Bioactive Small Molecules
American Research Products Inc PrEST Antigen MAT2A
PrEST Antigen MAT2A antigen APrEST82920 for methionine adenosyltransferase II alpha Recombinant protein fragment of Human MAT2A
Medchemexpress LLC Brensocatib | 1802148-05-5 | 99.9% | 420.46 | C23H24N4O4 | 100 MG
Brensocatib is an oral dipeptidyl peptidase 1 (DPP1) inhibitor used in preclinical research to modulate neutrophil serine protease activation. The compound is supplied as a characterized research chemical with documented physicochemical properties and recommended storage conditions.
- Selective DPP1 inhibition for mechanistic and pharmacology studies.
- Potent activity reported across species, supporting translational research.
- Characterized chemical identity with CAS 1802148-05-5 and formula C23H24N4O4.
- Available in multiple quantities to support assay development and in vitro testing.
- Storage recommendations provided for powder and solution forms to preserve stability.
Medchemexpress LLC Aprepitant | 170729-80-3 | MFCD08277635 | 534.43 g/mol | C23H21F7N4O3 | 1 ML
Aprepitant is a selective, high-affinity neurokinin 1 (NK1) receptor antagonist (Kd ≈ 86 pM) provided as a research-grade reagent for in vitro pharmacology and analytical applications. For research use only.
- Selective neurokinin 1 (NK1) receptor antagonist.
- High-affinity binding with Kd ≈ 86 pM.
- Supplied as a 10 mM solution for convenient in vitro dosing.
- Suitable for pharmacology, signaling, and analytical studies.
- Well-characterized chemical identity (CAS 170729-80-3, MW 534.43 g/mol).
Medchemexpress LLC (1r)-deruxtecan | 2270986-87-1 | 99.3% | 1,034.05 g·mol⁻¹ | C52H56FN9O13 | 5 MG
(1R)-Deruxtecan is a drug-linker conjugate intended for use in antibody-drug conjugate (ADC) research. It is supplied as a small-scale research reagent with supporting analytical documentation and is not for human or clinical use.
- Drug-linker conjugate suitable for ADC development.
- High purity (~99.3%) as indicated by analytical testing.
- Available in small research pack sizes (5 mg).
- Soluble in DMSO for preparation of stock solutions.
- Provided with COA, SDS, and supporting analytical data when available.
- Intended for research use only, not for human use.
Medchemexpress LLC Biotin-PEG11-mal | 1646619-56-8 | 98.1% | 922.09 g·mol⁻¹ | C41H71N5O16S | 5 MG
Biotin-PEG11-Mal is a biotinylated, maleimide-terminated polyethylene glycol (PEG11) linker supplied as a research reagent for conjugation and PROTAC synthesis. The maleimide moiety allows selective coupling to thiol groups, while the biotin tag enables affinity capture or detection. The product is provided as a purified solid with high reported purity suitable for synthetic and biochemical workflows.
- Maleimide functional group enables thiol-selective conjugation to cysteine residues.
- Biotin tag enables affinity capture and detection in pull-down and labeling assays.
- PEG11 spacer improves solubility and provides a flexible linker between moieties.
- High reported purity (98.12%) suitable for synthetic applications.
- Offered in small laboratory pack sizes for convenient research use.
Medchemexpress LLC Pitstop 2 10mg | 1419320-73-2 | 10 MG
Pitstop 2 is a small-molecule clathrin inhibitor that binds the terminal domain of clathrin and blocks clathrin-mediated endocytosis. It is supplied for research use and has been used in studies of cell proliferation and cancer-related cellular processes.
- Inhibits clathrin-mediated endocytosis.
- Used in cell biology and anti-cancer research applications.
- High purity (98.42%) as supplied.
- Molecular weight 473.36 g/mol.
- Soluble in DMSO at 50 mg/mL (105.63 mM); ultrasonic assistance recommended.
- Store solid at 4°C protected from light; in solvent store at -80°C (2 years) or -20°C (1 year).
Medchemexpress LLC Buloxibutid | 477775-14-7 | MFCD26936332 | 475.62 | C23H29N3O4S2 | 25 MG
Buloxibutid is a selective angiotensin II type 2 (AT2) receptor agonist (C21) used in research to probe AT2-mediated signaling. It exhibits high affinity for the AT2 receptor (Ki = 0.4 nM) and markedly lower affinity for the AT1 receptor (Ki > 10 μM), supporting its use as a tool compound for AT2-specific pharmacology.
- Selective angiotensin II type 2 (AT2) receptor agonist
- High AT2 affinity (Ki = 0.4 nM)
- Minimal AT1 activity (Ki > 10 μM)
- Chemical formula C23H29N3O4S2; molecular weight 475.62
- Soluble in DMSO (50 mg/mL); in vivo formulations documented
- Storage: powder -20°C; in solvent -80°C for 6 months or -20°C for 1 month
Medchemexpress LLC Imidazole ketone era 5mg | 1801530-11-9 | 655.14 g/mol | C35H35ClN6O5 | 5 MG
Imidazole ketone erastin (IKE) is a potent, selective, and metabolically stable inhibitor of the cystine-glutamate antiporter (system xc-) that induces ferroptosis. It is supplied for research use and is used in cellular and preclinical studies of ferroptosis and tumor biology.
- Potent inhibitor of system xc- and inducer of ferroptosis.
- Metabolically stable analog of erastin for improved activity in biological systems.
- High reported purity (~99.8%) suitable for research applications.
- Molecular weight 655.14 g/mol; molecular formula C35H35ClN6O5.
- Soluble in DMSO for preparation of concentrated stock solutions.
- Supplied in small research quantities for laboratory experiments.
Selleck Chemical LLC Omaveloxolone5mg
Omaveloxolone (RTA-408) is a synthetic triterpenoid that activates the cytoprotective transcription factor Nrf2 and inhibits NF-?B signaling. Phase 2. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Gold Biotechnology Inc trans-Zeatin-riboside 250 mg
Zeatin Riboside is the most active and ubiquitous form of the naturally occurring cytokinins. Cytokinins promote cell division, stimulate shoot proliferation, inhibit root formation, slow the aging process, and activate gene expression and metabolic activity in general. In mature plants, natural cytokinin hormone levels are high during maximum growth periods. Concentrations of cytokinin used for horticulture vary between 0.1 to 10 mg/L.
Medchemexpress LLC Etimizol | 64-99-3 | 99.9% | 210.23 | 50 MG
Etimizol (Ethymisole), a nootropic agent, effectively relieves amnesia, especially when linked to hypoxic components like hypobaric hypoxia, actinomycin D, or mechanical brain injury. It works by decreasing the K-+ permeability of neuron membranes during action potential. This product is intended for research use only.
- Effectively relieves amnesia
- Decreases K-+ permeability of neuron membranes
- Suitable for research applications
- Acts as a potassium channel inhibitor