Protease Inhibitors and Phosphatase Inhibitors
Enzo Life Sciences Elafin (human), (recombinant) (100µg)
Alternative name: ESI, Elastase specific inhibitor, SKALP, Skin derived antileukoproteinase, Protease inhibitor WAP3. Purity: ≥90% (HPLC, SDS-PAGE, MS). MW: ~5.9kDa. Formulation: Lyophilized. Source: Produced in yeast. Long Term Storage: -20°C.
Research Products International Corp Protease Inhibitor Cocktail VI, Plant Cell, 1 Vial
Mixture of six protease inhibitors for use with plant cell extracts. Supplied in 1ml DMSO. Will inhibit proteases extracted from 30g plant tissue.
Contains:
Bestatin
E-64
Leupeptin
Pepstatin A
Phenanthroline
Specificity:
Aminopeptidases
Cysteine
Proteases
Aspartic Proteases and Metalloproteases
Abcam Enalaprilat, Angiotensin II converting enzyme inhibitor, 50MG
MW 384.4 Da, Purity >99%. Angiotensin II converting enzyme inhibitor. Inhibits angiotensin II-induced cardiac fibroblast proliferation. Active metabolite of Enalapril (ab141929). Antihypertensive agent. Active in vivo and in vitro.
The product is subject to the following: Abcam Restricted Use Statement
Cayman Chemical Caspase9 InhIbItr IIItrIf 10mg
A caspase-9 inhibitor with cardioprotective effects; reduces infarct size, LDH and CK release, and DNA smearing induced by ischemia and reperfusion in isolated rat hearts; inhibits MMP-2-induced TnI proteolysis at 30 μM
CPC Scientific DNP-Pro-Leu-Ala-Tyr-Trp-Ala-Arg-OH (trifluoroacetate salt) 0.5MG
Fluorogenic substrate for human neutrophil collagenase (HNC; MMP-8).SEQUENCE: DNP-Pro-Leu-Ala-Tyr-Trp-Ala-Arg-OH (trifluoroacetate salt)ONE-LETTER SEQUENCE: Dnp-PLAYWARMOLECULAR FORMULA: C49H63N13O13MOLECULAR WEIGHT: 1042.12STORAGE CONDITIONS: -20 5 CCAS REGISTRY NUMBER: [135662-05-4]SYNONYMS: RESEARCH AREA: CancerREFERENCES:S. Netzel-Arnett, et al., Anal. Biochem. 195, 86 (1991)SKU(s): MMPS-014A, MMPS-014B
Medchemexpress LLC NSC668394 10mg | 382605-72-3 | 452.10 g·mol^-1 | C17H12Br2N2O3 | 10 MG
NSC668394 is a small-molecule ezrin phosphorylation inhibitor used in preclinical research to study ezrin-dependent signaling and metastatic processes. It binds ezrin and reduces Thr567 phosphorylation, affecting cytoskeleton-associated signaling pathways.
- Inhibits ezrin Thr567 phosphorylation and ezrin-mediated signaling.
- Suitable for in vitro, cell-based studies due to cell permeability.
- High reported purity (99.31%) for reliable experimental results.
- Available as a solid and as a 10 mM solution in DMSO for convenience.
- Molecular weight 452.10 g·mol⁻¹; formula C17H12Br2N2O3.
Medchemexpress LLC Btx-A51 (casein kinase inhibitor A51) | 2079068-74-7 | MFCD34469352 | 98.6% | 360.88 g·mol⁻¹ | C18H25ClN6 | 50MG
BTX-A51 is a small-molecule inhibitor of casein kinase 1α (CK1α) that also shows activity against transcriptional kinases CDK7 and CDK9. Reported as orally active, it induces apoptosis in leukemia cell models and is used in preclinical studies to investigate CK1α/CDK biology. The compound is supplied as a solid powder with high analytical purity for use in biochemical, cellular, and in vivo research.
- Potent inhibitor of casein kinase 1α and transcriptional CDKs.
- Orally active with reported anti-leukemic activity.
- Induces apoptosis in leukemia cell models.
- High purity suitable for biochemical and cellular assays.
- Supplied as a solid powder, white to light yellow.
- Available in multiple pack sizes including 50 mg.
- Molecular weight 360.88 g·mol⁻¹; formula C18H25ClN6.
- Suitable for preclinical and mechanistic studies of CK1α/CDK pathways.
Carbosynth LLC. K-252A, 5mg, CAS# 99533-80-9, MF= C27H21N3O5
Application: Kinase Inhibitor (Pan Specific); Induces Apoptosis and Is Cell Permeable, Notes: K252a is a potent pan-specific protein kinase inhibitor: PKA (Ki = 18 nM), PKC (Ki = 25 nM) PKG (Ki = 20 nM)1. K252a inhibits CaMK (Ki = 1.8 nM) and phosphorylase kinase (IC50 = 1.7 nM) as well as other kinases. Induces apoptosis and is cell permeable.Solubility: Soluble in DMSO (up to 100 mg/ml)., salt: , origin/species: Fermentation product from Nocardiopsis sp., MW: 467.49
Biolegend Purified anti-SHP-2
Purified anti-SHP-2 [A20016A]; Isotype: Mouse IgG1, κ; Reactivity: Human, Mouse; Apps: WB; Size: 100 μg
Cayman Chemical PD-1PD-L1 InhIbItr 2 1mg
Prevents the interaction of PD-L1 with PD-1 with an IC50 value of 18 nM
Bioworld Protease Inhibitor Cocktail II for Bacterial Cell Extracts, 1 Vial(s)
Lyophilized mixture of five protease inhibitors for use with bacterial cell extracts. Reconstitute with 1ml DMSO and 4ml water to obtain a 5ml solution. Will treat proteases extracted from 20g E.Coli. * Contains: AEBSF, EDTA, Bestatin, E-64, Pepstatin A.* Specificity: Serine Proteases, Aminopeptidases, Cysteine Proteases, Metalloproteases and Aspartic Proteases.This product is sold for research use only.
Cayman Chemical JNK InhIbItr VII 25mg
A non-selective JNK inhibitor (IC50s = 1.54, 1.99, and 0.75 nM for JNK1, -2, and -3, respectively); inhibits phosphorylation of c-Jun in HeLa and A375 cells (EC50s = 130 and 244 nM, respectively)
Supply Solutions Phosphatase Inhibitor Cocktail 3, DMSO solution.
Phosphatase Inhibitor Cocktail 3, DMSO solution.
Cayman Chemical BTYNB IMP1 InhIbItr 5mg
An IMP1 inhibitor (IC50 = 5 μM for IMP1 binding to c-Myc mRNA); downregulates c-Myc and β-TrCP1 mRNA and reduces IMP1 protein levels in SK-MEL-2 and IGROV-1 cells; inhibits proliferation of IMP1-positive ES-2, IGROV-1, and SK-MEL-2 cells (IC50s = 2.3, 3.6, and 4.5 μM, respectively); inhibits anchorage-independent growth of SK-MEL-2 cells at 10 μM
CPC Scientific Ac-Asp-Glu-Val-Asp-CMK 1MG
ONE-LETTER SEQUENCE: Ac-DEVD-CMKMOLECULAR FORMULA: C21H31N4O11Cl1MOLECULAR WEIGHT:550.95STORAGE CONDITIONS: -20 5C, CAS REGISTRY NUMBER: [285570-60-7], SYNONYMS: Ac-Asp-Glu-Val-Asp-chloromethylketoneRESEARCH AREA: Apoptosis