Isotopically Labeled Compounds
Medchemexpress LLC 2-aminohexane-d6 | 1219802-28-4 | MFCD11983513 | 97.9% | 107.227 | CH3CH2CH2CD2CD(NH2)CD3 | 1mg
2-Aminohexane-d6 is the deuterium labeled 2-Aminohexane[1]
![Medchemexpress LLC Glycine-2,2-d2, N-[(1,1-dimethylethoxy)carbonyl]- | 42492-65-9 | 98.0% | 177.19 g/mol | C7H11D2NO4 | 100mg](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000268122.png-250.jpg)
Medchemexpress LLC Glycine-2,2-d2, N-[(1,1-dimethylethoxy)carbonyl]- | 42492-65-9 | 98.0% | 177.19 g/mol | C7H11D2NO4 | 100mg
Boc-Glycine-d2 is the deuterium labeled Boc-Glycine[1]
Medchemexpress LLC Methoxyamine-d3 hydrochloride | 110220-55-8 | 99.5% | 86.54 g·mol^-1 | CH3D3ClNO | 100mg
Methoxyamine-d3 (O-Methylhydroxylamine-d3) hydrochloride is the deuterium labeled Methoxyamine hydrochloride Methoxyamine hydrochloride is an orally active and potent base excision repair (BER) inhibitor[1]
Medchemexpress LLC Ivacaftor-d9 | 1413431-07-8 | 99.8% | 401.55 g/mol | C24H19D9N2O3 | 5 MG
Ivacaftor-d9 is a deuterated analogue of ivacaftor used as a research CFTR potentiator. Supplied as a high-purity solid in a 5 mg pack, it is intended for analytical and pharmacological studies including mass spectrometry and metabolic stability experiments.
- Deuterated analogue of ivacaftor for research applications.
- CFTR potentiator activity used in cystic fibrosis research.
- High purity suitable for analytical assays and bioanalytical work.
- Solid form, convenient for storage and handling.
- Useful as an isotopic internal standard for mass spectrometry.
- Packaged in a small 5 mg quantity for experimental use.
Medchemexpress LLC Dibutyl phthalate-d22 | 358731-15-4 | MFCD01861629 | 99.0% | 300.48 | C16D22O4 | 10mg
Dibutyl phthalate-d22 is the deuterium labeled Dibutyl phthalate[1] Dibutyl phthalate is a commonly used plasticizer commonly found in some food packaging materials personal care products and the coating of oral medications May cause toxicity and adverse neurobehavioral effects[2][3][4]
Medchemexpress LLC 5-(methyl-13C)pyrimidine-2,4(1H,3H)-dione-1,3-15N2 | 99.9% | 129.09 | C413CH615N2O2 | 5mg
Thymine-15N2 13C is the 13C and 15N labeled Thymine (HY-W010450) Thymine is one of the four nucleobases in the nucleic acid of DNA and can be a target for actions of 5-Fluorouracil (HY-90006) in cancer treatment with a Km of 2 3 M[1]
Medchemexpress LLC Clemizole-d4 | 442-52-4 | 99.8% | 329.86 | 1 MG
Clemizole-d4 is a deuterium labeled Clemizole. Clemizole is an H1 histamine receptor antagonist that has been found to substantially inhibit HCV replication.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC Tropicamide-d3 | 2673270-13-6 | 99.10% | 1 MG
Tropicamide-d3 is a deuterium labeled Tropicamide and a selective M4 muscarinic acetylcholine receptor antagonist. It produces short acting mydriasis (dilation of the pupil) and cycloplegia when applied as eye drops. Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules as tracers for quantitation during drug development. Deuteration can affect the pharmacokinetic and metabolic profiles of drugs.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC (R)-Amlodipine-d4 | 1346616-97-4 | 500 UG
(R)-Amlodipine-d4 is a deuterium-labeled form of (R)-Amlodipine. Stable heavy isotopes of hydrogen, carbon, and other elements are incorporated into drug molecules for use as tracers in drug development for quantitation. Deuteration has gained attention due to its potential to influence the pharmacokinetic and metabolic profiles of drugs.
- Deuterium-labeled form of (R)-Amlodipine
- Stable heavy isotopes for use as tracers
- Potential to influence pharmacokinetic and metabolic profiles of drugs
Medchemexpress LLC Acetophenone-d3 | 17537-31-4 | MFCD00064445 | 96.3% | 123.17 | C8H5D3O | 1g
Acetophenone-d3 is the deuterium labeled Acetophenone[1] Acetophenone is an organic compound with simple structure[2]
Medchemexpress LLC Ceftazidime-d5 (GR20263-d5) | 93.7% | 1 MG
Ceftazidime-d5 (GR20263-d5) is a deuterium-labeled antibiotic, specifically a version of Ceftazidime. Ceftazidime exhibits broad-spectrum activity against Gram-positive and Gram-negative aerobic bacteria, including Enterobacteriaceae (even β-lactamase-positive strains), and resists hydrolysis by most β-lactamases. Deuterium-labeled compounds, such as Ceftazidime-d5, are used as tracers for quantitative analysis during drug development, impacting pharmacokinetic and metabolic profiles.
- Deuterium-labeled version of Ceftazidime
- Exhibits broad-spectrum antibiotic activity
- Effective against Gram-positive and Gram-negative aerobic bacteria
- Active against Enterobacteriaceae, including β-lactamase-positive strains
- Resistant to hydrolysis by most β-lactamases
- Useful as a tracer
- Serves as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC Pentanoic acid, 5-(2,5-dimethylphenoxy)-2,2-di(methyl-d3)- | 1184986-45-5 | 98.7% | 1 MG
Gemfibrozil-d6 is the deuterium labeled form of Gemfibrozil, a known activator of PPAR-α and a lipid-lowering agent. It also functions as a nonselective inhibitor of several P450 isoforms. This compound is intended for research use only and serves as a valuable tool in scientific investigations, particularly as a tracer or an internal standard for quantitative analysis using techniques like NMR, GC-MS, or LC-MS.
- Deuterium labeled form of gemfibrozil
- Activator of PPAR-α
- Used as a lipid-lowering agent
- Nonselective inhibitor of several P450 isoforms
- Suitable as a tracer in research
- Ideal as an internal standard for quantitative analysis
- Incorporates stable heavy isotopes for pharmacokinetic studies
Medchemexpress LLC Benzene-2,3,5,6-d4-sulfonamide, 4-amino-N-(5-methyl-3-isoxazolyl)- | 1020719-86-1 | 99.3% | 5 MG
Sulfamethoxazole-d4 (Ro 4-2130-d4) is a deuterium-labeled version of Sulfamethoxazole, a sulfonamide antibiotic with broad antibacterial activity. It inhibits bacterial folate metabolism by competing with 4-Aminobenzoic acid (PABA) to affect dihydropteroate synthetase and dihydropteroate reductase. This compound is used in research for conditions such as urinary tract infections (UTIs), prostatitis, and bronchitis. Deuterium labeling incorporates stable heavy isotopes into the drug molecule, which can serve as a tracer for quantitation during drug development and potentially affect pharmacokinetic and metabolic profiles.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC Iohexol-d5 | 928623-33-0 | 100.0% | 1 MG
Iohexol-d5 is a deuterium-labeled derivative of Iohexol, a widely recognized radiographic contrast agent. This product is suitable for various imaging applications including myelography, computerized tomography, and MicroCT imaging. It also serves as a valuable tool in quantitative analysis as a tracer or internal standard for techniques like NMR, GC-MS, and LC-MS.
- Deuterium-labeled compound for research applications
- Functions as a radiographic contrast agent
- Useful as a tracer in analytical studies
- Can be used as an internal standard for quantitative analysis
- Suitable for myelography and computerized tomography