Custom Peptides
Cayman Chemical ZolIflodacIn 10mg
A fluoroquinolone antibiotic; inhibits bacterial DNA gyrase supercoiling activity and topoisomerase IV DNA decatenation; active against 250 clinical isolates of N. gonorrhoeae, including XDR and MDR strains (MICs = 0.004-0.25 UG/ml); active against MRSA clinical isolates, as well as 10 clinical isolates EAch of C. trachomatis and C. pneumoniae (MIC50s = 0.125 and 0.5 UG/ml, respectively)
Cayman Chemical DeslorelInacetate 10mg
A peptide agonist of GnRH; binds to GnRHR (Ki = 0.1 nM); decreases testicular volume, semen volume, sperm motility, and total sperm count, as well as increases the percentage of abnormal sperm, in dogs via a subcutaneous implant at 3, 6, and 12 mg per animal; decreases disease severity and plasma levels of estradiol, 17-hydroxyprogesterone, and androstenedione in ferrets with ACD at 3 mg/implant per animal; suppresses ovulation and estrus in cats at 4.7 mg/implant per animal
Cayman Chemical Aunt fumatuus Nautn 10mg
A flavanone; reduces airway sensitivity, eosinophil counts and IL-4 levels in BALF, and serum IgE levels in a mouse model of ovalbumin-induced airway inflammation at 10 mg/kg; decreases immobility in the forced swim test and latency to feeding in the novelty-suppressed feeding test, indicating antidepressant-like activity in mice
Cayman Chemical MDDMAhydrochlorIde 10mg
A centrally active substituted methylenedioxyphenethylamine that is structurally similar to 3,4-MDMA; intended for research and forensic applications
Cayman Chemical 1 2DIphytnoylsnglycero3 10mg
A phospholipid; has been used in the creation of lipid bilayer membranes; has been used, in combination with LPS, to form the outer leaflet of a tethered bilayer lipid membrane as a model of a Gram-negative bacterial membrane
Cayman Chemical CucurbItacIn E 10mg
A natural triterpene; reduces MPP+-induced death of neuronal PC12 cells through inhibition of autophagy in vitro; inhibits growth of T24 bladder, MDA-MB-468 and MCF-7 breast, PC3 prostate, and colorectal cancer cell lines (IC50s = 50-1,000 nM) through induction of G2/M arrest and apoptosis; increases bilirubin binding to HSA in human plasma in a dose-dependent manner; inhibits depolymerization of actin filaments isolated from rabbit skeletal muscle actin and in HeLa cells
Cayman Chemical NMethylNnItrosopIperazIn 10mg
A potential impurity in various pharmaceutical preparations
Cayman Chemical N-MethylnucIferInIodIde 10mg
An aporphine alkaloid with diverse biological activities; scavenges DPPH radicals (IC50 = 711.76 UG/ml); inhibits α-glucosidase and α-amylase (IC50s = 2,627.78 and 1,818.18 UG/ml, respectively); reduces LPS-induced NO production in BV-2 microglia at 20 µM
Cayman Chemical RhodIola rosea RosavIn 10mg
A diglycoside with diverse biological activities; scavenges DPPH radicals in a cell-free assay (IC50 = 5.86 UG/ml); inhibits the proliferation of NCI H69, NCI H526, and NCI H446 SCLC cells at 5-100 µM; inhibits concanavalin A- or anti-CD3 and anti-CD28 antibody-induced growth of Jurkat T cells (IC50s = 80 and 74 µM, respectively) and reduces TRAIL levels in isolated mouse splenic T cells at 0.5, 5, and 50 µM; reduces ferroptosis-related mitochondrial changes and increased levels of 4-HNE and MDA in type II alveolar epithelial cells, as well as reduces lung tissue iron levels, in a rat model of intratracheal PM2.5-induced lung injury at 100 µM
Cayman Chemical Mastoparn 7trIfluoroACTAt 10mg
A G protein-activating peptide; decreases the affinity of ACh to porcine brain mAChRs at 30 µM; induces activation of Gαo in, and increases dendritic spine density of, primary rat hippocampal neurons at 1 µM; induces contractions in isolated perfused rat tail arteries (EC50 = 44.1 nM); immunization with a vaccine against cocaine in combination with mastoparan 7 as an adjuvant increases hapten-specific serum IgG levels and decreases cocaine-induced locomotion in mice
Cayman Chemical 2MethylamIno1phenylbutn 10mg
A methamphetamine analog with structural similarity to 2-ethylamino-1-phenylbutane; intended for forensic and research applications
Cayman Chemical 4FluoromethamphetamInhydr 10mg
A stimulant drug related to methamphetamine and 4-fluoroamphetamine that has been identified as a component of designer drugs sold as “legal high” replacements for restricted substances; intended for use as a standard for the forensic analysis of samples that may contain this compound
Cayman Chemical LInoleoyl GlycIn 10mg
An endogenous homolog of arachidonyl glycine that inhibits AEA hydrolysis in FAAH-containing N18TG2 cell membranes with an IC50 value of 25 µM