General Cell Based Assays
Meso Scale Discovery R-PLEX Human Visfatin ASY
The Meso Scale Discovery R-PLEX Human Visfatin Assay measures visfatin in human serum plasma and cell culture supernatants using electrochemiluminescence (ECL) detection It offers high sensitivity a 5-log dynamic range and low sample volume needs Fully quantitative with an 8-point calibration curve it is lyophilized for stability The R-PLEX platform allows multiplexing with other biomarkers This assay provides robust data for research in obesity diabetes metabolic disease and immunology
Meso Scale Discovery U-PLEX Human G-CSF ASY
The Meso Scale Discovery U-PLEX Human G-CSF Assay is a multiplex immunoassay kit that allows simultaneous measurement of Granulocyte Colony Stimulating Factor (G-CSF) in human serum plasma and cell culture supernatants It utilizes electrochemiluminescence (ECL) detection technology and provides high sensitivity broad dynamic range and intra- and inter-assay precision This assay requires 50 L or less sample volume and can be read on MSD instrument platforms It includes a plate coated with capture antibodies detection antibodies and calibrators and controls needed to generate a standard curve and measure G-CSF concentrations
Eurofins Discoverx PathHunter eXpress EGFR/EGFR Dimerization Assay, 10-Plate Kit. (93-0989E3CP5L)
The PathHunter EGFR/EGFR Dimerization eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting receptor-receptor interaction. This kit assesses ligand (e.g. EGF) induced dimerization of EGFR/EGFR receptors. This product uses EFC technology. The cell line included overexpresses EGFR target protein fused to PK alongside EGFR target protein fused to EA. Upon ligand-induced dimerization of EGFR/EGFR, detectable EFC signal is produced. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Abcam Glucose Assay Kit
Glucose Assay Kit
The product is subject to the following: Abcam Restricted Use Statement
American Research Products Inc Human Lysyl oXidase homolog 1
Human Lysyl oXidase homolog 1 (LOXL1) ELISA kit from CUSABIO Detection Range 0 156 ng/mL-10 ng/mL Sensitivity 0 039 ng/mL Sample serum plasma cell culture supernates Method Sandwich
Cayman Chemical 7deaza8bromo NAD sodIM 700ug
A derivative of NAD+ and a synthetic intermediate; has been used as an intermediate in the synthesis of cyclic and membrane-permeable diphosphate modulators of TRPM2
Sigma Aldrich Fine Chemicals Biosciences HMG CoA Reductase Assay Ki
The HMG-CoA Reductase Assay Kit is an important tool for the basic research of cholesterol and other relelated metabolic pathways.
Eurofins Discoverx PathHunter eXpress OPRM1 U2OS β-Arrestin GPCR Assay, 2-Plate Kit. (93-0213E3CP0M)
The PathHunter OPRM1 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. met 5-enkephalin) based activation of OPRM1 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged OPRM1 and EA-tagged β-Arrestin-2. Activation of OPRM1 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter Human Activin B (ACVR1C/ACVR2B) Dimerization Cell-Based Assay Kit (U2OS)
The PathHunter Human Activin B (ACVR1C/ACVR2B) Stable Cell Line Dimerization Assay (U2OS) measures ligand-induced dimerization of ACVR1C/ACVR2B. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Montana Molecular Borealis Arrestin GLP-1R Assay - 10mL
Measure arrestin signaling kinetics in real time with the live cell, fluorescent Borealis arrestin - GLP-1 Receptor (GLP1R) assay. Add the unmodified GLP-1 receptor and Borealis sensor to cells and measure robust signals the next day on an automated plate reader or fluorescence imaging system. This assay is genetically encoded and packaged in BacMam for efficient transduction in most cell types - including uniform and near 100% efficiency in HEK293 cells as well as expression in many primary or iPSC-derived cells. The kit includes the arrestin sensor BacMam, GLP1R BacMam, GRK5 BacMam, 500mM sodium butyrate in H2O, and a positive control receptor and agonist (AT1R BacMam and 5mM Angiotensin II in H2O). Borealis kits for several other receptors are also available, and larger-sized kits are available on request. Other Montana Molecular tools including the cADDis cAMP sensor can be used alongside this assay.
MOLECULAR DEPOT LLC Pyruvate Kinase Rabbit - 10 kU
Pyruvate Kinase from Rabbit Muscle is native Pyruvate Kinase purified from the rabbit muscle This product has been used as molecular tool for various biochemical applications It has also been used in a wide array of other chemical and immunological applications For in vitro research use only
Meso Scale Discovery RPLEX HUM Kallikrein3/PSA ASY
The R-PLEX Human Kallikrein 3 (PSA) Assay from Meso Scale Diagnostics is an electrochemiluminescent immunoassay for the quantitative measurement of total prostate-specific antigen (PSA) in human serum plasma and urine This assay utilizes MSD s proprietary SECTOR Imager 6000 for high sensitivity and a broad dynamic range The assay has a lower limit of detection of 0 01 ng/mL PSA and an upper limit of 100 ng/mL PSA The assay requires 25 L of sample and can be completed in under 3 hours This assay provides a sensitive accurate method for measuring PSA levels
Eurofins Discoverx PathHunter eXpress C5AR1 CHO-K1 β-Arrestin GPCR Assay, 2-Plate Kit. (93-0557E2CP0M)
The PathHunter C5AR1 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. C5a) based activation of C5AR1 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged C5AR1 and EA-tagged β-Arrestin-2. Activation of C5AR1 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Meso Scale Discovery VPLEX Plus GLP1 Active
The Meso Scale Discovery V-PLEX Plus GLP-1 Active Kit quantitatively measures active GLP-1 in serum plasma and cell culture supernatants This electrochemiluminescent immunoassay uses MSD s SULFO-TAG labels and multi-array technology for sensitive detection The kit includes a 96-well plate with a GLP-1 capture antibody a detection antibody with an MSD SULFO-TAG and calibrators for a standard curve It detects 1 5-1000 pg/mL and shows no cross-reactivity with related analytes The assay runs on MSD s SECTOR Imager 6000
Eurofins Discoverx cAMP Hunter eXpress CCR6 CHO-K1 GPCR Assay, 10-Plate Kit. (95-0069E2CP2L)
The cAMP Hunter CCR6 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. CCL20) based activation of CCR6 GPCR activity via detection of decreasing levels of intracellular cAMP. This product uses EFC technology. The cells overexpress wild type CCR6, a naturally Gi/Go coupled GPCR. Upon activation of CCR6, the decrease in levels of intracellular cAMP leads to a decreased signal from EFC when the cAMP detection kit is applied. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.