Protein Modification Reagents
Medchemexpress LLC Mal-PEG8-val-cit-pab-mmaf | 1640.95 | C81H129N11O24 | 1 MG
Mal-PEG8-Val-Cit-PAB-MMAF is a drug-linker conjugate for antibody-drug conjugate (ADC) research that links a maleimide-PEG8 spacer to a Val-Cit-PAB cleavable linker and a tubulin inhibitor payload to enable targeted intracellular release.
- Cleavable Val-Cit-PAB linker for protease-triggered release.
- Maleimide group for thiol conjugation to antibodies.
- PEG8 spacer to increase hydrophilicity and solubility.
- High molecular weight (1640.95) and defined molecular formula.
- Soluble in DMSO (reported 100 mg/mL).
- Intended for research use only.
Sigma Aldrich Fine Chemicals Biosciences Collagenase from Clostridium histolyticum release of physiologically active rat pancreatic islets tested, Type V, >=1 FALGPA units/mg solid, >125 CDU/mg solid | 9001-12-1 | MFCD00130830 | 25MG
Collagenase from Clostridium histolyticum release of physiologically active rat pancreatic islets tested, Type V, >=1 FALGPA units/mg solid, >125 CDU/mg solid | 9001-12-1 | MFCD00130830 | 25MG
Medchemexpress LLC DBCO-PEG8-NHS ester | 2553412-88-5 | 98.3% | C42H55N3O14 | 50 MG
DBCO-PEG8-NHS ester is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. It functions as a click chemistry reagent, containing a DBCO group that enables strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules possessing azide groups. This product is intended for research use only.
- PEG-based PROTAC linker
- Click chemistry reagent
- Features a DBCO group for SPAAC with azide-containing molecules
- Used in the synthesis of PROTACs
Medchemexpress LLC Cl-PEG4-acid 50mg
Cl-PEG4-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]
![Medchemexpress LLC 5,8-dioxa-2,11-diazatetradecanoic acid bicyclo[6.1.0]non-4-yn-9-ylmethyl ester | 2675364-08-4 | 98.1% | 475.53 g/mol | C24H33N3O7 | 50 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000204498.png-250.jpg)
Medchemexpress LLC 5,8-dioxa-2,11-diazatetradecanoic acid bicyclo[6.1.0]non-4-yn-9-ylmethyl ester | 2675364-08-4 | 98.1% | 475.53 g/mol | C24H33N3O7 | 50 MG
BCN-endo-PEG2-maleimide is an ADC linker containing PEG spacer units, an endo-BCN strained cyclooctyne moiety, and a maleimide reactive group used for bioconjugation and click-chemistry applications. It is employed in antibody-drug conjugate research to attach payloads to azide- or thiol-containing partners, and is reported to be an oil with high purity.
- Used as an ADC linker and for click-chemistry conjugations
- Contains endo-BCN for rapid bioorthogonal reaction with azides
- Features a maleimide group for thiol-reactive conjugation
- Reported purity approximately 98.1% and appears as an oil
- Store protected from light; in solvent: -80°C (6 months), -20°C (1 month)
Medchemexpress LLC Cy5.5-PEG-biotin | 10 MG
Cy5.5-PEG-Biotin (MW 2000) is a polyethylene glycol derivative conjugated with the Cy5.5 near-infrared fluorophore and a biotin moiety. It is used as a fluorescent labeling and capture reagent for research applications, where biotin enables strong binding to streptavidin/avidin and Cy5.5 provides NIR detection.
- Cy5.5 fluorophore for near-infrared imaging and detection.
- PEG spacer (average MW 2000) enhances solubility and reduces steric hindrance.
- Biotin functional group enables high-affinity capture by streptavidin/avidin.
- Suitable for labeling proteins, nucleic acids, and surfaces in detection workflows.
- Supplied as a research reagent, intended for laboratory use.
![eMolecules 1608140-48-2 | endo-BCN-PEG8-NHS ester | Broadpharm714.806 | C34H54N2O14 | 98.000 | O=C(CCOCCOCCOCCOCCOCCOCCOCCOCCNC(=O)OC[C@@H]1[C@@H]2CCC#CCC[C@H]12)ON1C(=O)CCC1=O | 25mg | 354974901](https://assets.fishersci.com/TFS-Assets/CCG/product-images/NC1710071.jpg-250.jpg)
eMolecules 1608140-48-2 | endo-BCN-PEG8-NHS ester | Broadpharm714.806 | C34H54N2O14 | 98.000 | O=C(CCOCCOCCOCCOCCOCCOCCOCCOCCNC(=O)OC[C@@H]1[C@@H]2CCC#CCC[C@H]12)ON1C(=O)CCC1=O | 25mg | 354974901
endo-BCN-PEG8-NHS ester | Broadpharm | 1608140-48-2714.806 | C34H54N2O14 | 98.000 | O=C(CCOCCOCCOCCOCCOCCOCCOCCOCCNC(=O)OC[C@@H]1[C@@H]2CCC#CCC[C@H]12)ON1C(=O)CCC1=O | 25mg | 354974901
Medchemexpress LLC Sulfo-cyanine7-n3 | 97.6% | 763.95 g/mol | C38H47N6O7S2 | 10 MG
CY7-N3 (Sulfo-Cyanine7-N3) is a water-soluble near-infrared (NIR) azide dye designed for bioconjugation via click chemistry. The azide functional group enables copper-catalyzed azide-alkyne cycloaddition (CuAAC) and strain-promoted azide-alkyne cycloaddition (SPAAC), allowing efficient fluorescent labeling of biomolecules.
- Water-soluble NIR azide dye for click chemistry.
- Enables CuAAC and SPAAC conjugation reactions.
- Supplied as a green to dark green solid; also available as a DMSO solution.
- High purity (~97.6%) suitable for labeling applications.
- Stable when stored as a solid at 4°C and protected from light.
Medchemexpress LLC Mal-PEG2-gly-gly-phe-gly-exatecan | 1599439-54-9 | 98.6% | 1149.18 | C57H65FN10O15 | 5 MG
A drug-linker conjugate used in antibody-drug conjugate (ADC) synthesis and cancer research. It consists of an exatecan payload linked via a maleimide-PEG2-gly-gly-phe-gly linker. For research use only.
- Suitable for antibody-drug conjugate synthesis
- High purity: 98.6%
- Molecular weight: 1149.18 g/mol
- Chemical formula: C57H65FN10O15
- Soluble in DMSO
- Store at -20°C and protect from light
Medchemexpress LLC Mal-amido-PEG1-C2-NHS ester | 1260092-50-9 | 99.7% | 381.34 g/mol | C16H19N3O8 | 10 MG
Mal-amido-PEG1-C2-NHS ester is a noncleavable ADC linker that contains a maleimide group and an N-hydroxysuccinimide (NHS) ester, enabling conjugation to thiols and primary amines for antibody-drug conjugate construction and bioconjugation.
- Contains maleimide and NHS ester functional groups for thiol and amine coupling.
- Molecular weight approximately 381.34 g/mol.
- Chemical formula C16H19N3O8; white to off-white solid.
- High purity (listed as 99.69%) suitable for research applications.
- Soluble in DMSO (100 mg/mL) with recommended in vivo formulation examples.
- Store protected from light, under inert gas; stability varies by storage temperature.
Medchemexpress LLC Mc-PEG4-Val-Ala-PAB-Exatecan | 99.7% | 1153.21 | C58H69FN8O16 | 5 MG
Mc-PEG4-Val-Ala-PAB-Exatecan is an ADC drug-linker conjugate composed of a cleavable Val-Ala-PAB linker and the DNA topoisomerase I inhibitor Exatecan; supplied for research use in milligram quantities for ADC development and linker-payload studies.
- Purity: 99.7%
- Molecular weight: 1153.21
- Chemical formula: C58H69FN8O16
- Physical state: Solid
- Available in 1 MG, 5 MG, 10 MG, 25 MG, 50 MG, 100 MG
- Storage: -20°C sealed; in solvent -80°C (6 months), -20°C (1 month)
- Solubility in DMSO: ≥ 100 mg/mL