Protease Inhibitors and Phosphatase Inhibitors
MilliporeSigma™ Calbiochem™ Pre-mRNA Splicing Inhibitor, Isoginkgetin
The Pre-mRNA Splicing Inhibitor, Isoginkgetin, also referenced under CAS 548-19-6, blocks the spliceosome-meidated splicing process.
MilliporeSigma™ Calbiochem™ Granzyme B Substrate VIII, Colorimetric
A colorimetric substrate for granzyme B (kcat/Km = 6.6 x 104 M-1s-1).
MilliporeSigma™ Calbiochem™ Proteasome Inhibitor I
The Proteasome Inhibitor I controls the biological activity of Proteasome. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.
MilliporeSigma™ Calbiochem™ Caspase-1 Inhibitor IV
The Caspase-1 Inhibitor IV, also referenced under CAS 154674-81-4, controls the biological activity of Caspase-1. This small molecule/inhibitor is primarily used for Cancer applications.
MilliporeSigma™ Calbiochem™ InSolution™ APT1 Inhibitor, palmostatin B
A 50 mM (2 mg/106.23 μL) sterile-filtered solution of APT1 Inhibitor, palmostatin B in DMSO.
MilliporeSigma™ Calbiochem™ CL-82198
A selective inhibitor of MMP-13 (IC50 = 10 μM).
MilliporeSigma™ Calbiochem™ Juglone
A highly selective cell-permeable, irreversible inhibitor of PPlases (peptidyl-prolyl cis/trans isomerases of the parvulin family).
MilliporeSigma™ Calbiochem™ Caspase-3 Inhibitor I, Cell-Permeable
The Caspase-3 Inhibitor I, Cell-Permeable controls the biological activity of Caspase-3. This small molecule/inhibitor is primarily used for Cancer applications.
MilliporeSigma™ Calbiochem™ InSolution™ γ-Secretase Inhibitor X
InSolution™ γ-Secretase Inhibitor X is a 1 mM solution in DMSO. A highly potent inhibitor of g-secretase (IC50 = 17, 48, 67 nM for Aβtotal, Aβ40 & Aβ42 in SHSY5Y cells overexpressing spβA4CTF).
MilliporeSigma™ Calbiochem™ Adenosine A3 Receptor Agonist, 2-Cl-IB-MECA
A highly selective agonist of adenosine A3 receptor (Ki = 330 pM).
MilliporeSigma™ Calbiochem™ ACA
A cell-permeable inhibitor of phospholipase A2 that blocks epinephrine-stimulated thromboxane production in platelets.
MilliporeSigma™ Calbiochem™ Myricetin
A cell-permeable flavanoid that displays anti-inflammatory, anti-diabetic and anti-cancer properties.
MilliporeSigma™ Calbiochem™ CFTR Inhibitor II, GlyH-101
CFTR Inhibitor II, GlyH-101, CAS 328541-79-3, is a cell-permeable potent, selective and reversible open-channel blocker of CFTR (Ki = 4.3 μM in CFTR-expressing FRT cells).
MilliporeSigma™ Calbiochem™ Pifithrin-α
A cell-permeable chemical inhibitor of p53.
MilliporeSigma™ Calbiochem™ Casein Kinase II Inhibitor III, TBCA
The Casein Kinase II Inhibitor III, TBCA, also referenced under CAS 934358-00-6, controls the biological activity of Casein Kinase II. This small molecule/inhibitor is primarily used for Phosphorylation and Dephosphorylation applications.