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Bottles, spin columns, filter plates, and complete purification kits containing Proteins L, A, A/G, or G immobilized on crosslinked, beaded affinity resins of various material compositions. Ideal for antibody purification and immunoprecipitation applications.
HiTrap(R) MabSelect(TM) SuRe(TM) columns are prepacked with MabSelect(TM) SuRe a BioProcess medium for purification of monoclonal antibodies from large sample volumes. The novel alkali-tolerant recombinant Protein A ligand allow cleaning-in-place (CIP).HiTrap(R) MabSelect(TM) columns are prepacked with MabSelect(TM) a bioprocess medium for capuring of Mabs from large sample volumes.
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GammaBind Plus Sepharose(R) is used for lab-scale affinity purification of IgG from a large variety of species and has better binding to rat and mouse IgG subclasses compared to GammaBind Sepharose.GammaBind Plus Sepharose(R) is GammaBind G Type 3 covalently immobilized to Sepharose(R) CL-6B by malimide linkage. GammaBind G Type 3 a recombinant form of streptococcal protein G binds to the Fc region of IgG from a variety of mammalian species. GammaBind Plus Sepharose(R) may be used to analyze and purify classes subclasses and fragments of immunoglobulins from any biological fluid or cell culture medium. Since only the Fc region is involved in binding the Fab region is still available for binding antigen.
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MAbTrap(R) is an affinity chromatography kit with everything required for small-scale IgG purification from ascites fluid serum and cell culture supernatants.
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These HiTrap columns are prepacked with MabSelect PrismA protein A chromatography resin. This affinity resin in the packed column has been improved with an optimized high-flow agarose base matrix and a genetically engineered protein ligand allowing efficient cleaning between monoclonal antibody purification runs. This allows future demands in monoclonal antibody purification to be met including processing of many bispecific antibodies..nbspEnhanced dynamic binding capacity compared with other protein A resins..nbspExcellent alkaline stability enables efficient cleaning and sanitization using 0.5-1.0 M NaOH..nbspConvenient HiTrap format for easy connection to a syringe peristaltic pump or chromatography systems such as an ÄKTA system for convenient process optimization.The enhanced alkaline stability of MabSelect PrismA also provides opportunities for more robust mAb purification using periodic counter-current chromatography. The possibility for cleaning using 1 M NaOH increases bi
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Protein G Mag Sepharose(R) are magnetic beads designed to simplify enrichment of target proteins by immunoprecipitation applications. Based on Sepharose(R) with Protein G as ligand. Protein G has high affinity for the fc region of IgG antibodies.
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.nbspNovel alkali-tolerant rProtein A ligand withstands rigorous CIP and sanitization procedures with 0.1 to 0.5 M NaOH..nbspReduces the risk of product contamination and carryover.nbspImproves performance and reduces overall costs.nbspHigh dynamic binding capacity (DBC) for high titer cultures reduces process time and amount of medium used.nbspGeneric elution profile for different monoclonal antibodies enables platform approach to purification.nbspHigh-flow agarose matrix allows the processing of large feed volumes
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HiScreen(TM) MabSelect(TM) SuRe(TM) LX is prepacked with MabSelect(TM) SuRe(TM) LX and is part of the process development platform available from Cytiva. The columns are an excellent choice for method optimization and parameter screening for capture of monoclonal antibodies when a high binding capacity is needed.
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