DNA Vectors
Amsbio LLC SV40 large T-antigen (RFP-Puro)/ CMV lentiviral particles
SV40 large T-antigen (RFP-Puro) CMV lentiviral particles
Vector Biolabs human MDR1 shRNA Adenovirus (Ad-h-MDR1-shRNA)
This is an pre-made gene silencing adenovirus that expresses a shRNA to knockdown human MDR1 gene. The shRNA expression is driven by an U6 promoter.
The knockdown of this human gene was validated by western blot in CaCo2 cells.
Vector Biolabs Mitogen-activated protein kinase kinase kinase kinase 5 Adenovirus (Ad-MAPKKKK5)
This gene encodes a member of the serine/threonine protein kinase family, that is highly similar to yeast SPS1/STE20 kinase. Yeast SPS1/STE20 functions near the beginning of the MAP kinase signal cascades that is essential for yeast pheromone response. This kinase was shown to activate Jun kinase in mammalian cells, which suggested a role in stress response. Two alternatively spliced transcript variants encoding the same protein have been described for this gene.
Vector Biolabs Cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) Adenovirus (Ad-p18)
A family of cell cycle regulatory proteins designated mitotic inhibitors plays a major role in regulating progression through the cell cycle. These proteins bind to cyclin dependent kinases and inhibit the catalytic activity of the Cdk-cyclin complexes. Members of the mitotic inhibitor family include p21, p27, p57, p16, p15, p18 and p19. p19 ARF is an alternative splice product of the murine p16 gene and is known to induce cell cycle arrest. The human homolog p14 ARF induces cell cycle arrest in both G1 and G2/M in a p53-dependent fashion. Kip2 p57, a negative regulator of cell proliferation, inhibits several G1 cyclin/CDK complexes. The protein encoded by this gene is a member of the INK4 family of cyclin-dependent kinase inhibitors. This protein has been shown to interact with CDK4 or CDK6, and prevent the activation of the CDK kinases, thus function as a cell growth regulator that controls cell cycle G1 progression.
Vector Biolabs human LEF1 shRNA Adenovirus (Ad-h-LEF1-shRNA)
This is an pre-made gene silencing adenovirus that expresses a shRNA to knockdown human LEF1 gene. The shRNA expression is driven by an U6 promoter.
The knockdown of this human gene was validated by qPCR in MDA-MB 231 cells.
Vector Biolabs human IKKa shRNA Adenovirus (Ad-h-IKKa-shRNA)
This is an pre-made gene silencing adenovirus that expresses a shRNA to knockdown human IKKa gene. The shRNA expression is driven by an U6 promoter.
The knockdown of this human gene was validated by western blot in A549 cells.
Vector Biolabs human JAK1 shRNA Adenovirus (Ad-h-JAK1-shRNA)
This is an pre-made gene silencing adenovirus that expresses a shRNA to knockdown human JAK1 gene. The shRNA expression is driven by an U6 promoter.
The knockdown of this human gene was validated by qPCR in A549 cells.
Vector Biolabs Fibroblast growth factor 21 Adenovirus (Ad-FGF21)
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion.
Vector Biolabs Sus scrofa GNAS shRNA Adenovirus (Ad-S-GNAS-shRNA)
This is an pre-made gene silencing adenovirus that expresses a shRNA to knockdown Sus scrofa GNAS gene. The shRNA expression is driven by an U6 promoter.
The knockdown of this Sus scrofa gene was validated by western blot in IPI21 cells.
Vector Biolabs AAV Serotypes Testing Kit AAV (AAV Testing Kit)
This kits contains AAV1-CMV-GFP, AAV2-CMV-GFP, AAV5-CMV-GFP & AAV6-CMV-GFP viral stock. It can be used for testing the infection efficiency on different cell types to see which serotype works best.We also customize an AAV serotype testing kit with other serotypes of your choice (AAV 3, 8, 9, 10, DJ, DJ8, DJ9, etc), or with different promoters (CAG, SYN, etc). Please ask for customized testing kit using the link under "Add to Cart".