Protein Purification
MilliporeSigma™ Calbiochem™ SB 225002
A potent, selective, and competitive antagonist of the G-protein coupled receptor CXCR2 (IL-8RB; IC50 = 22 nM for the inhibition of 125I-IL-8 binding to CXCR2).
MilliporeSigma™ Calbiochem™ D-Amino Acid Oxidase Inhibitor III, AS057278
A cell-permeable pyrazolocarboxylic acid that acts as a selective D-amino acid oxidase (DAO/DAAO/DAMOX/OXDA) inhibitor (IC50 = 910nM against human DAO; [D-ser] = 10 mM) and effectively protects DAO overexpressing cultures from oxidative stress-induced cell death upon D-Ser (50 mM) exposure (ED50
MilliporeSigma™ Calbiochem™ Phenylarsine Oxide
A membrane-permeable protein tyrosine phosphatase inhibitor (IC50 = 18 μM).
MilliporeSigma™ Calbiochem™ HNMPA-(AM)3
A cell-permeable analog of HNMPA that yields the parent compound upon cleavage by cytosolic esterases.
MilliporeSigma™ Calbiochem™ Wnt Agonist II, SKL2001
The Wnt Agonist II, SKL2001 controls the biological activity of Wnt. This small molecule/inhibitor is primarily used for Biochemicals applications.
MilliporeSigma™ Calbiochem™ PP2A Activating Ligand, ITH12246
A cell-permeable, relatively non-toxic, 1,8-naphthyridine derived compound that blocks the inhibitory effect of protein phosphatase inhibitors, such as okadaic acid, on protein phosphatase 2A (PP2A)
MilliporeSigma™ Calbiochem™ Ro106-9920
A cell-permeable tetrazolopyridazine-phenylsulfoxide compound that displays anti-inflammatory properties.
MilliporeSigma™ Calbiochem™ SKF-97541
A highly potent agonist of GABAB receptor. Shown to be about 10-times more potent than baclofen.
MilliporeSigma™ Calbiochem™ β-Secretase Substrate IV, Fluorogenic
β-Secretase Substrate IV, Fluorogenic, is a highly sensitive FRET substrate. Hydrolysis of the substrate (Leu-Asp cleavage) by β-secretase results in fluorescence enhancement.
MilliporeSigma™ Calbiochem™ Apicidin, Fusarium sp.
A potent, cell-permeable inhibitor of histone deacetylase (IC50 700 pM for parasitic histone deactetylase) that also exhibits antiprotozoal and potential anti-malarial properties.
MilliporeSigma™ Calbiochem™ TCPOBOP
The most potent known member of the phenobarbital-like class of cytochrome P450 (CYP)-inducing agents.
MilliporeSigma™ Calbiochem™ MRP1 Inhibitor II, Reversan
The MRP1 Inhibitor II, Reversan controls the biological activity of MRP1. This small molecule/inhibitor is primarily used for Cell Structure applications.
MilliporeSigma™ Calbiochem™ InSolution™ JNK Inhibitor II
The InSolution™ JNK Inhibitor II, also referenced under CAS 129-56-6, controls the biological activity of JNK. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ ERO1 Inhibitor I, Erodoxin
The ERO1 Inhibitor I, Erodoxin controls the biological activity of ERO1.
MilliporeSigma™ Calbiochem™ E-Cadherin Upregulator, ResEcad
A cell-permeable isoxazolocarboxamide compound that enhances the E-cadherin protein level in lung squamous cell carcinoma H520 and colorectal adenocarcinoma SW620 cells.