Tissue Lysates
Cayman Chemical SynthetIc Lupulon 1mg
A beta-acid; active against B. subtilis and S. aureus (MICs = 1 and 1.2 UG/ml, respectively), and T. b. brucei and L. m. mexicana (IC50s = 0.9 and 4.7 UG/ml, respectively); scavenges DPPH radicals in a cell-free assay and inhibits lipid peroxidation in rat brain homogenates (IC50s = 25 and 39 µM, respectively); reduces proliferation, cell migration, and capillary tube formation in HUVECs at 2.5 to 50 UG/ml; lupulone (40 UG/ml) activates the extrinsic apoptotic death pathway in SW480 and SW620 colon cancer cells.
Cayman Chemical MItochondrIal ComP I AcTV 10mL
An MC1R antagonist (IC50 7.23 nM) selective for MC1R over MC2R (IC50 10000 nM) but does antagonize 5-HT2B and 5-HT1A receptors (IC50s 9.66 and 16.9 nM respectively) inhibits MCH-induced [35S]GTPYS binding and calcium influx in HEK293 cells expressing human MC1R at 3 nM reduces stress-induced decreases in the time spent in the open arms of the elevated plus maze in mice at 1 3 and 10 mg/kg decreases immobility time in the forced swim test in mice
Cayman Chemical MItochondrIal Complex IV 10mL
A G protein-biased agonist of GPR84 inhibits forskolin-induced cAMP production in CHO cells expressing human GPR84 (EC50 0.00598 nM) does not induce B-arrestin recruitment at concentrations up to 80 UM
Cayman Chemical NR5A1C247SC412S mutnth 100ug
Source: Recombinant human N-terminal His-tagged HR5A1 (C247S, C412S mutant) expressed in E. coli • Amino acids: 218-461 • MW: 31.01 kDa
Biolegend D2-40 Lymphatic Endothelial Ma
D2-40 Lymphatic Endothelial Marker mAb [D2-40]; Isotype: Mouse IgG1, κ; Reactivity: Human; Apps: IHC; Size: 6 mL
Biolegend D2-40 Lymphatic Endothelial Ma
D2-40 Lymphatic Endothelial Marker mAb [D2-40]; Isotype: Mouse IgG1, κ; Reactivity: Human; Apps: IHC; Size: 100 μL
Cayman Chemical BafIlomycIn B1 100ug
A bacterial metabolite; inhibits the activity of rat liver lysosomal V-ATPase in a concentration-dependent manner; induces autophagosome accumulation in MCF-7 cells from 10-1,000 nM; inhibits chloroquine-induced apoptosis in primary CGNs at 1 nM; reduces viral genome copy numbers in the culture supernatant of Vero E6 cells infected with H1N1 influenza A
Cayman Chemical -FluvalInate 100mg
A pyrethroid acaricide; induces tail currents in AmNav1 and VdNav1 channels expressed Xenopus oocytes (EC50s = 60 and 160 nM, respectively) with a faster tail current decay in VdNav1 channels; topical application at 2 µl in combination with coumaphos, atrazine, 2,4-DMPF, chlorpyriphos, and chlorothalonil does not affect honeybee queen mass, egg-laying patterns, or the mass of daughter worker bees at emergence