Protein Purification
MilliporeSigma™ Calbiochem™ Gö 6976
Gö 6976, CAS 136194-77-9, is a cell-permeable, reversible, and ATP-competitive inhibitor of PKC (IC50 = 7.9 nM for rat brain). Exhibits selectively for PKCα (IC50 = 2.3 nM) and βI (IC50 = 6.2 nM).
MilliporeSigma™ Calbiochem™ VEGFR Tyrosine Kinase Inhibitor VI, AAL-993
The VEGFR Tyrosine Kinse Inhibitor VI, ALL-993, also referenced under CAS 269390-77-4, controls the biological activity of VEGFR Tyrosine Kinase. This small molecule/inhibitor is primarily used for Cancer applications.
MilliporeSigma™ Calbiochem™ miR-372/3 Inhibitor, Neomycin-S
A cell-permeable neomycin derived artificial nucleobase conjugate. Inhibits the production of oncogenic miRNAs 372 (IC50 = 2.4 μM) by binding to pre-miRNAs and interrupts processing by Dicer.
MilliporeSigma™ Calbiochem™ FK-506, Streptomyces sp.
Immunosuppressant that blocks T cell proliferation in vitro by inhibiting the generation of several lymphokines, especially IL-2.
MilliporeSigma™ Calbiochem™ KT5823
Highly specific, cell-permeable, reversible, and ATP-competitive inhibitor of protein kinase G (Ki = 234 nM).
MilliporeSigma™ Calbiochem™ STAT3 Inhibitor XI, STX-0119
The STAT3 Inhibitor XI, STX-0119 controls the biological activity of STAT3. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ Aurintricarboxylic Acid
A cell-permeable polyanionic, polyaromatic compound used as a powerful inhibitor of cellular processes that are dependent on the formation of protein-nucleic acid complexes.
MilliporeSigma™ Calbiochem™ MAGL Inhibitor III, JZL184
The MAGL Inhibitor III, JZL184, also referenced under CAS 1101854-58-3, controls the biological activity of MAGL.
MilliporeSigma™ Calbiochem™ p300/CBP Inhibitor VI, L002
A cell-permeable phenylsulfonyloxyiminocyclohexadienone compound that acts as a potent, selective, and reversible inhibitor of p300 histone acetyl transferase (IC50
MilliporeSigma™ Calbiochem™ SIRT1 Activator II
The SIRT1 Activator II, also referenced under CAS 374922-43-7, modulates the biological activity of SIRT1. This small molecule/inhibitor is primarily used for Biochemicals applications.
MilliporeSigma™ Calbiochem™ MTEP Hydrochloride
A non-competitive, potent antagonist highly selective for mGlu5 receptors (IC50 =
MilliporeSigma™ Calbiochem™ Olomoucine
A purine derivative that acts as a potent, reversible and selective inhibitor of p34cdk1/cyclin B and related kinases.
MilliporeSigma™ Calbiochem™ Reserpine
Binds the vesicular monoamine transporter (VMAT2) and acts as an irreversible transport inhibitor of biogenic amines.
MilliporeSigma™ Calbiochem™ PIM3 Kinase Inhibitor VII, M-110
A cell-permeable hydroxyphenyl-propylidene-benzohydrazide compound that acts as a potent, ATP-competitive (Ki
MilliporeSigma™ Calbiochem™ Glyburide
A sulfonylurea that selectively blocks ATP-sensitive K+ channels.