Isotopically Labeled Compounds
Medchemexpress LLC L-Leucine-d2 | 362049-59-0 | MFCD01861592 | 133.19 | 5 MG
L-Leucine-d2 is the deuterium-labeled form of L-Leucine, an essential branched-chain amino acid (BCAA) known to activate the mTOR signaling pathway. This compound can be used as a tracer and as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS. Deuteration has the potential to influence the pharmacokinetic and metabolic profiles of drugs.
- Used as a tracer in quantitative analysis
- Functions as an internal standard for various analytical methods
- Activates the mTOR signaling pathway
- Potential to affect pharmacokinetic and metabolic profiles
Cayman Chemical PentadecnoIc AcId-d29 1mg
An internal standard for the quantification of pentadecanoic acid by GC- or LC-MS
Medchemexpress LLC Folinic acid-d4 calcium hydrate | 58-05-9 | 91.7% | 605.61 | 250 UG
Folinic acid-d4 calcium hydrate, also known as Leucovorin-d4 calcium hydrate, is a deuterated form of Folinic acid. It functions as a biological folic acid and is typically used as a rescue agent to reduce Methotrexate-induced toxicity. Stable heavy isotopes like deuterium are incorporated into drug molecules to serve as tracers for quantitation during drug development, which can also influence pharmacokinetic and metabolic profiles of drugs.
- Functions as a biological folic acid
- Reduces methotrexate-induced toxicity
- Can be used as a tracer
- Serves as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC D-Fructose-13C-1 | 117013-19-1 | 5 MG
D-Fructose-13C-1 is a 13C labeled D-Fructose, a naturally occurring monosaccharide found in plants. This compound is intended for research use only and can be utilized as a tracer and an internal standard for quantitative analysis. Stable heavy isotopes, such as carbon-13, are incorporated into drug molecules primarily as tracers for quantitation during drug development, impacting pharmacokinetic and metabolic profiles.
- Used as a tracer
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Cambridge Isotope Laboratories D-GLUCOSE (2-13C, 99%), 0.5 G, 105931-74-6
D-GLUCOSE (2-13C, 99%), 0.5 G, 105931-74-6
Medchemexpress LLC Meloxicam-13C,d3 | 1309936-00-2 | ≥99.9% | 1 MG
Meloxicam-13C,d3 is a deuterium labeled non-steroidal anti-inflammatory agent that inhibits COX activity, with IC50s of 0.49 μM for COX-2 and 36.6 μM for COX-1. It is for research use only and not sold to patients. Stable heavy isotopes have been incorporated into this drug molecule, primarily as a tracer for quantitation during drug development.
- Used as a tracer
- Functions as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Deuteration can impact pharmacokinetic and metabolic profiles of drugs
Cambridge Isotope Laboratories 25-HYDROXYVITAMIN D3 (6,19,19-D3,97%) 100 UG/ML IN ETHANOL, 1 ML, 140710-94-7
25-HYDROXYVITAMIN D3 (6,19,19-D3,97%) 100 UG/ML IN ETHANOL, 1 ML, 140710-94-7
Medchemexpress LLC Bis(2-ethylhexyl) phthalate (deuterated) | 352431-42-6 | 428.79 | C24D38O4 | 10 MG
DEHP-d38 is the deuterium-labeled form of bis(2-ethylhexyl) phthalate used as an analytical standard and tracer in mass spectrometry and quantitative studies. Supplied in a small research-scale package, it facilitates accurate quantification and recovery experiments where isotopic labeling improves analytical precision.
- Deuterium-labeled internal standard for mass spectrometry.
- Molecular formula C24D38O4, molecular weight 428.79, CAS 352431-42-6.
- Liquid, colorless to light yellow appearance.
- Stable under recommended storage: -20°C for long-term; -80°C in solvent for short-term.
- Available in small research quantities, including 10 mg packages.
Medchemexpress LLC Piperidin-4-ol-d5 | 1219799-35-5 | 106.18 | 25 MG
Piperidin-4-ol-d5 is a deuterium labeled variant of Piperidin-4-ol. It incorporates stable heavy isotopes of hydrogen, carbon, and other elements. This compound is primarily utilized as a tracer for quantitation during the drug development process, offering unique advantages due to deuteration's potential to influence the pharmacokinetic and metabolic profiles of pharmaceutical compounds.
- Deuterium labeled compound for specialized research.
- Contains stable heavy isotopes for precise quantitation.
- Effective as a tracer in drug development studies.
- May impact drug pharmacokinetics and metabolism.
Cambridge Isotope Laboratories GLUTARIC ACID (2,2,4,4-D4, 98%), 5 G, 19136-99-3
GLUTARIC ACID (2,2,4,4-D4, 98%), 5 G, 19136-99-3
Cambridge Isotope Laboratories HEXANOIC ACID (METHYL-D3, 98%), 0.5 G
HEXANOIC ACID (METHYL-D3, 98%), 0.5 G
Cayman Chemical CnaglIflozIn-d4 1mg
An internal standard for the quantification of canagliflozin by GC- or LC-MS
Medchemexpress LLC Fmoc-Pro-OH-13C5,15N | 1217452-48-6 | 343.33 | 50 MG
Fmoc-Pro-OH-13C5,15N is a 15N-labeled and 13C-labeled Fmoc-Pro-OH. Fmoc-Pro-OH is a proline derivative. Stable heavy isotopes have been incorporated into drug molecules for quantitation during the drug development process.
- Used as tracers for quantitation during drug development
- Deuteration has potential to affect pharmacokinetic and metabolic profiles of drugs
Medchemexpress LLC Tcep-d16 hydrochloride | 1174025-33-2 | 97.0% | 302.75 | 5 MG
TCEP-d16 (hydrochloride) is the deuterium labeled TCEP hydrochloride. TCEP hydrochloride (Tris(2-carboxyethyl)phosphine hydrochloride) is a non-thiol reducing agent that is more stable and produces a faster S-S reductive reaction than other chemical reductants. TCEP hydrochloride is a trialkylphosphine, selectively reduces protein disulfides without altering the properties or interacting with thiol-directed agents in the reaction mixture. TCEP hydrochloride is also a commonly used reducing agent in the DNA/AuNP chemistry.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC Thymine-d4-1 | 156054-85-2 | 99.5% | 130.14 | 10 MG
Thymine-d4-1 is a deuterium-labeled version of Thymine, one of the four nucleobases found in DNA. Thymine can be a target for the actions of 5-fluorouracil (5-FU) in cancer treatment, with a Km of 2.3 μM. This product is intended for research use only and is not sold to patients.
- Can be used as a tracer.
- Can serve as an internal standard for quantitative analysis using techniques such as NMR, GC-MS, or LC-MS.
- Stable heavy isotopes like deuterium have been incorporated into drug molecules for quantitation during drug development, with deuterium specifically noted for its potential to influence pharmacokinetic and metabolic profiles of drugs.