Isotopically Labeled Compounds
Medchemexpress LLC D-Alanine-d3 | 177614-69-6 | 99.31% | 92.11 | 5 MG
D-Alanine-d3 is the deuterium labeled D-Alanine. D-Alanine is a weak GlyR (inhibitory glycine receptor) and PMBA agonist, with an EC50 of 9 mM for GlyR. It can be used as a tracer and as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Used as a tracer
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC Nitrendipine-d5 | 2469554-26-3 | 99.8% | 100 UG
Nitrendipine-d5 is a deuterium-labeled analog of Nifedipine and a dihydropyridine calcium channel blocker. It has been studied for its ability to induce apoptosis, demonstrate antihypertensive and anticancer effects, and block withdrawal symptoms.
- Functions as a dihydropyridine calcium channel blocker
- Induces apoptosis
- Exhibits antihypertensive effects
- Blocks alcohol and morphine withdrawal symptoms
- Reduces right ventricular hypertrophy and pulmonary vascular changes
- Demonstrates anticancer effects on neuroblastoma
- Can be used as a tracer
- Serves as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC Creatinine-d5 | 60-27-5 | 99.9% | 5 MG
Creatinine-d5 is the deuterium labeled version of Creatinine, a breakdown product of creatine phosphate found in muscle. It is typically produced at a consistent rate by the body. Intended for research use only, this compound serves as a tracer and internal standard in analytical techniques.
- Deuterium labeled version of creatinine
- Can be used as a tracer
- Functions as an internal standard for quantitative analysis
- Suitable for techniques like NMR, GC-MS, or LC-MS
- May influence pharmacokinetic and metabolic profiles of drugs
- For research use only
Medchemexpress LLC Paroxetine-d4 hydrochloride | 2714485-95-5 | 99.2% | 1 MG
Paroxetine-d4 hydrochloride is a deuterium-labeled version of Paroxetine hydrochloride, a potent selective serotonin-reuptake inhibitor used as an antidepressant. It has GRK2 inhibitory ability with an IC50 of 14 μM and is suitable for research on depressive disorders. Deuterium-labeled drug molecules are used as tracers for quantitation during drug development and can influence pharmacokinetic and metabolic profiles.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC D-Glucose-d4 | 478529-49-6 | 99.0% | 50 MG
D-Glucose-d4 is the deuterium-labeled form of D-Glucose, an important monosaccharide and carbohydrate in biology. It serves as a critical signaling molecule and component of general metabolism. This compound can be utilized as a tracer and as an internal standard for quantitative analysis methods like NMR, GC-MS, or LC-MS.
- Used as a tracer.
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Deuteration has the potential to affect the pharmacokinetic and metabolic profiles of drugs.
Medchemexpress LLC Roxithromycin-d7 | 80214-83-1 | 98.3% | 1 MG
Roxithromycin-d7 (RU-28965-d7) is the deuterium-labeled version of Roxithromycin (HY-B0435), a semi-synthetic macrolide antibiotic. It is intended for research use only and is not sold to patients. Deuterium substitution, as seen in Roxithromycin-d7, has the potential to influence the pharmacokinetic and metabolic profiles of drugs.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC D-Sorbitol-13C | 287100-73-6 | 98.0% | 5 MG
D-Sorbitol-13C is the 13C labeled D-Sorbitol, a six-carbon sugar alcohol used as a sugar substitute. It functions as a stabilizing excipient, isotonicity agent, sweetener, humectant, thickener, and dietary supplement.
- Tracer
- Internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC Ketorolac-d5 | 1215767-66-0 | 98.8% | 5 MG
Ketorolac-d5 is a deuterium labeled Ketorolac. Ketorolac is a non-steroidal anti-inflammatory agent, acting as a nonselective COX inhibitor, with IC50s of 20 nM for COX-1 and 120 nM for COX-2.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Store powder at -20°C for 3 years; 4°C for 2 years.
- Store in solvent and stock solution at -80°C for 6 months; -20°C for 1 month.
Medchemexpress LLC Latanoprost-d4 | 130209-82-4 | 98.0% | 500 UG
Latanoprost-d4 is the deuterium-labeled Latanoprost, a prostaglandin F2α analogue and an agonist for the FP prostanoid receptor, which lowers intraocular pressure (IOP). It serves as a tracer and an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS. Deuteration has the potential to affect the pharmacokinetic and metabolic profiles of drugs, offering valuable insights in research.
- Deuterium labeled compound
- Prostaglandin F2α analogue
- Agonist for FP prostanoid receptor
- Lowers intraocular pressure (IOP)
- Useful as a tracer
- Functions as an internal standard for quantitative analysis
- Can affect pharmacokinetic and metabolic profiles of drugs
Medchemexpress LLC Fulvestrant-d5 | 129453-61-8 | 99.66% | 611.80 | 1 MG
Fulvestrant-d5 (ICI 182780-d5) is an isotope of Fulvestrant and a potent estrogen receptor (ER) antagonist. It effectively inhibits the growth of ER-positive MCF-7 cells and induces autophagy, demonstrating antitumor efficacy. This compound serves as a valuable tool for various analytical applications.
- Used as a tracer
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Contains stable heavy isotopes for quantitation during drug development
Sigma Aldrich Fine Chemicals Biosciences Sodium carbonate-13C 99 atom % 13C | 93673-48-4 | MFCD00148872 | 1G
Sodium carbonate-13C 99 atom % 13C | Mol Wt: 106.98 | 93673-48-4 | MFCD00148872 | 1G
Sigma Aldrich Fine Chemicals Biosciences Carbonyl-13C sulfide <5 atom % 18O, 99 atom % 13C | 6142-96-7 | MFCD00143929 | 250ML
Carbonyl-13C sulfide <5 atom % 18O, 99 atom % 13C | Mol Wt: 61.07 | 6142-96-7 | MFCD00143929 | 250ML
Medchemexpress LLC Alanine-2,3,3,3-d4 | 53795-92-9 | MFCD00084108 | 99.8% | 93.12 | C3H3D4NO2 | 100 MG
Alanine-2,3,3,3-d4 is a deuterium-labeled alanine used as a stable-isotope tracer and internal standard for research and analytical workflows. It supports accurate quantitation and method development in biochemical and pharmacokinetic studies, dissolves readily in water, and is supplied with recommended storage conditions for long-term stability.
- Deuterium-labeled alanine for tracer and internal standard use.
- High purity (≈99.8%) suitable for quantitative analysis.
- Soluble in water (≥ 50 mg/mL) for straightforward sample preparation.
- Stable as a powder under frozen storage for long-term use.
- Compatible with NMR, GC-MS, and LC-MS analytical methods.
Medchemexpress LLC Alanine-2,3,3,3-d4 | 53795-92-9 | MFCD00084108 | 99.8% | 93.12 g/mol | C3H3D4NO2 | 50 MG
Alanine-2,3,3,3-d4 is a deuterium-labeled alanine used as a stable isotope standard for analytical and biochemical applications. Supplied as a powder in multiple package sizes, it is suitable for mass spectrometry, nuclear magnetic resonance (NMR), isotope-dilution quantitation, and metabolic tracing. High isotopic and chemical purity, together with available documentation, supports reproducible analytical workflows.
- High isotopic purity (deuterium-labeled) for accurate internal standard use.
- High chemical purity for reliable analytical results.
- Available in small, research-scale quantities to minimize sample waste.
- Supplied with datasheet, certificate of analysis, and safety data sheet for quality and safety documentation.
- Stable under recommended storage conditions to preserve compound integrity.