General Chemistry Solutions
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Filtered Search Results
Medchemexpress LLC β-secretase inhibitor IV | 797035-11-1 | MFCD09037559 | >98.0% | 578.72 g/mol | C31H38N4O5S | 5 MG
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β-Secretase Inhibitor IV is a cell-active small-molecule inhibitor of BACE-1 (β-secretase) used in research on amyloid precursor protein processing and Alzheimer's disease pathways. It shows low-nanomolar biochemical potency (IC50 = 15.6 nM at 2 nM BACE-1; 16.3 nM at 100 pM BACE-1). Chemical identifiers: C31H38N4O5S; MW 578.72 g/mol; CAS 797035-11-1.
- Potent inhibition at low nanomolar concentrations.
- Demonstrated cell activity in cell-based assays.
- Suitable for in vitro and cell-based BACE-1 studies.
- High purity material (>98%) available for research.
- Small-molecule format compatible with standard assay workflows.
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Sigma Aldrich Fine Chemicals Biosciences Iodine monoxide | 12029-98-0 | MFCD00003543 | 4 L | 0.02 M in Tetrahydrofuran/Pyridine/Water (70:20:10)
Iodine monoxide | Purity: Not specified | Mol Wt: 227.89 | CAS No: 12029-98-0 | MDL No: MFCD00003543 | 4LThis iodine monoxide solution can function as an oxidizing agent for oxidation reactions in organic synthesis. The 0.02 molar I2O is dissolved in a 70:20:10 volume ratio mixture of tetrahydrofuran, pyridine, and water solvents. The product is provided in 4 liter poly coated glass bottles.
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Medchemexpress LLC Chromium(III) potassium sulfate dodecahydrate | 7788-99-0 | ≥98.0% | 499.40 g·mol⁻¹ | KCr(SO4)2·12H2O | 100 G
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Chromium(III) potassium sulfate dodecahydrate is an inorganic salt used as a laboratory reagent and microscopic fixative. It is supplied at high purity for analytical and histological applications and is characterized by its defined dodecahydrate form and solubility in aqueous media.
- Inorganic chromium(III) salt with defined hydration (dodecahydrate).
- High purity (≥98.0%) suitable for laboratory and analytical use.
- Molecular weight 499.40 g·mol⁻¹; formula KCr(SO4)2·12H2O.
- Soluble in water and forms stable aqueous solutions.
- Commonly used as a fixative in microscopy and in analytical chemistry.
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Medchemexpress LLC ICL-CCIC-0019 10mg | 936498-64-5 | 572.46 g/mol | C26H44Br2N4 | 10 MG
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ICL-CCIC-0019 is a small-molecule inhibitor of choline kinase α (CHKα) used in preclinical cancer research. It decreases phosphocholine levels and induces G1 cell-cycle arrest, endoplasmic reticulum stress, and apoptosis in cancer cell lines.
- Inhibits choline kinase α (CHKα) activity.
- Induces G1 cell-cycle arrest and apoptosis in cancer cell lines.
- Confirmed purity by HPLC: 95.38%.
- Provided as a dibromide pyridinium salt (C26H44Br2N4).
- Store sealed at -20°C; in solvent, store at -80°C up to 6 months.
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Medchemexpress LLC Cathepsin G inhibitor I | 429676-93-7 | MFCD28137715 | >99.0% | 620.63 g/mol | C36H33N2O6P | 1 MG
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Cathepsin G Inhibitor I is a selective, reversible, competitive, non-peptide inhibitor of cathepsin G used for biochemical and cellular research to inhibit cathepsin G activity.
- Selective reversible competitive inhibitor of cathepsin G (IC50 = 53 nM; Ki = 63 nM).
- High purity solid, white to off-white, suitable for analytical and bioassay work.
- Molecular formula C36H33N2O6P; molecular weight 620.63 g/mol.
- Recommended storage: sealed, away from moisture and light; in solvent: -80°C up to 6 months, -20°C up to 1 month.
- Suitable for biochemical assays and cellular studies to probe cathepsin G function.
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Medchemexpress LLC Human PD-L1 inhibitor I | 2135542-86-6 | 98.9% | 2350.58 | 10 MG
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Human PD-L1 inhibitor I is a hPD-1 peptide ligand with a KD of 3.39 μM. It may disturb the binding of hPD-L1 to hPD-1.
- hPD-1 peptide ligand
- KD of 3.39 μM
- May disturb the binding of hPD-L1 to hPD-1
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Medchemexpress LLC 4-(3-chloro-4-fluoroanilino)-6-(pyridin-3-ylmethylamino)-1,7-naphthyridine-3-carbonitrile | 871307-18-5 | MFCD10566771 | 99.4% | 404.83 g/mol | C21H14ClFN6 | 50MG
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Tpl2 Kinase Inhibitor 1 is a small-molecule, ATP-competitive inhibitor of the Tpl2 (MAP3K8/COT) kinase with demonstrated biochemical and cellular activity. It has a biochemical IC50 of 50 nM and reduces LPS-induced TNF-α production in cellular assays. The compound is supplied as a purified solid and is also available as a 10 mM solution in DMSO for research applications.
- Selective Tpl2 (MAP3K8) inhibitor with biochemical IC50 = 50 nM.
- Reduces LPS-induced TNF-α production in cellular assays (cellular IC50s reported).
- Molecular formula C21H14ClFN6; molecular weight 404.83 g/mol.
- Purity 99.42% as listed by supplier.
- Available as solid in multiple quantities and as 10 mM in 1 mL DMSO.
- Suitable for in vitro and cellular research applications.
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Medchemexpress LLC Bromodomain inhibitor-8 | 1300031-70-2 | 98.0% | 1 ML
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Bromodomain inhibitor-8 (Intermediate 21) is a BET bromodomain inhibitor. This compound is used in research for treating autoimmune and inflammatory diseases. It has a high purity of 98.02% and a CAS number of 1300031-70-2, providing a reliable option for various experimental applications.
- Potent BET bromodomain inhibitor
- Useful in autoimmune and inflammatory disease research
- High purity for reliable experimental results
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Cayman Chemical Sodium Phosphate Stock Soluti
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A concentrated buffer solution
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LaMarKa Chemical Company Xylene Cyanol Solution pH 3.0, 4l
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Xylene Cyanol Solution pH 3.0, 4l Plastic Jug
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Selleck Chemical LLC LDN-192960 S3406-5mg
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LDN-192960 (Compd 1) is a potent inhibitor of Haspin and Dual-specificity Tyrosine-regulated Kinase 2 (DYRK2) with IC50 of 10 nM and 48 nM respectively
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Medchemexpress LLC Pemirolast potassium | 100299-08-9 | 99.99% | 1 ML
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Pemirolast potassium is an orally active antiallergic agent used for research into bronchial asthma and conjunctivitis. It has been shown to attenuate hypersensitivity reactions, inhibit the release of various mediators from eosinophils and mast cells, and prevent the activation of human eosinophils, thereby alleviating allergic diseases.
- Orally active antiallergic agent
- Attenuates hypersensitivity reactions
- Used for bronchial asthma and conjunctivitis research
- Inhibits mediator release from eosinophils
- Prevents activation of human eosinophils
- Inhibits activation of signal transduction phospholipases in mast cells
- Reduces cisplatin-induced kaolin intake
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Apexbio Technology LLC LDN 57444 668467-91-2 10mM (in 1mL DMSO)
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LDN 57444 (CAS 668467-91-2) is a reversible competitive inhibitor of ubiquitin C-terminal hydrolase-L1 (Uch-L1) displaying an IC50 of 0 88 M It also inhibits Uch-L3 with lower potency (IC50 25 M) In neuronal systems Uch-L1 inhibition by LDN 57444 results in reduced long-term potentiation and basal synaptic transmission effects resembling -amyloid-induced synaptic impairment Additionally in the rat insulinoma cell line INS 832/13 LDN 57444 triggers apoptosis characterized by increased caspase-3 activity and enhanced nuclear CHOP expression suggesting ER-stress associated cell death mechanisms This compound is utilized in neuroscience and cell biology research to investigate ubiquitin pathway modulation and related cellular responses
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LaMarKa Chemical Company Phenolphthalein Indicator (Methanol) 0.1%W/V (1 gpl), 0.5l
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Phenolphthalein Indicator (Methanol) 0.1%W/V (1 gpl), 0.5l Plastic Bottle
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Electron Microscopy Sciences Sodium Acetate 1% Aqueous 500 ML
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Used in Ehrlich's Hematoxylin , Mallory (1938); Ehrlich (1886), Nuclei.
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