Non-Mammalian cDNA
Abcam SB 699551 dihydrochloride, 5-HT5A receptor antagonist, 10MG
MW 584.66 g/mol, Purity >98%. Selective 5-HT₅A receptor antagonist (pKi values are 8.3, for 5-HT₅A and < 6.0 for 5-HT₁B/D, 5-HT₂A, 5-HT₂C, 5-HT₁A and 5-HT₇ receptors). Increases extracellular 5-HT levels.
The product is subject to the following: Abcam Restricted Use Statement
Genscript Corporation Fc gamma RIIIA/CD16a V176Bi
The Human Fc gamma RIIIA/CD16a Protein is a receptor for the Fc region of IgG Binds complexed or aggregated IgG and also monomeric IgG Mediates antibody-dependent cellular cytotoxicity (ADCC) and other antibody-dependent responses such as phagocytosis
Medchemexpress LLC Panasenoside | 31512-06-8 | 1 MG
Panasenoside is a flavonoid isolated from *Lilium pumilum* DC. It exhibits α-glucosidase inhibitory activity, making it suitable for research applications. It is provided as a solid with high purity.
- Exhibits α-glucosidase inhibitory activity
- Isolated from *Lilium pumilum* DC
- High purity solid appearance
- For research use only
Medchemexpress LLC Interferon alpha/beta receptor 2, recombinant human, His tag | >90.0% | 10 UG
Recombinant human interferon alpha/beta receptor subunit 2 (IFNAR2) supplied as a purified, His-tagged protein for research use. Designed for in vitro binding and receptor interaction studies, this protein is suitable for assay development, antibody characterization, and biophysical analysis. Handle and store according to supplier documentation and SDS/COA.
- Recombinant human protein expressed for accurate receptor studies.
- His tag facilitates purification and detection.
- High purity suitable for biochemical and binding assays.
- Provided in a small research pack for assay optimization.
- Validated for use in receptor interaction and antibody binding studies.
OriGene ADAM12 (NM_003474) Human Untagged Clone, 10ug
ADAM12 (untagged)-Human ADAM metallopeptidase domain 12 (ADAM12), transcript variant 1
Cayman Chemical LeukotrIen B4-d5 10ug
An internal standard for the quantification of LTB4 by GC- or LC-MS
Biotium Primary Antibody CD50 101-1D2 CF740 1/EA
Recognizes an N-glycosylated glycoprotein of 120 kDa with intra-chain disulfide bonds identified as CD50 or ICAM-3 (WS IV and V) Its epitope localizes in the D2 extracellular domain and is resistant to neuraminidase and proteases CD50 is the major ligand for LFA-1 (CD11a/CD18) and may have signalling role to increase adhesion It is expressed on thymocytes and T lymphocytes and is resistant to treatment with phosphatidylinositol (PI) phospholipase C This MAb inhibits primary mixed lymphocyte culture (MLC) but not secondary MLC cytotoxicity or proliferation induced by mitogens It blocks binding of NK1-L16 stimulated T cells to L cells expressing CD50 This MAb is excellent for staining of formalin/paraffin tissues Primary antibodies are available purified or with a selection of fluorescent CF Dyes and other labels CF Dyes offer exceptional brightness and photostability Note Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets
OriGene CTHRC1 (NM_138455) Human Untagged Clone, 10ug
CTHRC1 (untagged)-Human collagen triple helix repeat containing 1 (CTHRC1)
Medchemexpress LLC MRIA9 | 2750707-05-0 | 98.9% | 496.92 | 50 MG
MRIA9 is a chemical probe and an ATP-competitive, pan Salt-Inducible kinase (SIK) and PAK2/3 inhibitor. It exhibits IC50 values of 516 nM, 180 nM, and 127 nM for SIK1, SIK2, and SIK3, respectively. This compound is intended for research use only.
- Sensitizes SKOV3 cells to paclitaxel treatment by inducing pronounced apoptosis.
- Significantly enhances cell death in HeLa cells when combined with paclitaxel.
- Impedes centrosome function and causes mitotic spindle mispositioning in ovarian cancer cell lines.
- Prevents centrosome disjunction during the late G2 phase.
- Sensitizes ovarian cancer cells and patient-derived 3D-spheroids to paclitaxel treatment.
- Shows high oral bioavailability (F = 75-80%).
Medchemexpress LLC UT-11 | 99.6% | 400.32 | 5 MG
UT-11 is a potent, blood-brain barrier-permeable inhibitor of microsomal prostaglandin E synthase-1 (mPGES-1). It effectively inhibits PGE2 production in human and murine cells. Studies show UT-11 can dampen neuroinflammation by blunting the upregulation of mPGES-1 and other inflammatory genes in an LPS-induced inflammation mouse model.
- Potent and blood-brain barrier-permeable inhibitor
- Inhibits PGE2 production with IC50s of 0.10 μM in human (SK-N-AS) cells and 2.00 μM in murine (BV2) cells
- Dampens neuroinflammation in LPS-induced inflammation mouse models
- Blunts upregulation of mPGES-1 and inflammatory genes (IL-6, TNF-α, CCL2, CCL3, CCL4)
Abcam NAN-190 hydrobromide, 5-HT1A antagonist, 250MG
MW 474.4 g/mol, Purity >99%. Potent 5-HT₁A receptor antagonist (Ki = 6.8 nM). Also displays activity at α₂ adrenoceptors. Displays anxiogenic and anxiolytic effects. Additionally, potentiates circadian rhythm response to light.
The product is subject to the following: Abcam Restricted Use Statement
ABclonal Technology INSRR Rabbit pAb
Enables transmembrane receptor protein tyrosine kinase activity. Involved in actin cytoskeleton reorganization, cellular response to alkaline pH, and protein autophosphorylation. Part of receptor complex.