Toxins
Cayman Chemical DIgItls lnta DIgItoxIn 100mg
An anthocyanin antioxidant scavenges radicals in a TEAC assay
Cayman Chemical DIgItls lnta DIgItoxIn 250mg
An anthocyanin antioxidant scavenges radicals in a TEAC assay
Cayman Chemical CytochalasIn A 1mg
The PGE2 Quant-PAK has been desgned for the convenent precse quantfcaton of PGE2 by GC- or LC-MS t ncludes a 50 Ug val of PGE2-d4 and a precsely weghed val of unlabeled PGE2 wth the precse weght (5 mg) ndcated on the val Ths unlabeled PGE2 can be used to quantfy the PGE2-d4 standard by constructng a standard curve of peak ntensty ratos (deuterated versus unlabeled)
Cayman Chemical CytochalasIn E 1mg
A potent argnase nhbtor (K 0 5 UM for the rat lver enzyme) 40-fold more potent than NOHA as an nhbtor of argnase from mouse macrophages (C50 10-12 UM) not a substrate for any of the 3 NOS soforms does not nhbt nNOS or NOS
American Radiolabeled Chemicals Inc Tetrodotoxin Citrate, 18660-81-6, MFCD00210218, 1mg
Molecular Formula: C11H17N3O8, Molecular Weight: 319.27, Synonym: TTX citrate
AdipoGen T-2 Toxin
Chemical. CAS 21259-20-1. Formula C24H34O9. MW 466.5. Isolated from fungus Fusarium tricinctum. Common trichothecene mycotoxin, which can infect grain crops causing alimentary toxic aleukia in humans and animals. Inhibits DNA and RNA synthesis in vivo and in vitro and can induce apoptosis. In vivo the compound rapidly metabolizes to HT-2 mycotoxin a major metabolite. Inhibits protein synthesis through its high binding affinity to peptidyl transferase, which is an integral part of the 60S ribosomal subunit, resulting in activation of JNK/p38 MAPKs. Interferes with the metabolism of membrane phospholipids and increases liver lipid peroxides. Increases blood-brain barrier permeability and inhibits monoamine oxidase activity in brain. Reactive oxygen species ROS inducer.
Selleck Chemical LLC Lycorine hydrochloride-25mg
Lycorine (Galanthidine, Amarylline, Narcissine, Licorine), a natural alkaloid extracted from the Amaryllidaceae plant family, has been reported to exhibit a wide range of physiological effects, including the potential effect against cancer. It is an HCV inhibitor with strong activity.
Cayman Chemical DIgItls lnta DIgItoxIn 500mg
A dual inhibitor of Mps1/TTK and Clk2 (IC50s 5 and 3 nM respectively) selective for Mps1/TTK and Clk2 over a panel of 255 kinases at 3 M inhibit DYRK3 DYRK1A PHKG DYRK1B and Clk1 (IC50s 99 104 136 157 and 300 nM respectively) selectively inhibits the growth of Cal-51 TNBC cell over BT-474 luminal breast cancer cells (IC50s 60 and 6970 nM respectively) reduces tumor volume in a Cal-51 mouse xenograft model at 20 mg/kg
Cayman Chemical WRnr Syndrome rcQ Helcase 25mg
An analytical reference standard categorized as an imidazothiazole a racemic form of (–)-levamisole has been found as an adulterant in cocaine seized by law enforcement intended for research and forensic applications
Cayman Chemical Werner Syndrome RecQ Helicase
An antagonist of yoda1-activated Piezo1 (IC50 1.3 UM in HEK293 cells expressing the human receptor) selective for yoda1-actived Piezo1 over constituitively active Piezo1 TRPV4 and TRPC4 at 10 UM reduces the percentage of cells with yoda1-induced extracellular phosphatidylserine exposure in RBCs isolated from patients with sickle cell anemia at 10 UM inhibits yoda1-induced relaxation of isolated mouse aortic rings at 10 UM
Cayman Chemical Cholera ToxInazIde free 1mg
A secondary bile acid inhibits TCA-induced spore germination in seven C difficile strains at 0 2 v/v inhibits growth and decreases the cytotoxicity of C difficile culture supernatants to Vero cells at 0 02 v/v inhibits ionizing radiation-induced p53-dependent transcription in a reporter assay using HCT116 cells at 200 UM fecal and intestinal tissue levels are increased in a rat model of high-fat diet-induced obesity compared with rats fed a normal diet increased serum levels have been found in patients with colorectal cancer
Cayman Chemical ToxIn A from ClostrIdIM dIF
Specificity MouseExcitation max 565540498 nmEmission max 578 nmUses Flow cytometry Fluorescence microscopy
Selleck Chemical LLC Retinyl (Vitamin A) Palmitate S4126-50mg
Retinyl (Vitamin A) Palmitate is a more stable synthetic version of the essential nutrient vitamin A joined to palmitic acid
Selleck Chemical LLC 9-amino-CPT (9-Aminocamptothecin) S2653-5mg
9-amino-CPT (9-Aminocamptothecin 9-AC Aminocamptothecin 9-amino-20(S)-camptothecin) is a Topoisomerase I inhibitor with potent anticancer activities 9-amino-CPT (9-Aminocamptothecin) is an active water-insoluble derivative of camptothecin