Protein Modification Reagents
Medchemexpress LLC Biotin-PEG4-Amide-C6-Azide | 1006592-62-6 | 99.1% | C27H49N7O7S | 250 MG
Biotin-PEG4-Amide-C6-Azide is a PEG-based PROTAC linker used in the synthesis of PROTACs. It is also a click chemistry reagent containing an Azide group that can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with Alkyne groups, or strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN groups. PROTACs utilize the intracellular ubiquitin-proteasome system to selectively degrade target proteins. This product is for research use only.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Click chemistry reagent with Azide group
- Undergoes copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc)
- Undergoes strain-promoted alkyne-azide cycloaddition (SPAAC) reactions
- Utilizes the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
![Alkali Scientific PEG 8000 [Polyethylene Glycol 8000], 10 Kg](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000661232.jpg-250.jpg)
Alkali Scientific PEG 8000 [Polyethylene Glycol 8000], 10 Kg
Polyethylene Glycol 8000 (PEG 8000) is a high molecular weight polymer used extensively in biochemical and molecular biology applications. With a molecular weight of 8000, PEG 8000 is often employed to induce molecular crowding, a technique that simulates intracellular environments and promotes the formation of macromolecular complexes. It is ideal for protein precipitation, enzyme stabilization, and the enhancement of chemical reactions in vitro. This reagent is also used in DNA extraction protocols and protein solubilization studies. This product is offered in a 10 kg package, providing researchers with a large supply for repeated experiments and large-scale applications.
Medchemexpress LLC m-PEG4-NH-DBCO | 2228857-36-9 | MFCD31654033 | ≥95.0% | C₂₈H₃₄N₂O₆ | 50 MG
m-PEG4-NH-DBCO is a PEG-based PROTAC linker designed for the synthesis of PROTACs. It functions as a click chemistry reagent, enabling strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. PROTACs utilize the intracellular ubiquitin-proteasome system for selective degradation of target proteins.
- PEG-based PROTAC linker
- Click chemistry reagent
- Features a DBCO group
- Enables strain-promoted alkyne-azide cycloaddition (SPAAC)
- Utilizes the ubiquitin-proteasome system
- Achieves selective degradation of target proteins
- For research use only
Medchemexpress LLC DMG-PEG-NHS, MW 2000 | 95.0% | 2000 | 50 MG
DMG-PEG-NHS, MW 2000 is a compound composed of Myristic acid and PEG linked by an amide bond, with NHS as an active ester group attached to the end of the PEG chain. It is suitable for various laboratory applications.
- Used for protein/biomolecule modification
- Suitable for gene delivery applications
- Applicable in biosensor development
Grainger Closed End Peg Rack 19.88 L Blue PK6
The Carlisle Closed End Peg Rack is a 19-7/8" long metal peg rack with closed ends to prevent items from sliding off. It has 18 pegs spaced 1" apart and can hold up to 18 tools, brooms, mops, etc. The pegs are zinc-plated steel and the rack is made of 16 gauge steel. It can be mounted to a wall with screws (not included). This heavy-duty peg rack provides an organized storage solution for garages, workshops, janitorial closets, and other utility areas.
Medchemexpress LLC Mal-PEG4-Val-Cit-PAB-MMAE | 00-00-0 | 98.0% | C73H115N11O19 | 10MG
Mal-PEG4-Val-Cit-PAB-MMAE is a drug-linker conjugate intended for antibody-drug conjugate (ADC) research. It pairs a protease-cleavable Val-Cit-PAB peptide linker with the potent MMAE payload and a maleimide thiol-reactive handle, providing a reagent for thiol-based conjugation and intracellular, enzyme-triggered payload release.
Medchemexpress LLC mPEG-N3 MW 2000 25mg
mPEG-N3 (MW 2000) can be used to modify proteins peptides and other materials The azide group can react with alkynes in aqueous solution catalyzed by copper It can also be easily reduced to an amine group PEGylation can increase solubility and stability and reduce the immunogenicity of peptides and proteins mPEG-N3 (MW 2000) can also inhibit the nonspecific binding of charged molecules to the modified surface[1]
Mitegen PEG 5000 MME, 50%(w/v), 250 ml, CAS# 9004-74-4
Use our stock solutions directly or as a component in solutions you create in your own lab. We prepare our stock solutions using high quality raw materials, ASTM Type 1 water, and sterile packaging. Our stock solutions are intended for Research and Development Use Only.
eMolecules TCO-PEG2-DBCO | Broadpharm |587.717 | C34H41N3O6 | 0.000 | O=C(CCOCCOCCNC(=O)OC1CCC\C=C\CC1)NCCC(=O)N1Cc2ccccc2C#Cc2ccccc12 | 25mg | 672542384
TCO-PEG2-DBCO | Broadpharm |587.717 | C34H41N3O6 | 0.000 | O=C(CCOCCOCCNC(=O)OC1CCC\C=C\CC1)NCCC(=O)N1Cc2ccccc2C#Cc2ccccc12 | 25mg | 672542384
Medchemexpress LLC NH2-C5-PEG4-N3-L-lysine-PEG3-N3 | 99.4% | 619.71 g/mol | C25H49N9O9 | 5 MG
A cleavable 7-unit polyethylene glycol (PEG) linker with an azide functional group used for antibody-drug conjugate synthesis and bioconjugation via click chemistry.
- Cleavable 7-unit PEG linker suitable for ADC construction.
- Azide functional group enabling copper-catalyzed and strain-promoted azide-alkyne cycloaddition.
- High purity (99.4%) for research-grade applications.
- High aqueous solubility (≥100 mg/mL) for easy handling and formulation.
- Stable as a solid at -20 °C; defined storage recommendations for solutions.
Medchemexpress LLC Biotin-PEG2-azide | 1910803-72-3 | 97.0% | 1 G
Biotin-PEG2-azide is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. It functions as a click chemistry reagent, containing an Azide group that enables it to undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with Alkyne-containing molecules. Additionally, it can participate in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules possessing DBCO or BCN groups.
- PEG-based PROTAC linker
- Click chemistry reagent
- Contains an Azide group
- Undergoes copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc)
- Participates in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions
Medchemexpress LLC Mal-amido-PEG6-acid | 1334177-79-5 | 99.3% | 100 MG
Mal-amido-PEG6-acid is a PEG-based PROTAC linker primarily used in the synthesis of PROTACs. These molecules exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins, making them suitable for research applications.
- PEG-based PROTAC linker
- Facilitates the synthesis of PROTACs
- Utilizes the intracellular ubiquitin-proteasome system
- Enables selective degradation of target proteins
- High purity (99.3%)
- Appears as an off-white to gray solid
Medchemexpress LLC 3,6,9,12,15-Pentaoxahexadecanoic acid | 16024-66-1 | 99.9% | 100 MG
m-PEG4-CH2COOH is a PEG-based PROTAC linker, a colorless to light yellow liquid with a density of 1.125 g/cm³. With a molecular weight of 266.29 and chemical formula C11H22O7, it is primarily utilized in the synthesis of PROTACs. PROTACs are compounds designed to exploit the intracellular ubiquitin-proteasome system by linking an E3 ubiquitin ligase to a target protein, thereby selectively degrading the target.
- PEG-based PROTAC linker
- Utilized in the synthesis of PROTACs
- Appears as a colorless to light yellow liquid
- Has a chemical formula of C11H22O7
- Features a molecular weight of 266.29
Medchemexpress LLC 4-Arm PEG-Azide MW 5mg
4-Arm PEG-Azide (MW 40000) (4-Arm PEG-N3 (MW 40000)) is a multi-arm PEG derivative with an azide group at each end of four arms attached to a pentaerythritol core[1]
Medchemexpress LLC N3-PEG4-C2-NHS ester | 944251-24-5 | MFCD13184948 | >90% | 388.37 g/mol | C15H24N4O8 | 50 MG
N3-PEG4-C2-NHS ester is an azide-functionalized, non-cleavable polyethylene glycol (PEG) linker containing an N-hydroxysuccinimide (NHS) ester for amine coupling and an azide (N3) group for click chemistry applications such as antibody-drug conjugate (ADC) synthesis and bioconjugation.
- Azide-functionalized 4-unit PEG linker suitable for bioconjugation.
- N-hydroxysuccinimide (NHS) ester for efficient amine coupling.
- Compatible with copper-catalyzed and strain-promoted azide-alkyne cycloaddition.
- High solubility in DMSO; stock solutions commonly prepared per datasheet guidance.
- Storage recommendations: pure form -20°C up to 3 years; in solvent -80°C for 6 months or -20°C for 1 month.