Protease Inhibitors and Phosphatase Inhibitors
MilliporeSigma™ Calbiochem™ Bupropion Hydrochloride
Bupropion is a non-selective inhibitor of dopamine and noradrenalin transporters. Also an antagonist for neuronal nicotinic acetylcholine receptors (nAChrs).
MilliporeSigma™ Calbiochem™ Casein Kinase I Inhibitor, D4476
The Casein Kinase I Inhibitor, D4476, also referenced under CAS 301836-43-1, controls the biological activity of Casein Kinase I. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ DNA Base Excision Repair Pathway Inhibitor
The DNA Base Excision Repair Pathway Inhibitor, also referenced under CAS 6960-45-8, controls the biological activity of APE1 (human apurinic/apyrimidinic endonuclease.
MilliporeSigma™ Calbiochem™ Caspase-8 Inhibitor II
The Caspase-8 Inhibitor II controls the biological activity of Caspase-8. This small molecule/inhibitor is primarily used for Cancer applications.
MilliporeSigma™ Calbiochem™ AEBSF, HCl ≥99% by HPLC
Specific irreversible inhibitor of serine proteases
MilliporeSigma™ Calbiochem™ NBD-Binding Peptide II, Cell Permeable, CTP-NBD
A cell-permeable cytoplasmic transduction peptide (CTP; YGRRARRRARR) fused to the NEMO binding domain peptide (NBD; TALDWSWLQTE) that acts as a potent inhibitor of TNFα-stimulated NF-κB activity (IC50∽ 50μM in HCT116 cells).
MilliporeSigma™ Calbiochem™ VEGFR2 Kinase Inhibitor VII, SKLB1002
The VEGFR2 Kinase Inhibitor VII, SKLB1002 controls the biological activity of VEGFR2 Kinase. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ Rotenone
A mitochondrial toxin and a potent, reversible, and competitive inhibitor of complex I (NADH-CoQ reductase) of the respiratory chain.
MilliporeSigma™ Calbiochem™ Carbonic Anhydrase IX/XII Inhibitor
The Carbonic Anhydrase IX/XII Inhibitor controls the biological activity of Carbonic Anhydrase IX/XII. This small molecule/inhibitor is primarily used for Cancer applications.
MilliporeSigma™ Calbiochem™ HIF-2α Translation Inhibitor
The HIF-2α Translation Inhibitor, also referenced under CAS 882268-69-1, controls the biological activity of HIF-2α. This small molecule/inhibitor is primarily used for Cell Structure applications.
MilliporeSigma™ Calbiochem™ Okadaic Acid, Ammonium Salt
Water-soluble analog of Okadaic Acid. Inhibits protein phosphatases 1 and 2A.
MilliporeSigma™ Calbiochem™ Caspase-1 Inhibitor I, Cell-Permeable
The Caspase-1 Inhibitor I, Cell-Permeable controls the biological activity of Caspase-1. This small molecule/inhibitor is primarily used for Cancer applications.
MilliporeSigma™ Calbiochem™ NF-κB Activation Inhibitor III
The NF-κB Activation Inhibitor III, also referenced under CAS 380623-76-7, controls the biological activity of NF-κB. This small molecule/inhibitor is primarily used for Inflammation/Immunology applications.
MilliporeSigma™ Calbiochem™ NEMO-Binding Domain Binding Peptide, Cell-Permeable, Negative Control
A cell-permeable Antennapedia-NBD mutated fusion peptide analog of NEMO-Binding Domain Binding Peptide that serves as a negative control.
MilliporeSigma™ Calbiochem™ Quercetin, Dihydrate
A cell-permeable and reversible inhibitor of PIM1 kinase (IC50 = 43nM), PI 3-K (IC50 = 3.8μM) and phospholipase A2