Custom Peptides
Cayman Chemical Corynoxen 10mg
An alkaloid with diverse biological activities; inhibits LPS-induced production of NO in primary rat microglia (IC50 = 15.7 µM); inhibits PDGF-BB-induced ERK1/2 activation in, and proliferation of, rat aortic VSMCs from 5-50 µM; inhibits compound 48/80-induced histamine release from LAD 2 mast cells from 25-200 µM; reduces compound 48/80-induced local anaphylaxis and mast cell degranulation in mouse hind paws at 0.5, 2.5, and 5 mg/kg; reduces methamphetamine-induced hyperlocomotion in mice at 30 and 100 mg/kg
Cayman Chemical S-Lnsoprazole 10mg
A proton pump inhibitor and pure enantiomer of lansoprazole; inhibits H+/K+-stimulated ATPase pumps in parietal cells (IC50 = 5.2 µM); inhibits acid formation in isolated canine parietal cells (IC50 = 82 µM)
Cayman Chemical 4EthylethcathInonhydrochl 10mg
A substituted cathinone with potential for abuse; intended for forensic applications
Cayman Chemical KIntensInhumntrIfluoro 10mg
A neurotensin ligand; binds to neurotensin receptors in HT-29 cells and mouse brain (Kis = 1,396 and 149.6 nM, respectively) but does not induce the accumulation of intracellular calcium in HT-29 cells (EC50 = >10,000 nM); induces histamine release in isolated rat peritoneal mast cells (EC50 = ~10 µM); induces vascular permeability in rats
Cayman Chemical 13Z 16ZDocosadIenoIc AcId 10mg
A natural ω-6 PUFA; an agonist of FFAR4 (GPR120) that strongly inhibits the secretion of ghrelin by isolated mouse gastric cells
Cayman Chemical PalmItoylLcarnItInchLRI 10mg
A long-chain acylcarnitine; delivers palmitate into the mitochondria for fatty acid oxidation and energy production; inhibits lecithin:cholesterol acyltransferase activity in isolated rat plasma at 500 µM; serum and hepatic levels are increased in mice during cold exposure; protects against age-induced cold sensitivity in mice
Cayman Chemical 4-palmItamIdo TEMPO 10mg
A lipid-soluble spin label; incorporates into vesicles and cell membranes; has been used to study the entrapment of molecules within phosphatidylcholine vesicles
Cayman Chemical Sartrypyron B 10mg
A fungal metabolite; inhibits the growth of MCF-7, H460, and A375 cancer cells (GI50s = 17.8, 20.5, and 25 µM, respectively)
Cayman Chemical Acontum carmchal Dlsoln 10mg
A diterpene alkaloid with diverse biological activities; inhibits binding of α-bungarotoxin to rat neuronal α7 nAChRs (IC50 = 19 µM); repellent against adult red flour beetles in a filter paper assay at 3 mg/ml; lowers systolic blood pressure in a rat model of left renal artery ligation-induced hypertension at 75 mg/kg
Cayman Chemical PunIca grnatum PunIcaln 10mg
An ellagitannin with diverse biological activities; inhibits the SARS-CoV-2 spike RBD and ACE2 interaction (IC50 = 0.14 mg/ml); an inhibitor of carbonic anhydrase (IC50 = 1 µM); scavenges DPPH radicals and superoxide anions, as well as inhibits lipid peroxidation, in cell-free assays in a concentration-dependent manner; increases SOD and GPX activities, and decreases MDA levels, in the intestine in a mouse model of oxidative stress at 10 mg/kg per day
Cayman Chemical JWH 122 7mthylnaphthyl 10mg
Differs from JWH 122 in that the methyl group is attached to the naphthyl rings at the 7, rather than the 4, position
Cayman Chemical C4 CeramIded18 14 0 10mg
A bioactive sphingolipid; inhibits IL-4 production by 16% in PMA-stimulated EL4 T cells at 10 μM; cytotoxic to SK-BR-3 and MCF-7/Adr breast cancer cells (IC50s = 15.9 and 19.9 μM, respectively); increases maturation and stability of F508del-CFTR proteins, enhances cAMP-activated chloride secretion, and suppresses secretion of IL-8 in primary epithelial cells isolated from patients with cystic fibrosis