Custom Peptides
Cayman Chemical HomovnIlIc AcId sulfateso 10mg
A phenol found in olive oil and a dopamine metabolite; a component of LDL in humans that consume olive oil; levels are increased in response to acute renal injury in humans and rats; has been used as a biomarker for EArly detection of kidney disease in pediatric nephrology
Cayman Chemical 4MethyLMbelIferyl DGala 10mg
A fluorogenic substrate used to quantify GALNS activity; is cleaved by GALNS to release the fluorescent moiety 4-MU; ex = 320 and 360 nm at low (1.97-6.72) and high (7.12-10.3) pH, respectively; em = 445-455 nm, increasing as pH decreases; used to detect Morquio disease type A in an assay using a very small blood volume
Cayman Chemical MesorIdazIn 10mg
An active metabolite of thioridazine; formed via sulfoxidation of thioridazine by CYP2D6 in human liver microsomes; binds to histamine H1, dopamine D2, muscarinic acetylcholine, and α1- and α2-adrenergic receptors (Kds = 1.8, 19, 69, 2, and 1,600 nM, respectively); prevents mescaline-induced hyperactivity in mice at 10, 30, and 45 mg/kg
Cayman Chemical AlflutInIbmesylate 10mg
An inhibitor of mutant EGFRs; selective for EGFRL858R, EGFRG719X, EGFRL858R, EGFRL861A, and EGFRT790M mutant EGFRs over wild-type EGFR; reduces tumor growth in an EGFRL858R and EGFRT790M-expressing LU1868 NSCLC PDX mouse model at 10 and 30 mg/kg
Cayman Chemical 2DeoxycytIdIn 5dIphospha 10mg
A nucleotide diphosphate for various biochemical research applications including studies of DNA synthesis; substrate for nucleoside diphosphate kinases
Cayman Chemical ZapnometInIb 10mg
A MEK inhibitor (IC50 = 5.73 nM) and an active metabolite of CI-1040; reduces viral titers in A549 and MDCK cells infected with influenza A (EC50s = 6.356 and 4.498 µM, respectively); increases survival in H1N1pdm09 influenza A-infected mice at 50 mg/kg per day
Cayman Chemical Galantamine 10mg
An alkaloid with AChE inhibitory and nAChR potentiating activities; selectively inhibits AChE over BChE (IC50s = 636 and 8,404 nM, respectively); potentiates ACh-induced currents in HEK293 cells expressing human α4β2 subunit-containing nAChRs at 0.5 µM; decreases escape latency and path length in the Morris water maze in the APP23 transgenic mouse model of Alzheimer’s disease at 1.3 mg/kg per day
Cayman Chemical 1 3DIpalmItol2ElaIdol Gl 10mg
A triacylglycerol; has been synthesized as a partially hydrogenated confectionery fat; when used as 10% of the fat component in cocoa butter, it promotes the conversion of low-melting polymorphic forms of cocoa butter-PEP mixtures to high-melting polymorphic forms
Cayman Chemical ImIpenmhydrate 10mg
An intravenous β-lactam antibiotic effective against a wide range of Gram-positive and Gram-negative bacteria (MICs range from 0.5-2 UG/ml for E. cloacae and P. aeruginosa), including several multi-drug resistant bacterial species
Cayman Chemical Latnoprost Lactol 10mg
Latanoprost is an F-series prostaglandin analog which has been approved for use as an ocular hypotensive drug. Latanoprost lactol is an intermediate in the synthesis of latanoprost. Latanoprost lactol can be converted to the free acid of latanoprost by Wittig reaction with commercially available reagents.
Cayman Chemical PyrrolIdIn RIcInoleamIde 10mg
A derivative of the amide of ricinoleic acid that shows potent antiproliferative activity against an array of cancer cell lines
Cayman Chemical 15-keto Latnoprost 10mg
An active metabolite of latanoprost; intraocular administration reduces intraocular pressure in cynomolgus monkeys at 1 UG/eye; reduces pupillary diameter in cats when administered topically at 5 UG/eye
Cayman Chemical Pyrrophenon 10mg
Reversible, selective inhibitor of cPLA2 with an IC50 value of 4.2 nM in enzyme assays; potently blocks the release of AA and the production of PGE2 and LTC4 in cells (IC50 = 24, 25, and 14 nM, respectively)