Crosslinking Reagents
American Research Products Inc Rat Soluble Cluster of differe
Rat Soluble Cluster of differentiation 40 ligand sCD40L ELISA Kit from CUSABIO Detection Range 1 87 ng/mL-120 ng/mL Sensitivity 0 47 ng/mL Sample serum plasma tissue homogenates Method Sandwich
Medchemexpress LLC Fmoc-Val-Ala-PAB-OH | 1394238-91-5 | MFCD28557282 | 99.9% | 515.60 g/mol | C30H33N3O5 | 250 MG
Fmoc-Val-Ala-PAB-OH is a protease-cleavable linker used in the synthesis of antibody-drug conjugates. It combines an Fmoc-protected Val-Ala dipeptide with a para-aminobenzyl spacer and a free carboxyl group to enable coupling and self-immolative payload release. Supplied as a high-purity solid, it includes documented solubility and storage guidelines for research use.
- Protease-cleavable Val-Ala dipeptide enables selective payload release.
- Fmoc protection facilitates solid-phase peptide and conjugation chemistry.
- Para-aminobenzyl spacer provides self-immolative release upon cleavage.
- High purity (99.88%) and characterized molecular weight for reliable synthesis.
- Soluble in DMSO with reported in vitro and in vivo formulation protocols.
- Supplied as a solid in small-scale packages suitable for research.
- Recommended storage at -20°C under inert atmosphere for stability.
Cayman Chemical ProgesTRon3bIotInyl Photo 5mg
A photoaffinity probe that consists of active progesterone, a diazirine-UV (312 nm)-sensitive moiety, and a biotin tag; can be used to detect and observe the interaction of progesterone with target proteins
Medchemexpress LLC 4-nitrophenyl 2-(pyridin-2-yldisulfanyl)ethyl carbonate | 874302-76-8 | MFCD28556879 | 99.6% | 352.39 g/mol | C14H12N2O5S2 | 5 G
PDEC-NB is a disulfide-cleavable linker used for the synthesis of antibody-drug conjugates (ADCs). It releases payloads under reducing intracellular conditions via a pyridinyl-disulfide-triggered mechanism. Supplied as a white to off-white solid for research use only.
- Used as a disulfide cleavable linker for ADC synthesis.
- Molecular weight 352.39 g/mol.
- Chemical formula C14H12N2O5S2.
- CAS number 874302-76-8.
- Appearance white to off-white solid.
- For research use only; not for human use.
Medchemexpress LLC DTME 5mg
DTME (dithio-bis-maleimidoethane) is a homobifunctional maleimide crosslinker specifically designed for conjugation between sulfhydryl groups (-SH) DTME whose molecular structure consists of two maleimide groups connected by an ethylene disulfide bridge can specifically react with thiol - containing molecules (such as cysteine residues) to form stable covalent bonds DTME allows crosslinks that can be cleaved with reducing agents such as DTT (HY-15917) DTME is commonly utilized to explore and characterize protein structure particularly oligomerization or protein interactions[1]
Medchemexpress LLC Sulfo-Cy5-Mal | 2130955-10-9 | 99.33% | 764.91 | 5 MG
Sulfo-Cy5-Mal is a fluorescent dye in the form of an active ester that reacts with thiol groups in proteins to form stable conjugates. It can be used to label proteins.
- Used to label proteins
Apexbio Technology LLC SULFO-CY5-N3-5MG
Sulfo-Cy5-N3 (CAS No 1481447-40-8) is a water-soluble fluorescent reagent commonly utilized in bioimaging and labeling applications within the field of biomedical research Originating from the family of cyanine dyes it targets biomolecular structures through azide-alkyne cycloaddition also known as click chemistry allowing for specific labeling of alkyne-modified molecules Its in vitro activity is demonstrated in the nanomolar to low micromolar range making it highly effective for precise applications Sulfo-Cy5-N3 is widely used in cell models animal studies and drug screening due to its stable fluorescence and compatibility with various biological systems Experimental concentrations typically depend on the specific research design enabling researchers to adapt usage according to the requirements of their studies
Apexbio Technology LLC SULFO-CY5-MAL-5MG
Sulfo-Cy5-Mal (CAS No 2130955-10-9) is a synthetic dye used in biomedical research originating from the family of cyanine dyes renowned for their fluorescent properties It specifically targets thiol groups enabling its application in labeling proteins and peptides This compound operates through the maleimide group reacting efficiently in conjugation processes Sulfo-Cy5-Mal demonstrates activity in the nanomolar to low micromolar range and is commonly employed in vitro for imaging tracking and biosensor applications It is extensively used in various cell models and animal studies serving as a valuable tool in drug screening and molecular diagnostics Experimental concentrations typically depend on the specific research design Its integration into assays enhances sensitivity and specificity offering valuable insights into cellular processes and molecular interactions
Apexbio Technology LLC SULFO-CY5-N3-10MG
Sulfo-Cy5-N3 (CAS No 1481447-40-8) is a water-soluble fluorescent reagent commonly utilized in bioimaging and labeling applications within the field of biomedical research Originating from the family of cyanine dyes it targets biomolecular structures through azide-alkyne cycloaddition also known as click chemistry allowing for specific labeling of alkyne-modified molecules Its in vitro activity is demonstrated in the nanomolar to low micromolar range making it highly effective for precise applications Sulfo-Cy5-N3 is widely used in cell models animal studies and drug screening due to its stable fluorescence and compatibility with various biological systems Experimental concentrations typically depend on the specific research design enabling researchers to adapt usage according to the requirements of their studies
Medchemexpress LLC Sulfo-Cy5-N3 | 1481447-40-8 | MFCD28968783 | 99.1% | 724.89 | C35H44N6O7S2 | 25 MG
Sulfo-Cy5-N3 is a sulfonated Cyanine5 fluorescent azide reagent for click chemistry labeling of biomolecules. It delivers bright red fluorescence for imaging, improved aqueous solubility compared with non-sulfonated Cy5, and is supplied as a research-grade solid. Handle protected from light and prepare stock solutions in dry DMSO according to recommended storage conditions.
- Provides bright red fluorescence with Ex/Em 642/670 nm.
- Contains an azide group for click chemistry labeling of biomolecules.
- Sulfonation improves aqueous solubility compared with non-sulfonated Cy5.
- Soluble in DMSO up to 125 mg/mL; ultrasonic bath may aid dissolution.
- High purity suitable for research use (99.1%).
- Store protected from light at -20°C; in solution store at -80°C up to 6 months.