Protein Purification
MilliporeSigma™ Calbiochem™ Rho Inhibitor, Rhosin
Rho Inhibitor, Rhosin, CAS 1173671-63-0, is a cell-permeable compound that directly targets Rho GEF binding domain (Kd = 354nM for RhoA), thereby prevents Rho from interacting with its GEFs.
MilliporeSigma™ Calbiochem™ Beclin-1 Activator II, retro-inverso TAT-Beclin-1
A cell-permeable, all-D-amino acid autophagy-inducing peptide.
MilliporeSigma™ Calbiochem™ PI 3-K/mTOR Inhibitor III, PKI-179
The PI 3-K/mTOR Inhibitor III, PKI-179, also referenced under CAS 1197160-28-3, controls the biological activity of PI 3-K/mTOR. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ Apoptosis Activator VII, Apoptozole
The Apoptosis Activator VII, Apoptozole, also referenced under CAS 1054543-47-3, modulates Apoptosis. This small molecule/inhibitor is primarily used for Cancer applications.
MilliporeSigma™ Calbiochem™ AICA-Riboside, 5'-Phosphate
A 5'-phosphorylated analog of membrane permeable AICA-Riboside that mimics AMP and acts as an activator of AMPK (AMP-activated protein kinase).
Thermo Scientific Chemicals Leupeptin, 90%, synthetic
CAS: 103476-89-7 Molecular Formula: 0·5 H2O4S
MilliporeSigma™ Calbiochem™ IKK-2 Inhibitor V
The IKK-2 Inhibitor V, also referenced under CAS 978-62-1, controls the biological activity of IKK-2. This small molecule/inhibitor is primarily used for Inflammation/Immunology applications.
MilliporeSigma™ Calbiochem™ Formin FH2 Domain Inhibitor, SMIFH2
The Formin FH2 Domain Inhibitor, SMIFH2, also referenced under CAS 340316-62-3, controls the biological activity of Formin FH2 Domain. This small molecule/inhibitor is primarily used for Membrane applications.
MilliporeSigma™ Calbiochem™ ALLM
Cell permeable inhibitor of calpain I (Ki = 120 nM), calpain II (Ki = 230 nM), cathepsin B (Ki = 100 nM), and cathepsin L (Ki = 600 pM).
MilliporeSigma™ Calbiochem™ InSolution™ Leupeptin, Hemisulfate, Microbial
A 50 mM (10 mg/421 μl) sterile-filtered solution of Leupeptin, Hemisulfate, Microbial in H2O.
MilliporeSigma™ Calbiochem™ β-Glucuronidase Inhibitor
The β-Glucuronidase Inhibitor controls the biological activity of β-Glucuronidase.
MilliporeSigma™ Calbiochem™ MPS1 Inhibitor III, AZ3146
A cell permeable purinone derivative that acts as a highly potent and selective inhibitor of monopolar spindle 1 kinase (MPS1; IC50 = ∽35
MilliporeSigma™ Calbiochem™ SB-277011-A Dihydrochloride
A brain-penetrant, high-affinity, and selective dopamine D3 receptor antagonist
MilliporeSigma™ Calbiochem™ γ-Secretase Inhibitor IX
Gamma-Secretase Inhibitor IX - CAS 208255-80-5, is a cell-permeable inhibitor of γ-secretase (Aβtotal IC50 = 115 nM, Aβ42 IC50 = 200 nM).
MilliporeSigma™ Calbiochem™ Cantharidic Acid
A potent inhibitor of protein phosphatase 2A (IC50 = 50 nM).