Bioactive Small Molecules
A vast array of small, non-peptide, organic compounds that are biologically active. Products include receptor antagonists, molecular probes, metabolites, GPCR ligands, neurotransmitters, ion channel modulators, and signaling activators and inhibitors.
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Tocris Bioscience™ ML 382
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MrgX1 (SNSR4) positive allosteric modulator
| Target | Sensory Neuron-Specific Receptor Agonists |
|---|---|
| CAS | 1646499-97-9 |
| Purity | >98% |
| Chemical Name or Material | Mas-Related G Protein Coupled Receptor Modulators |
| Recommended Storage | Store at Room Temperature |
| Molecular Formula | C18H20N2O4S |
| Formula Weight | 360.43 |
Tocris Bioscience™ Rucaparib camsylate
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PARP inhibitor
| Target | Poly(ADP-ribose) Polymerase Inhibitors |
|---|---|
| CAS | 1859053-21-6 |
| Purity | 98% |
| Chemical Name or Material | 8-Fluoro-1,3,4,5-tetrahydro-2-[4-[(methylamino)methyl]phenyl]-6 H-pyrrolo[4,3,2,ef][2 ]benzazepin-6-one (1 S,4 R)-7,7-dimethyl-2-oxobicyclo[2.2.1 ]heptane-1-methanesulfonic acid |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C19H18FN3O.C10H16O4S |
| Formula Weight | Observed MW: 555.66 |
| Assay Percent Range | >98% |
Tocris Bioscience™ MitoBrilliant Live 646
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Red fluorescent mitochondrial stain for live cells, Δψm dependent
| Target | Mitochondria Dyes and Probes |
|---|---|
| Recommended Storage | Store at -20°C |
Tocris Bioscience™ TC-MCH 7c
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CAS: 864756-35-4 Molecular Formula: C24H25FN2O3
| CAS | 864756-35-4 |
|---|---|
| Molecular Formula | C24H25FN2O3 |
Tocris Bioscience™ Givinostat hydrochloride
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Histone deacetylase inhibitor
| CAS | 199657-29-9 |
|---|---|
| Chemical Name or Material | [6-[(Diethylamino)methyl]-2-naphthalenyl]methyl-N-[4-[(hydroxyamino)carbonyl]phenyl]carbamate hydrochloride |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C24H27N3O4.HCl |
| Formula Weight | Observed MW: 457.95 |
| Assay Percent Range | >98% |
Tocris Bioscience™ SB 747651A dihydrochloride
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CAS: 1781882-72-1 Molecular Formula: C16H24Cl2N8O
| CAS | 1781882-72-1 |
|---|---|
| Molecular Formula | C16H24Cl2N8O |
Tocris Bioscience™ AP 20187
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Chemical inducer of protein dimerization; active in vivo
Tocris Bioscience™ RITA
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CAS: 213261-59-7 Molecular Formula: C14H12O3S2
| CAS | 213261-59-7 |
|---|---|
| Molecular Formula | C14H12O3S2 |
Tocris Bioscience™ L-655,708
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CAS: 130477-52-0 Molecular Formula: C18H19N3O4
| CAS | 130477-52-0 |
|---|---|
| Molecular Formula | C18H19N3O4 |
Tocris Bioscience™ CID 755673
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CAS: 521937-07-5 Molecular Formula: C12H11NO3
| CAS | 521937-07-5 |
|---|---|
| Molecular Formula | C12H11NO3 |
Tocris Bioscience™ STO-609 acetate
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Selective CaM kinase kinase inhibitor
| CAS | 1173022-21-3 |
|---|---|
| Solubility | Soluble to 10mM with sonication in DMSO |
| Chemical Name or Material | 7-Oxo-7H-benzimidazo[2,1-a]benz[de]isoquinoline-3-carboxylic acid acetate |
| Recommended Storage | Desiccate at Room Temperature |
| Molecular Formula | C19H10N2O3.C2H4O2 |
| Formula Weight | Observed MW: 374.35 |
| Assay Percent Range | >98% |
Tocris Bioscience™ Amlexanox
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CAS: 68302-57-8 Molecular Formula: C16H14N2O4
| CAS | 68302-57-8 |
|---|---|
| Molecular Formula | C16H14N2O4 |
Tocris Bioscience™ Thalidomide 4'-oxyacetamide-PEG2-amine
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Thalidomide-PEG2-ethylamine
Tocris Bioscience™ TRO 19622
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CAS: 22033-87-0 Molecular Formula: C27H45NO
| CAS | 22033-87-0 |
|---|---|
| Molecular Formula | C27H45NO |
Tocris Bioscience™ Calphostin C
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CAS: 121263-19-2 Molecular Formula: C44H38O14
| CAS | 121263-19-2 |
|---|---|
| Molecular Formula | C44H38O14 |