Protein Modification Reagents
eMolecules Aminooxy-PEG2-alcohol | 185022-12-2 | MFCD30182047 | 500mg
Broadpharm | Aminooxy-PEG2-alcohol | 500mg | 309208988 | BP-23251 | 98.000 | 185022-12-2 | MFCD30182047 | 121.136 | C4H11NO3
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Medchemexpress LLC Dbco-peg4-mmaf | 2360411-65-8 | 99.8% | 1266.56 g·mol⁻¹ | C69H99N7O15 | 5 MG
DBCO-PEG4-MMAF is a drug-linker conjugate used in antibody-drug conjugate research. It contains a dibenzocyclooctyne (DBCO) reactive group connected via a four-unit polyethylene glycol (PEG4) linker to the tubulin inhibitor MMAF, enabling strain-promoted alkyne-azide cycloaddition (SPAAC) for bioconjugation.
- Contains DBCO reactive group for SPAAC click chemistry.
- PEG4 spacer provides flexibility and improved solubility.
- Includes MMAF payload, a potent tubulin polymerization inhibitor.
- High purity and provided as a solid, white to off-white powder.
- Available in small research pack sizes suitable for conjugation workflows.
![Medchemexpress LLC Propanoic acid, 3-[2-[2-[2-[2-(2-pyridinyldithio)ethoxy]ethoxy]ethoxy]ethoxy]- | 581065-93-2 | 97.8% | 391.50 g·mol⁻¹ | C16H25NO6S2 | 100 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000202398.png-250.jpg)
Medchemexpress LLC Propanoic acid, 3-[2-[2-[2-[2-(2-pyridinyldithio)ethoxy]ethoxy]ethoxy]ethoxy]- | 581065-93-2 | 97.8% | 391.50 g·mol⁻¹ | C16H25NO6S2 | 100 MG
(2-pyridyldithio)-PEG4 acid is a cleavable PEG linker containing four ethylene glycol units and a 2-pyridyldithio terminal group, used to attach payloads to antibodies via disulfide chemistry for antibody-drug conjugate (ADC) synthesis and other bioconjugation applications.
- Cleavable disulfide-based linker for controlled payload release.
- Four-unit PEG spacer provides flexibility and solubility.
- 2-pyridyldithio group enables facile thiol-based conjugation.
- Suitable for ADC synthesis and general bioconjugation workflows.
- Supplied as a solid and commonly available in a 100 mg pack size.
Chemscene ChemScene | Amino-PEG1-C2-acid | 5G | CS-0114519 | 0.98 | 144942-89-2| MFCD22017475 | 133.15
ChemScene | Amino-PEG1-C2-acid | 5G | CS-0114519 | 0.98 | 144942-89-2| MFCD22017475 | 133.15
Medchemexpress LLC Protac MDM2 degrader-2 | 2249944-99-6 | MFCD32197289 | 96.0% | 1391.22 g/mol | C70H76Cl4N10O12 | 5 MG
PROTAC MDM2 Degrader-2 is a bifunctional small molecule degrader designed to recruit an E3 ligase to MDM2, promoting ubiquitination and proteasomal degradation of MDM2. The compound leads to p53 stabilization and shows antiproliferative effects in cellular assays. It is supplied for research use with characterized purity, formula, and storage recommendations.
Medchemexpress LLC Tco-PEG5-maleimide | 00-00-0 | 99.5% | C28H45N3O10 | 10MG
TCO-PEG5-maleimide is a PEG-based PROTAC linker and click-chemistry reagent that combines a maleimide reactive group with a PEG5 spacer bearing a trans-cyclooctene (TCO) moiety. It is designed for efficient bioorthogonal conjugation and thiol-selective coupling in PROTAC synthesis and bioconjugation workflows, provided as a high-purity solid with recommended low-temperature storage for stability.
- Enables rapid bioorthogonal conjugation via TCO-tetrazine click chemistry.
- Maleimide group allows thiol-selective conjugation to cysteine residues or thiol-containing linkers.
- PEG5 spacer improves aqueous solubility and reduces steric hindrance.
- High chemical purity suitable for synthesis and analytical applications.
- Available in multiple small-scale package sizes for research use.
- Stable when stored dry at low temperature; in solution requires colder storage for extended stability.
Medchemexpress LLC HY-112599 500mg Medchemexpress, Pomalidomide-PEG4-C2-NH2 CAS:2225940-52-1 Purity:>98%
Medchemexpress, HY-112599 500mg Pomalidomide-PEG4-C2-NH2 CAS:2225940-52-1 Pomalidomide-PEG4-C2-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and 4-unit PEG linker used in PROTAC technology. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Broadpharm Methyltetrazine-PEG4-amine HCl salt | 1802908-05-9 | MFCD28334553 | 100mg
Methyltetrazine-PEG4-amine HCl salt | Putity: 95% | MW: 363.4 | 1802908-05-9 | MFCD28334553 | 100mg
Medchemexpress LLC Bis-mal-lysine-peg4-tfp ester | 1426164-53-5 | 98.0% | C37H45F4N5O13 | 50 MG
Bis-Mal-Lysine-PEG4-TFP ester is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. PROTACs are compounds that leverage the intracellular ubiquitin-proteasome system to selectively degrade target proteins. They consist of two different ligands connected by a linker: one ligand binds to an E3 ubiquitin ligase, and the other binds to the target protein.
- PEG-based PROTAC linker
- Utilized in the synthesis of PROTACs
- Leverages the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
- Consists of two different ligands connected by a linker
- Ligand binds to an E3 ubiquitin ligase
- Ligand binds to the target protein