Protein Purification Reagents and Kits
Biotium c-Myc Oncoprotein(MYC2895R), CF740 conjugate, 0.1mg/mL
The epitope of this antibody spans the Myc tag epitope, aa 410-419 (EQKLISEEDL), which is a specific portion of an alpha helical region of human c-myc protein. Because the epitope is located at the dimerization site of the protein, the antibody is not sensitive for detecting endogenous c-myc, making it suitable for detecting Myc tagged proteins or myc overexpression. This MAb shows no cross-reaction with v-myc. c-myc is involved in the control of cell proliferation and differentiation and is amplified and/or overexpressed in a variety of tumors. Over-expression of c-myc protein occurs frequently in luminal cells of prostate intraepithelial neoplasia as well as in most primary carcinomas and metastatic disease.Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting lo
Sigma Aldrich Fine Chemicals Biosciences Granulocyte Macrophage Col10UG
Granulocyte-Macrophage Colony-Stimulating factor is mapped to human chromosome 5q21-q32.
Abcam CHM1, Antitumor agent, 10MG
MW 283.25 Da, Purity >99%. Potent antitumor agent. Antiproliferative, anti-angiogenic and anti-apoptotic in a dose dependent manner. Reduces cell viability (IC₅₀ = 0.13 - 8.2 μM) and tumor invasion. Active in vitro and in vivo. Increases expression of DR5, TRIAL, p53. Reduces tumor polymerisation and caspase activation.
The product is subject to the following: Abcam Restricted Use Statement
Creative Biomart m7GTP Agarose 1mL
Size :1 mL, Matrix :Highly cross-linked agaroseAverage particle size :45 - 165 μmLigand :m7GTPLigand concentration :5 mol m7GTP/ml gelRecommended flow rate :11.5 cm/hChemical stability :Stable to all solutions commonly used in gel filtration including 8 M urea and 6 M guanidine hydrochloride.Not stable in organic solvents!pH working range :7.5pH CIP range :4 - 9Shelf life :12 months
AURORA BIOLABS LLC TR-FRET PARP1 Trapping Assay Kit,384 rxn
PARP1 (Poly ADP-ribose Polymerase 1) is a key DNA repair enzyme that detects DNA damage and facilitates repair through PARylation, a process in which PARP1 uses NAD⁺ to add poly (ADP-ribose) chains to itself and other proteins. PARP1 activity recruits DNA repair factors to damaged sites and supports genome stability. PARP1 is frequently overexpressed in several cancers, including breast, ovarian, prostate, and lung cancers, making it an important therapeutic target. Some PARP inhibitors not only block PARP1 catalytic activity but also trap PARP1 on damaged DNA, preventing DNA repair and leading to cancer cell death, particularly in BRCA-mutant tumors. The TR-FRET PARP1 Trapping Assay Kit is designed to quantitatively measure PARP1-DNA trapping activity and evaluate compounds that modulate PARP1 binding and trapping for cancer research and drug discovery applications.
Genscript Corporation EpCAM/TROP1Biotin His Avi
Epithelial Cellular Adhesion Molecule (EpCAM) also known as KS1/4 gp40 GA733-2 17-1A and TROP 1 is a 40 kDa transmembrane glycoprotein that consists of a 242 amino acid (aa) extracellular domain with two EGF like repeats a 23 aa transmembrane segment and a 26 aa cytoplasmic domain
Genscript Corporation CD96/TACTILEBiotin His Av
The receptors CD96 and TIGIT are expressed on the surface of T and natural killer (NK) cells and recent studies suggest both play important inhibitory roles in immune function CD96 has been shown to modulate immune cell activity in mice with Cd96-/- mice displaying hypersensitive NK-cell responses to immune challenge and significant tumor resistance The counterbalance between the putative inhibitory CD96 and TIGIT receptors and the activating receptor CD226 offers unique strategies for immuno-oncology drug development
Biolegend Purified Keratin 14 pAb
Purified Keratin 14 pAb [Poly19053]; Isotype: Rabbit Polyclonal; Reactivity: Human; Apps: IHC; Size: 100 μL
Tosoh Bioscience LLC TSKGEL ODS-80TS 2X150
Column, Reversed Phase Chromatography; Tosoh TSKgel ODS-80Ts; Media: Silica; Particle: 5 micrometer; Pore Size: 80 angstrom; 2mm I.D. x 15cm Length; Mini-Bore