Bioactive Small Molecules
Cayman Chemical ANTIBODY SR 16832 5mg
A dual-site covalent antagonist of PPARγ; inhibits MRL20-induced allosteric activation of PPARγ in a reporter assay using HEK293T cells at 5 μM; reduces basal activity of PPARγ and inhibits binding of DHA to PPARγ in a TR-FRET assay
Medchemexpress LLC (Z)-3-phenyl-2-(propylimino)thiazolidin-4-one | 854107-48-5 | MFCD29472454 | 50mg
(Z)-3-phenyl-2-(propylimino)thiazolidin-4-one is a drug impurity
Cayman Chemical ANTIBODY LonIcerIn 10mg
A flavonoid with diverse biological activities; inhibits xanthine oxidase (IC50 = 37.4 UG/ml) and scavenges DPPH hydroxy, and superoxide radicals (IC50s = 9.2, 236.8, and 143.9 UG/ml, respectively); reduces paw edema in a mouse model of C. albicans cell wall- and complete Freund’s adjuvant-induced arthritis at 1 and 2 mg/kg three times every other day; decreases NO production and T cell proliferation in vitro at 20 and 40 UG/ml; neuroprotective against glutamate-induced neurotoxicity in rat primary cortical neurons
Cayman Chemical ANTIBODY RIvenprost 100ug
An EP4 receptor agonist (Kis = 0.7, 56, 620, and >10,000 nM, respectively, as the free acid); enhances bone morphogenic protein-induced increases in alkaline phosphatase activity in primary mouse calvarial osteoblasts at 100 nM; decreases LPS-induced increases in plasma TNF-α levels in rats; decreases trabecular separation, as well as increases bone volume, in rats at 10 UG/kg; increases proximal tibiae biomechanical strength in ovariectomized rats at 3 and 10 mg/kg
Medchemexpress LLC Benzoin methyl ether | 3524-62-7 | MFCD00008492 | 98.1% | 226.27 | C15H14O2 | 5 G
Benzoin methyl ether is a photoinitiator used in UV curing and photochemical research. It is supplied for laboratory use with a molecular formula of C15H14O2, molecular weight of 226.27 g/mol, and an assay around 98.1%. Follow recommended storage: solid at 4°C under nitrogen; solutions stored at -80°C for long-term or -20°C for short-term stability.
- Photoinitiator for UV curing and photochemical applications.
- High purity (~98.1%) suitable for research use.
- Available as small research pack for convenient handling.
- Molecular weight 226.27 g/mol; formula C15H14O2.
- Store under nitrogen at 4°C; in solvent store at -80°C (6 months) or -20°C (1 month).
STEMCELL Technologies Forskolin, Size: 10 mg
Activate adenylyl cyclase with Forskolin. This cAMP pathway activator enables NGN2-mediated transdifferentiation of human fibroblasts to cholinergic neurons (Liu et al. Nat Commun, 2013) and modulates neuronal differentiation of rat hippocampal neural progenitor cells (Hsieh et al. Proc Natl Acad Sci USA, 2004; Palmer et al. Mol Cell Neurosci, 1997). Together with other small molecules, it also enables chemical reprogramming of mouse embryonic fibroblasts to induced pluripotent stem (iPS) cells (Hou et al. Science, 2013), direct lineage reprogramming of fibroblasts to mature neurons (Hu et al. Cell Stem Cell, 2015; Li et al. Cell Stem Cell, 2015); and reprogramming of human embryonic stem (ES) cells to the “naïve” or ground state (Hanna et al. Proc Natl Acad Sci USA, 2010). Forskolin is supplied as a crystalline solid with ≥ 98% purity; Molecular weight 410.5 g/mol; CAS Number 66575-29-9. Visit STEMCELL.com for more information and related products.
Medchemexpress LLC FDI-6 | 313380-27-7 | 99.6% | 437.43 | 50 MG
FDI-6 is an inhibitor of FOXM1, designed for research use only. It directly binds to the FOXM1 protein, displacing it from genomic targets in MCF-7 breast cancer cells and leading to transcriptional down-regulation.
- Inhibits FOXM1 protein
- Displaces FOXM1 from genomic targets
- Induces transcriptional down-regulation
- Suitable for research applications
Cayman Chemical ANTIBODY SMI-16a 10mg
A Pim-1 kinase inhibitor (IC50 = 63 nM); selective for Pim-1 over a panel of 60 kinases; inhibits phosphorylation of the Pim-1 target protein Bad in DU145-Pim cells and inhibits the growth of PC3, DU145, LNCaP, K562, and MV4-11 cancer cells at 5 μM
Medchemexpress LLC HY-107367A 5mg Medchemexpress, Epertinib (hydrochloride) CAS:2071195-74-7 Purity:>98%
Medchemexpress, HY-107367A 5mg Epertinib (hydrochloride) CAS:2071195-74-7 Epertinib hydrochloride is a potent, orally active, reversible, and selective tyrosine kinase inhibitor of EGFR , HER2 and HER4 , with IC 50 s of 1.48 nM, 7.15 nM and 2.49 nM, respectively. Epertinib shows potent antitumor activity [1] . Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
![Medchemexpress LLC Carbamic acid, N-[(1S)-1-[[[1-ethyl-3-[[3-(4-morpholinyl)propyl)amino]-2,3-dioxopropyl]amino]carbon | 160399-35-9 | 99.0% | 1 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000234456.png-250.jpg)
Medchemexpress LLC Carbamic acid, N-[(1S)-1-[[[1-ethyl-3-[[3-(4-morpholinyl)propyl)amino]-2,3-dioxopropyl]amino]carbon | 160399-35-9 | 99.0% | 1 MG
AK 295 (CX 295) is a selective calpain inhibitor used in research to inhibit calpain-dependent apoptosis and provide neuroprotective effects. It is employed in studies of neurological, cardiovascular, and inflammatory diseases and is supplied with supporting documentation for laboratory use.
- Selective calpain inhibitor for apoptosis and neuroprotection studies.
- High purity suitable for biochemical and cellular assays.
- Applicable to research on neurological and cardiovascular disease models.
- Available in small milligram quantities for lab-scale experiments.
- Certificate of analysis and safety data sheet available for quality assurance.
Medchemexpress LLC Fenpropidin | 67306-00-7 | 99.5% | 273.46 g/mol | C19H31N | 5MG
Fenpropidin is a piperidine-class fungicide provided as a research reagent for in vitro and in vivo studies; it exhibits antifungal activity against various yeasts and filamentous fungi and includes recommended solubility and storage information for experimental use.
- High purity (99.5%).
- Chemical formula C19H31N; molecular weight 273.46 g/mol.
- CAS number 67306-00-7.
- Soluble in DMSO (100 mg/mL); several in vivo vehicle formulations reach ≥2.5 mg/mL.
- Storage: protect from light; store at 4°C; in solution store at -80°C (6 months) or -20°C (1 month).
- Available in small-scale quantities and solution formats (for example, 1 mg, 5 mg, 10 mg, and 10 mM in DMSO).