Protein Modification Reagents
Medchemexpress LLC Dmg-peg 2000 | 160743-62-4 | 98.4% | 2000 (Average) | 50 MG
DMG-PEG 2000 is utilized in the preparation of liposomes for siRNA delivery, enhancing transfection efficiency in vitro. It is also employed for lipid nanoparticles in an oral plasmid DNA delivery approach in vivo, through surface modification, to improve mucus permeability and delivery efficiency of the nanoparticles.
- Used for liposome preparation for siRNA delivery with improved transfection efficiency in vitro.
- Used for lipid nanoparticles for oral plasmid DNA delivery with improved mucus permeability and delivery efficiency in vivo.
Medchemexpress LLC T-Boc-N-amido-PEG15-Br | 3012589-40-8 | 98.0% | C37H74BrNO17 | 50 MG
t-Boc-N-amido-PEG15-Br is a PEG-based PROTAC linker primarily used in the synthesis of PROTACs. PROTACs are designed to exploit the intracellular ubiquitin-proteasome system for the selective degradation of target proteins. This product is for research use only.
- Used in the synthesis of PROTACs
- Exploits the ubiquitin-proteasome system
- Designed to selectively degrade target proteins
- For research use only
Broadpharm t-Boc-N-amido-PEG2-acid | 1365655-91-9 | MFCD22056304 | 500 mg
t-Boc-N-amido-PEG2-acid | Purity: 98% | Mol Wt: 277.3 | 1365655-91-9 | MFCD22056304 | 500 mg
Chemscene ChemScene | Boc-NH-PEG6-amine | 250MG | CS-0115431 | 0.97 | 1091627-77-8| MFCD16619391 | 424.53
ChemScene | Boc-NH-PEG6-amine | 250MG | CS-0115431 | 0.97 | 1091627-77-8| MFCD16619391 | 424.53
TARGETMOL CHEMICALS INC Biotin-PEG4-Amide-C6-Azide 2
Also available in 1 mL, 2 mg, 5 mg, 10 mg, 50 mg, 100 mg, 200 mg and bulk. Please contact Fisher for quotes. Biotin-PEG4-Amide-C6-Azide is a PEG-based PROTAC linker utilized in PROTAC synthesis. Purity 99.19%
TARGETMOL CHEMICALS INC TAMRA-PEG3-Azide 1MG
Also available in 5 mg, 10 mg, 25 mg, 50 mg, 100 mg and bulk. Please contact Fisher for quotes. TAMRA-PEG3-Azide is a TAMRA red fluorescent dye linker with a maximum excitation/emission wavelength of 553/575 nm. Purity 95%
Avanti Polar Lipids C8 PEG2000 CERAMIDE-25MG
C8 PEG2000 Ceramide, 25MG, CAS# 212116-76-2, Purity: >99%
Medchemexpress LLC DBCO-PEG6-NHS ester | 95.99% | 737.79 | 25 MG
DBCO-PEG6-NHS ester is a click chemistry PEG reagent containing an NHS ester that reacts specifically with primary amines, such as side chains of lysine residues or aminosilane-coated surfaces, under neutral or slightly alkaline conditions, to form covalent bonds. It also contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
- Reacts specifically with primary amines via NHS ester
- Undergoes strain-promoted alkyne-azide cycloaddition (SPAAC) with azide groups
- Suitable for covalent bond formation
- Useful in click chemistry reactions
Medchemexpress LLC Nhpi-peg4-c2-nhs ester | 1415328-95-8 | MFCD28155511 | 98.9% | 508.48 | C23H28N2O11 | 50 MG
NHPI-PEG4-C2-NHS ester is an NHS-activated PEGylated linker reagent used in the synthesis of antibody-drug conjugates (ADCs). The molecule provides an activated ester for efficient coupling to primary amines and a PEG4 spacer that improves solubility and linker flexibility, supplied as a viscous liquid with high purity for research applications.
- Activated NHS ester for rapid conjugation to primary amines.
- Peg4 spacer improves aqueous solubility and linker flexibility.
- Suitable for construction of antibody-drug conjugates.
- High purity, viscous liquid form appropriate for research use.
- Store at -20°C in pure form; stability is reduced in solvent.
eMolecules Methyltetrazine-PEG9-acid | Broadpharm |656.730 | C30H48N4O12 | 97.000 | Cc1nnc(nn1)-c1ccc(OCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(O)=O)cc1 | 25mg | 627958440
Methyltetrazine-PEG9-acid | Broadpharm |656.730 | C30H48N4O12 | 97.000 | Cc1nnc(nn1)-c1ccc(OCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(O)=O)cc1 | 25mg | 627958440
Medchemexpress LLC Endo-BCN-PEG2-C2-NHS ester | 2243565-12-8 | 95.0% | 450.48 | 100 MG
endo-BCN-PEG2-C2-NHS ester is a PEG-based PROTAC linker used in the synthesis of PROTACs. PROTACs consist of two different ligands connected by a linker, where one ligand targets an E3 ubiquitin ligase and the other targets a protein of interest. This mechanism exploits the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Exploits intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
Broadpharm t-Boc-N-amido-PEG2-NHS ester | 2183440-73-3 | MFCD31381627 | 100mg
t-Boc-N-amido-PEG2-NHS ester | Putity: 98% | MW: 374.4 | 2183440-73-3 | MFCD31381627 | 100mg
Medchemexpress LLC Azide-PEG-amine | 95.0% | 25 MG
Azide-PEG-amine (MW 2000) is a PEG-based PROTAC linker, essential for synthesizing PROTACs. It acts as a versatile click chemistry reagent, featuring an azide group. This enables its participation in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne groups, and strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN groups. PROTACs utilize this linker to connect ligands, targeting E3 ubiquitin ligase and a protein of interest for selective degradation. This product is for research use only.
- PEG-based PROTAC linker for PROTAC synthesis
- Functions as a click chemistry reagent with an azide group
- Enables copper-catalyzed azide-alkyne cycloaddition (CuAAc)
- Supports strain-promoted alkyne-azide cycloaddition (SPAAC)
- Leverages ubiquitin-proteasome system for selective protein degradation
- Intended for research use only