Protein Purification
MilliporeSigma™ Calbiochem™ Rho Kinase Inhibitor III, Rockout
The Rho Kinase Inhibitor III, Rockout, also referenced under CAS 7272-84-6, controls the biological activity of Rho Kinase. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ Ro-31-8220
A cell-permeable, reversible, competitive, and selective inhibitor of protein kinase C (PKC; IC50 = 10 nM) over CaM kinase II (IC50 = 17 μM) and protein kinase A (IC50 = 900 nM).
MilliporeSigma™ Calbiochem™ Riluzole
A cell-permeable benzothiazole compound that potently inhibits glutamate release and blocks Na+ channels.
MilliporeSigma™ Calbiochem™ Ro-32-0432
A selective cell-permeable protein kinase C inhibitor.
MilliporeSigma™ Calbiochem™ Rotenone
A mitochondrial toxin and a potent, reversible, and competitive inhibitor of complex I (NADH-CoQ reductase) of the respiratory chain.
MilliporeSigma™ Calbiochem™ Ro106-9920
A cell-permeable tetrazolopyridazine-phenylsulfoxide compound that displays anti-inflammatory properties.
MilliporeSigma™ Calbiochem™ SB 220025
A cell-permeable, potent, reversible, ATP-competitive, and specific inhibitor of human p38 MAP Kinase (IC50 = 60nM).
MilliporeSigma™ Calbiochem™ SBHA
A cell-permeable bishydroxamic acid histone deacetylase (HDAC) inhibitor with anti-tumor properties.
MilliporeSigma™ Calbiochem™ InSolution™ SB 202190
A potent and cell-permeable inhibitor of p38 MAP kinase
MilliporeSigma™ Calbiochem™ SB 290157
A selective, high affinity, competitive antagonist of the anaphylatoxin C3a receptor. Does not antagonize C5aR or other chemotactic GPCRs.
MilliporeSigma™ Calbiochem™ γ-Secretase Inhibitor IX
Gamma-Secretase Inhibitor IX - CAS 208255-80-5, is a cell-permeable inhibitor of γ-secretase (Aβtotal IC50 = 115 nM, Aβ42 IC50 = 200 nM).
MilliporeSigma™ Calbiochem™ β-Secretase Substrate VI, Fluorogenic
A highly selective, fluorescence resonance energy transfer (FRET) peptide substrate for β-secretase (BACE); (pH ∽4.0, k
MilliporeSigma™ Calbiochem™ β-Secretase Substrate IV, Fluorogenic
β-Secretase Substrate IV, Fluorogenic, is a highly sensitive FRET substrate. Hydrolysis of the substrate (Leu-Asp cleavage) by β-secretase results in fluorescence enhancement.
MilliporeSigma™ Calbiochem™ β-Secretase Inhibitor III
The β-Secretase Inhibitor III controls the biological activity of β-Secretase. This small molecule/inhibitor is primarily used for Neuroscience applications.
MilliporeSigma™ Calbiochem™ InSolution™ γ-Secretase Inhibitor X
InSolution™ γ-Secretase Inhibitor X is a 1 mM solution in DMSO. A highly potent inhibitor of g-secretase (IC50 = 17, 48, 67 nM for Aβtotal, Aβ40 & Aβ42 in SHSY5Y cells overexpressing spβA4CTF).