Protein Modification Reagents
Medchemexpress LLC Dspe-PEG-NHS (N-hydroxysuccinimide ester of DSPE-PEG) | 98.0% | 2000 (average) | 100 MG
DSPE-PEG-NHS (average molecular weight 2000) is an NHS-activated PEGylated phospholipid used to introduce polyethylene glycol chains onto lipid-based nanoparticles and to conjugate amine-containing ligands via formation of stable amide bonds. It is commonly applied in liposome and micelle formulation, surface PEGylation, and ligand attachment for targeted delivery. Typical purity is 98%.
- NHS ester for efficient amine coupling reactions
- Average PEG molecular weight 2000 for steric stabilization
- Compatible with liposome and micelle formulation workflows
- Enables surface PEGylation and conjugation of targeting ligands
- High purity suitable for research applications
- Available as a dry powder for convenient storage and handling
Medchemexpress LLC Dspe-peg-fitc | 1000788-53-3 | >=95.0% | 100 MG
DSPE-PEG-FITC (average MW 10,000) is a fluorescein-labeled PEGylated phospholipid that functions as a fluorescent lipid probe for incorporation into liposomes, micelles, and other lipid-based nanocarriers. Its amphiphilic structure allows integration into lipid bilayers to enable optical labeling, tracking, and imaging of nanoparticles in vitro and in vivo.
- Fluorescent label FITC for visualization and tracking.
- Average molecular weight 10,000 Da.
- Amphiphilic structure integrates into lipid bilayers.
- Suitable for liposome, micelle, and nanoparticle formulation.
- Available in multiple package sizes for experimental flexibility.
Medchemexpress LLC DSPE-NHS | 1383932-86-2 | MFCD34561791 | 95.0% | 945.21 g/mol | C49H89N2O13P | 5 MG
DSPE-NHS is an NHS-activated phospholipid reagent used for bioconjugation and liposome/nanocarrier preparation. It contains two hydrophobic stearoyl tails and an NHS ester that reacts with primary amines to form stable amide bonds; in aqueous solution it self-assembles into lipid bilayers and is commonly used to label antibodies and conjugate proteins.
- Reacts with primary amines to form stable amide linkages.
- Self-assembles into lipid bilayers in aqueous solution.
- Suitable for antibody labeling and protein conjugation.
- Solid form with practical storage recommendations for solvent and sealed conditions.
- Provided at high purity for research applications.
Medchemexpress LLC DSPE-PEG-FITC | 1000788-53-3 | 10,000 (average) | 50 MG
DSPE-PEG-FITC (MW 10000) is a fluorescent lipid-PEG conjugate composed of a DSPE lipid anchor linked to a polyethylene glycol (PEG) chain terminated with fluorescein isothiocyanate (FITC). Supplied as a yellow-orange solid, it is used to introduce fluorescent labeling and PEGylation into liposomes, lipid nanoparticles, and other lipid-based formulations for imaging, tracking, and formulation development.
- Provides fluorescent labeling for liposomes and lipid nanoparticles.
- Adds PEGylation to improve circulation and reduce nonspecific interactions.
- Suitable for in vitro and in vivo imaging and tracking applications.
- Available in multiple package sizes including 50 mg.
- Yellow to orange solid; soluble in DMSO with sonication and warming.
- Batch-specific certificate of analysis available for analytical data.
Sigma Aldrich Fine Chemicals Biosciences Pepsin from porcine gastri100G
Pepsin from porcine gastri100G
Medchemexpress LLC Dspe-peg-fitc | 600 g/mol (average) | 5 MG
DSPE-PEG-FITC (MW 600) is a fluorescein-labeled PEGylated phospholipid used as a fluorescent lipid probe for preparation of liposomes and nanoparticles, surface labeling, and tracking in research applications. The material is supplied as a light yellow to yellow solid and is intended for laboratory research; storage is recommended at 4°C protected from light, and in solvent at -80°C for up to 6 months or at -20°C for up to 1 month.
- Fluorescent labeling for liposomes and nanoparticles.
- Amphiphilic PEGylated phospholipid enabling micelle and liposome formation.
- Average molecular weight 600 for consistent labeling performance.
- Light yellow solid for convenient storage and handling.
- Stable when stored protected from light; solvent storage at -80°C (6 months) or -20°C (1 month).
Medchemexpress LLC Azido-PEG4-azide | 182760-73-2 | ≥97.0% | 288.30 | 250 MG
Azido-PEG4-azide is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. This click chemistry reagent features an Azide group, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-containing molecules. It also undergoes strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN groups.
- PEG-based PROTAC linker
- Used for PROTAC synthesis
- Click chemistry reagent
- Contains an Azide group
- Participates in CuAAc reactions with alkyne groups
- Undergoes SPAAC reactions with DBCO or BCN groups
Medchemexpress LLC DSPE-PEG-DBCO sodium | 95.0% | 5000 (average) | 25 MG
DSPE-PEG-DBCO sodium (MW 5000) is a PEGylated phospholipid supplied as the sodium salt with an average PEG molecular weight of 5000. It is provided as a solid (white to yellow) for use in nanoparticle and liposome functionalization where copper-free click chemistry is required to attach azide-bearing ligands for targeting or payload conjugation.
- Enables copper-free click conjugation via DBCO chemistry.
- Suitable for surface functionalization of lipid nanoparticles and liposomes.
- Provides PEG shielding to improve circulation and reduce opsonization.
- Supplied as a solid with reported purity ~95.0%.
- Average molecular weight 5000 for extended PEG chains and steric stabilization.
Medchemexpress LLC 2-[2-[2-[2-(2-Bromoethoxy)ethoxy]ethoxy]ethoxy]oxane | 1803547-60-5 | 97.0% | 341.24 | 250 MG
Br-PEG4-THP is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. PROTACs are designed with two distinct ligands connected by a linker; one targets an E3 ubiquitin ligase and the other targets a specific protein. This mechanism leverages the intracellular ubiquitin-proteasome system to facilitate the selective degradation of target proteins.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Exploits ubiquitin-proteasome system
- Selectively degrades target proteins
ABclonal Technology EP400 Rabbit pAb
Predicted to enable several functions, including ATP binding activity, ATP-dependent chromatin remodeler activity, and protein antigen binding activity. Involved in histone H2A acetylation and histone H4 acetylation. Part of NuA4 histone acetyltransferase complex and Swr1 complex.
Medchemexpress LLC m-PEG5-azide | 1202681-04-6 | 100 MG
m-PEG5-azide is a PEG-based PROTAC linker used in the synthesis of PROTACs. It functions as a click chemistry reagent, containing an Azide group. It can participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with molecules containing Alkyne groups, and also strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. PROTACs themselves contain two distinct ligands connected by a linker; one targets an E3 ubiquitin ligase and the other targets the desired protein, leveraging the intracellular ubiquitin-proteasome system for selective protein degradation.
- PEG-based PROTAC linker
- Click chemistry reagent with azide group
- Facilitates copper-catalyzed azide-alkyne cycloaddition (CuAAc)
- Enables strain-promoted alkyne-azide cycloaddition (SPAAC)
- Useful in PROTAC synthesis
- Supports selective protein degradation via ubiquitin-proteasome system