABA binding sites within the GABAA receptor complex
Cayman Chemical 8-PrenylnarngenIn 10mg
A prenylflavonoid with potent estrogenic activity that inhibits both ERα and ERβ (IC50s = 57 and 68 nM, respectively); effective in vivo, suppressing bone loss and temperature changes in rat models of osteoporosis and postmenopausal hot flashes
Cayman Chemical RoflumIlast 10mg
A PDE4 inhibitor (IC50 = 0.8 nM); selective for PDE4 over PDE1, -2, -3, and -5 (IC50s = >10, >10, >10, and 8 µM, respectively); inhibits fMLP-induced LTB4 production in isolated human neutrophils (IC50 = 2 nM); reduces the proliferation of anti-CD3 and anti-CD28-stimulated isolated human CD4+ T cells (IC30 = 7 nM); prevents pulmonary inflammatory cell infiltration and emphysema in mice exposed to cigarette smoke at 5 mg/kg