General Cell Based Assays
Promega T Cell Activation Bioassay (IL-2) 5X, 1 each
The T Cell Activation Bioassays are bioluminescent cell-based assays that overcome the limitations of existing assays and can be used for the discovery and development of novel biologics such as bispecific antibodies and CAR-T cell therapies.
PolarScreen™ ER Alpha Competitor Assay, Red
PolarScreen™ ER Alpha Competitor Assay, Red provides a sensitive and efficient method for high-throughput, fluorescence polarization-based screening of potential ER alpha ligands.
Promega NanoBiT PPI Flexi Starter System, 1 each
The NanoBiT PPI Starter Systems provide the vectors required to create the LgBiT and SmBiT protein fusions, a PRKACA:PRKAR2A positive control pair and a negative control vector. Starter systems also include the Nano-Glo Live Cell Assay System.
Promega PD-1/PD-L1 Blockade Bioassay, Propagation Model, 1 each
The PD-1/PD-L1 Blockade Bioassay, Propagation Model, allows propagation and banking of the PD-1 Effector Cells and PD-L1 aAPC/CHO-K1 Cells.
Promega NanoBiT PPI Control Pair (FKBP, FRB), 1 each
The NanoBiT PPI Starter Systems provide the vectors required to create the LgBiT and SmBiT protein fusions, a PRKACA:PRKAR2A positive control pair and a negative control vector. Starter systems also include the Nano-Glo Live Cell Assay System.
Promega mFcgammaRIV ADCC Bioassay Effector Cells, Propagation Model, 1 each
The mFcγRIV ADCC Bioassay Effector Cells, Propagation Model, provides a biologically relevant and specific MOA-based measure of mFcγRIV ADCC without the complex workflow and variability inherent in primary cell-based assays.
Promega NanoBRET TE Intracellular BET BRD Detection Reagents, 10,000 assays
NanoBRET Target Engagement Intracellular BET BRD Assay measures compound binding at select BET bromodomain target proteins within intact cells. The assay is based on NanoBRET, an energy transfer technique for measuring molecular proximity in living cells.
Promega Glucose Uptake-Glo Assay, 10ml
The Glucose Uptake-Glo Assay is a non-radioactive, plate-based, homogeneous bioluminescent method for measuring glucose uptake in mammalian cells based on the detection of 2-deoxyglucose-6-phosphate (2DG6P).
Promega PD-L1 Negative Cells, 1 each
PD-L1 Negative Cells are control cells for use with the PD-1/PD-L1 Blockade Bioassay.
Promega NanoBRET TE Intracellular HDAC Complete Kit, 1,000 assays
NanoBRET Target Engagement Intracellular HDAC Assay measures compound binding at select HDAC target proteins within intact cells. The assay is based on NanoBRET System, an energy transfer technique designed to measure molecular proximity in living cells.
Promega NanoBRET TE Intracellular BET BRD Assay, 100 assays
NanoBRET Target Engagement Intracellular BET BRD Assay measures compound binding at select BET bromodomain target proteins within intact cells. The assay is based on NanoBRET, an energy transfer technique for measuring molecular proximity in living cells.
Promega NanoBRET TE Intracellular HDAC Detection Reagents, 10,000 assays
NanoBRET Target Engagement Intracellular HDAC Assay measures compound binding at select HDAC target proteins within intact cells. The assay is based on NanoBRET System, an energy transfer technique designed to measure molecular proximity in living cells.
Promega NanoBRET TE Intracellular BET BRD Assay, 1,000 assays
NanoBRET Target Engagement Intracellular BET BRD Assay measures compound binding at select BET bromodomain target proteins within intact cells. The assay is based on NanoBRET, an energy transfer technique for measuring molecular proximity in living cells.
LanthaScreen™ TR-FRET ER beta Coactivator Assay Kit
LanthaScreen™ TR-FRET ER beta Coactivator Assay Kit provides a sensitive and robust method for high-throughput screening of potential estrogen receptor (ER) beta ligands as agonists or antagonists of ligand-dependent coactivator recruitment.
Aat Bioquest Cal-520, AM | 10x50ug
Cal-520 AM provides a robust homogeneous fluorescence-based assay tool for detecting intracellular calcium mobilization. Cal-520 AM is a new fluorogenic calcium-sensitive dye with a significantly improved signal to noise ratio and intracellular retention compared to the existing green calcium indicators (such as Fluo-3 AM and Fluo-4 AM). Cells expressing a GPCR or calcium channel of interest that signals through calcium can be preloaded with Cal-520 AM which can cross cell membrane. Once inside the cell, the lipophilic blocking groups of Cal-520™ AM are cleaved by esterases, resulting in a negatively charged fluorescent dye that stays inside cells. Its fluorescence is greatly enhanced upon binding to calcium. When cells stimulated with agonists, the receptor signals the release of intracellular calcium, which significantly increase the fluorescence of Cal-520.
