Bioactive Small Molecules
Medchemexpress LLC Ac-IEPD-AMC TFA | 98.01% | 671.69 (free acid) | 5 MG
Ac-IEPD-AMC TFA is a fluorescent substrate utilized to assess protease activity. It undergoes hydrolysis, releasing the fluorescent product 7-amino-4-methylcoumarin (AMC), which fluoresces under UV light and emits fluorescent signals. This product is intended for research use only.
- Fluorescent substrate for protease activity
- Undergoes hydrolysis to release AMC
- AMC fluoresces under UV light
- Inhibitors and substrates classification
- Fluorescent dye
Cayman Chemical 5-chloro TryptamInhydrochl 5mg
An analytical reference standard categorized as a tryptamine; a precursor in the synthesis of 5-chloro-N,N-DMT; intended for research and forensic applications
Cayman Chemical 8 9-DIhydrocnabIdIvarIn 5mg
An analytical reference standard that is structurally similar to known phytocannabinoids; intended for research and forensic applications
Medchemexpress LLC Tauro-ω-muricholic acid sodium | 2456348-84-6 | MFCD00082254 | 97.8% | 537.68 | C26H44NNaO7S | 5 MG
Tauro-ω-muricholic acid sodium is the sodium salt of a muricholic bile acid used as a research reagent in biochemical and physiological studies. It is supplied as a white to off-white solid with high reported purity and is investigated as a potential plasma marker for early-onset neonatal sepsis and cholestasis. Store and handle under recommended cold, moisture-controlled conditions.
- High purity (97.8%).
- Provided as a white to off-white solid.
- Soluble in DMSO; may require warming and ultrasonication.
- Storage stability: frozen storage recommended; in-solution time limits apply.
- Suitable for biochemical assays and analytical studies.
TARGETMOL CHEMICALS INC BMS-986176 1MG
Also available in 1 mL, 5 mg, 10 mg, 25 mg, 50 mg, 100 mg, 500 mg and bulk. Please contact Fisher for quotes. AAK1-IN-1 is a highly selective and potent inhibitor of adaptor associated kinase 1 (AAK1, IC50 = 2 nM). Purity 98.6%
Selleck Chemical LLC FDL169 S8795-25MG
FDL169 is a CFTR corrector that is designed to fix and restore the function of the defective CFTR protein
Selleck Chemical LLC Tuxobertinib S9786-10MM/1ML
Tuxobertinib (BDTX-189) is a potent and selective inhibitor of allosteric EGFR and HER2 oncogenic mutations with Kd of 0 2 nM 0 76 nM 13 nM and 1 2 nM for EGFR HER2 BLK and RIPK2 reapectively BDTX-189 exhibits anticancer activity
Selleck Chemical LLC IDF-11774 S8771-10MM/1ML
IDF-11774 is a hypoxia-inducible factor-1 (HIF-1) inhibitor It reduces the HRE-luciferase activity of HIF-1 (IC50 3 65 M) and blocks HIF-1 accumulation under hypoxia in HCT116 human colon cancer cells
Selleck Chemical LLC diABZI STING agonist S8796-100MG
diABZI STING agonist (diABZI STING agonist-1 Compound 3 Tautomerism) is a potent non-nucleotide STING agonist and has tremendous potential to improve treatment of cancer in humans Solutions are unstable and should be fresh-prepared
Selleck Chemical LLC AZD3229 S8780-5MG
AZD3229 is a potent pan-Kit (c-Kit) mutant inhibitor with potent single digit nM growth inhibition against a diverse panel of mutant Kit (c-Kit) driven Ba/F3 cell lines (GI50 1-50 nM) with good margin to KDR-driven effects It also inhibits PDGFR mutants (Tel-PDGFR Tel-PDGFR V561D/D842V)
Medchemexpress LLC Umbralisib R-enantiomer | 1532533-69-9 | 99.5% | 50 MG
Umbralisib R-enantiomer is the R-stereoisomer of the PI3Kδ inhibitor Umbralisib, supplied for research use. It is the less active enantiomer and shows selectivity for the δ isoform over α, β, and γ. The compound is supplied as a solid, white to light yellow powder, and is soluble in DMSO.
- Research use only.
- Less active R-enantiomer of Umbralisib.
- Selective PI3Kδ inhibitor with reduced activity versus α, β, and γ isoforms.
- Purity 99.5%.
- Molecular weight 571.55 g/mol; formula C31H24F3N5O3.
- Soluble in DMSO (33.33 mg/mL); ultrasonic assistance recommended.
- Packaged as 50 MG.
Medchemexpress LLC EXP3179 100mg | 114798-36-6 | 100 MG
EXP3179 (Losartan carboxaldehyde) is an aldehyde metabolite and synthetic intermediate of losartan supplied for research use. It is provided as a solid for biochemical and pharmacological research, with manufacturer guidance for storage and formulation.
- Intended for research use only, not for human or clinical use.
- Molecular formula C22H21ClN6O; molecular weight 420.89.
- Soluble in DMSO (≈125 mg/mL); in vivo formulation examples provided by manufacturer.
- Recommended storage: powder at -20°C; in solution -80°C for 6 months or -20°C for 1 month.
- Supplied in a 100 mg quantity for research applications.
STEMCELL Technologies IWP-2, Size: 10 mg
IWP-2 inhibits the WNT pathway (IC₅₀ = 27 nM) at the level of the pathway activator Porcupine. Porcupine is a membrane-bound acyltransferase that palmitoylates WNT proteins, which leads to WNT secretion and signaling capability. (Chen et al., Willert et al.)DIFFERENTIATION· Suppresses self-renewal of mouse embryonic stem (ES) cells and supports their conversion to epiblast-like stem cells (ten Berge et al.).· Inhibits maintenance and proliferation of mouse Lgr5+ intestinal and cochlear epithelial stem cells, demonstrating the importance of WNT signaling in these processes (Chai et al., Farin et al.).· Promotes cardiomyocyte differentiation from human pluripotent stem cells (Lian et al., Minami et al.).
