Protease Inhibitors and Phosphatase Inhibitors
MilliporeSigma™ Calbiochem™ HNMPA-(AM)3
A cell-permeable analog of HNMPA that yields the parent compound upon cleavage by cytosolic esterases.
MilliporeSigma™ Calbiochem™ Wnt Agonist II, SKL2001
The Wnt Agonist II, SKL2001 controls the biological activity of Wnt. This small molecule/inhibitor is primarily used for Biochemicals applications.
MilliporeSigma™ Calbiochem™ Ru360
A cell-permeable oxygen-bridged dinuclear ruthenium amine complex that has been shown to bind to mitochondria with high affinity (Kd = 340 pM).
MilliporeSigma™ Calbiochem™ Peroxiredoxin Inhibitor, Conoidin A
A cell-permeable nematicidal compound that covalently binds to the peroxidatic cysteine of peroxiredoxin II in T. gondii and irreversibly blocks its hyperperoxidation activity (IC50 = 23 μM).
MilliporeSigma™ Calbiochem™ LRH-1 Antagonist
A cell-permeable pyrazolylbiphenylethanone compound that targets LRH-1/NR5A2 ligand binding domain (LBD) via direct affinity interaction (Kd = 1
MilliporeSigma™ Calbiochem™ CFTR-F508del Corrector II, Corr-4a
A cell-permeable bisaminomethylbithiazole compound that is reported to rescue/correct the folding defect of CFTR δF508 mutant via direct interaction.
MilliporeSigma™ Calbiochem™ Nur77 LBD Antagonist, TMPA
A cell-permeable phenylacetate compound that blocks Nur77 (TR3) LKB1 nuclear-sequestering function by antagonizing against Nur77-LKB1 interaction via direct binding at the LKB1 LBD/ligand binding domain ( K d
MilliporeSigma™ Calbiochem™ LFM-A13
A potent, cell-permeable, reversible, substrate competitive, and specific inhibitor of Bruton's Tyrosine Kinase (BTK; IC50 = 17.2μM for human BTK
MilliporeSigma™ Calbiochem™ Caspase Modulator II, 1541B
Caspase Modulator II, 1541B primarily used in Inhibition.
MilliporeSigma™ Calbiochem™ Stauprimide
A cell-permeable ESCs (Embryonic Stem Cells) EMT (Epithelial-Mesenchymal Transition) inducer that is reported to prime/sensitize human and murine ESC cultures for much more enhanced/efficient differentiation into progenitor cells of multiple lineages.
MilliporeSigma™ Calbiochem™ Proteasome Inhibitor II
The Proteasome Inhibitor II controls the biological activity of Proteasome. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.
MilliporeSigma™ Calbiochem™ Aurora Kinase/Cdk Inhibitor
The Aurora Kinase/Cdk Inhibitor, also referenced under CAS 443797-96-4, controls the biological activity of Aurora Kinase/Cdk. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ Ro106-9920
A cell-permeable tetrazolopyridazine-phenylsulfoxide compound that displays anti-inflammatory properties.
MilliporeSigma™ Calbiochem™ PI 3-Kδ Inhibitor X, IC87114
The PI 3-Kδ Inhibitor X, IC87114, also referenced under CAS 371242-69-2, controls the biological activity of PI 3-Kδ. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ p53 Activator III, RITA
The p53 Activator III, RITA, also referenced under CAS 213261-59-7, modulates the biological activity of p53. This small molecule/inhibitor is primarily used for Activators/Inducers applications.