Protein Purification
MilliporeSigma™ Calbiochem™ CBFβ Activator, Kartogenin
The CBFβ Activator, Kartogenin modulates the biological activity of CBFβ. This small molecule/inhibitor is primarily used for Biochemicals applications.
MilliporeSigma™ Calbiochem™ SKP2 E3 Ligase Inhibitor I, C1
A cell-permeable rhodanine compound that upregulates cellular p21Cip1/Waf1 and p27Kip1 protein levels (10μM for 16 h in 501 Mel cultures) by preventing Skp2-Cks1-mediated substrate recruitment without affecting the F-box E3 ubiquitin ligase Skp2 interaction with Cks1 or the SCF (Skp1-cullin1-F-box) c
MilliporeSigma™ Calbiochem™ AP-1/NF-κB Dual Inhibitor, SP100030
A cell-permeable, non-toxic, conformationally restricted pyrimidinecarboxamide compound that acts as a potent, reversible T-cell specific inhibitor of both AP-1 and NF-κB transcriptional activation (IC50 = 50
MilliporeSigma™ Calbiochem™ CDC25 Phosphatase Inhibitor I, BN82002
The CDC25 Phosphatase Inhibitor I, BN82002, also referenced under CAS 396073-89-5, controls the biological activity of CDC25 Phosphatase. This small molecule/inhibitor is primarily used for Phosphorylation and Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ p21-Activated Kinase Inhibitor III, IPA-3
The p21-Activated Kinase Inhibitor III, IPA-3, also referenced under CAS 42521-82-4, controls the biological activity of p21-Activated Kinase. This small molecule/inhibitor is primarily used for Phosphorylation and Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ InSolution™ Roscovitine
A potent and selective inhibitor of cyclin-dependent kinases (Cdks)
MilliporeSigma™ Calbiochem™ Wnt Synergist, QS11
A cell-permeable purine compound that binds ARFGAPs (Kd = 364 and 620 nM for AMAP1 and ARFGAP1, respectively) and acts as a broad specificity ARFGAPs inhibitor (GTPase activating proteins of ADP-ribosylation factor).
MilliporeSigma™ Calbiochem™ Arp2/3 Complex Inhibitor II, CK-869
The Arp2/3 Complex Inhibitor II, CK-869 controls the biological activity of Arp2/3. This small molecule/inhibitor is primarily used for Cell Structure applications.
MilliporeSigma™ Calbiochem™ CD45 Inhibitor VI
A cell-permeable, potent, irreversible, non-substrate competitive inhibitor of CD45/PTPRC tyrosine phosphatase activity (IC50 = 290 nM).
MilliporeSigma™ Calbiochem™ GPR119 Agonist, AS1269574
The GPR119 Agonist, AS1269574, also referenced under CAS 330981-72-1, controls the biological activity of GPR119. This small molecule/inhibitor is primarily used for Biochemicals applications.
MilliporeSigma™ Calbiochem™ InSolution™ NF-κB Activation Inhibitor
The InSolution™ NF-κB Activation Inhibitor controls the biological activity of NF-κB. This small molecule/inhibitor is primarily used for Inflammation/Immunology applications.
MilliporeSigma™ Calbiochem™ Adenosine 3',5'-cyclic Monophosphorothioate, Rp-Isomer, Triethylammonium Salt
A cell-permeable and reversible inhibitor of protein kinase A (Ki = 11 μM).
MilliporeSigma™ Calbiochem™ β-Catenin/Tcf Inhibitor III, iCRT3
The β-Catenin/Tcf Inhibitor III, iCRT3 controls the biological activity of β-Catenin/Tcf. This small molecule/inhibitor is primarily used for Biochemicals applications.
MilliporeSigma™ Calbiochem™ Caspase-9 Substrate II, Colorimetric
The Caspase-9 Substrate II, Colorimetric serves as the substrate for Caspase-9.
MilliporeSigma™ Calbiochem™ VEGF Inducer, GS4012
A cell-permeable pyridinyl-thioether compound that acts as a potent inducer of VEGF and VEGF-mediated vessel formation.