Protease Inhibitors and Phosphatase Inhibitors
MilliporeSigma™ Calbiochem™ InSolution™ Nutlin-3, Racemic
A cell-permeable, potent, and selective MDM2 antagonist (IC50 = 90nM for Nutlin-3a and 13
MilliporeSigma™ Calbiochem™ Eicosapentaenoic Acid
Cell permeable. Shown to have a beneficial effect in cardiovascular diseases and inflammation. Inhibits 5-lipoxygenase and reduces thromboxane A2 production and blood viscosity.
MilliporeSigma™ Calbiochem™ Akt Inhibitor XIII, Isozyme-Selective, Akti2-1/2
The Akt Inhibitor XIII, Isozyme-Selective, Akti2-1/2 controls the biological activity of Akt. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ Proteinase K Inhibitor
Proteinase K Inhibitor is a tetrapeptidyl chloromethyl ketone compound that acts as an active-site-targeting irreversible inhibitor against proteinase K.
MilliporeSigma™ Calbiochem™ Bax-Inhibiting Peptide, Negative Control
A cell-permeable negative control of the Bax-Inhibiting Peptide, V5. Does not suppress Bax-mediated apoptosis (≈200 μM).
MilliporeSigma™ Calbiochem™ (–)-Epigallocatechin Gallate
One of the main polyphenolic constituents of green tea that exhibits potent antitumor, anti-inflammatory, and antioxidant properties.
MilliporeSigma™ Calbiochem™ 4-Hydroxyphenylretinamide
A synthetic amide of all-trans retinoic acid (RA) that displays reduced toxicity relative to RA while maintaining significant biological activity.
MilliporeSigma™ Calbiochem™ BAY 11-7082
The BAY 11-7082, also referenced under CAS 19542-67-7, controls the biological activity of TNF-α. This small molecule/inhibitor is primarily used for Inflammation/Immunology applications.
MilliporeSigma™ Calbiochem™ (+)-Brefeldin A, Eupenicillium brefeldianum
Specifically and reversibly blocks translocation of proteins from the endoplasmic reticulum (ER) to the Golgi apparatus without affecting endocytosis or lysosome function.
MilliporeSigma™ Calbiochem™ AKR1C3 Inhibitor
The AKR1C3 Inhibitor controls the biological activity of AKR1C3.
MilliporeSigma™ Calbiochem™ PKCε Translocation Inhibitor Peptide
The PKCε Translocation Inhibitor Peptide, Negative Control controls the biological activity of PKCε. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ SecinH3
A cell-permeable triazolo compound that acts as a Sec7 domain-binding, selective antagonist against cytohesin family small GEFs.
MilliporeSigma™ Calbiochem™ Hydroxyfasudil
A cell-permeable, hydroxylated metabolite of HA 1077 that displays anti-anginal properties.
MilliporeSigma™ Calbiochem™ Apoptosis Inhibitor II, NS3694
The Apoptosis Inhibitor II, NS3694, also referenced under CAS 426834-38-0, controls the biological activity of Apoptosis. This small molecule/inhibitor is primarily used for Cancer applications.
MilliporeSigma™ Calbiochem™ Staurosporine, N-Benzoyl
A cell-permeable Staurosporine derivative that displays antitumor properties.