Isotopically Labeled Compounds
Medchemexpress LLC L-ascorbic acid-13c-2 | 1313730-17-4 | 95.0% | 1 MG
L-Ascorbic acid-13C-2 is the 13C labeled L-Ascorbic acid, an electron donor and endogenous antioxidant. It selectively inhibits Cav3.2 channels with an IC50 of 6.5 μM. This compound is suitable for use as a tracer or an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- 13C labeled L-ascorbic acid
- Acts as an electron donor and endogenous antioxidant
- Selectively inhibits Cav3.2 channels with an IC50 of 6.5 μM
- Suitable as a tracer or internal standard for quantitative analysis (NMR, GC-MS, LC-MS)
- Relevant to isotope-labeled compounds and metabolic flux analysis
- Application in cancer, neurological, and metabolic disease research
Medchemexpress LLC Metronidazole-d3 | 83413-09-6 | 99.97% | 5 MG
Metronidazole-d3 is deuterium labeled metronidazole, intended for research use only. This compound serves as a tracer and an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS. Stable heavy isotopes, like deuterium, are incorporated into drug molecules for quantitation during drug development and can affect pharmacokinetic and metabolic profiles.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC Moclobemide-d4 | 71320-77-9 | 99.0% | 100 UG
Moclobemide-d4 is a deuterium-labeled form of Moclobemide, a brain-penetrant and reversible monoamine oxidase (MAO-A) inhibitor. It has shown to up-regulate proliferation of hippocampal progenitor cells in chronically stressed mice and is used as a tracer or internal standard in quantitative analysis. Stable heavy isotopes, like deuterium, are incorporated into drug molecules for quantitation during drug development and can influence pharmacokinetic and metabolic profiles.
- Used as a tracer
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Affects pharmacokinetic and metabolic profiles of drugs
- Up-regulates proliferation of hippocampal progenitor cells in chronically stressed mice
Medchemexpress LLC Diphenylmethanol-d5 | 95450-78-5 | 189.26 | 50 MG
Diphenylmethanol-d5 is a deuterium labeled form of Diphenylmethanol. It is suitable for use as a tracer or as an internal standard in quantitative analysis methods such as NMR, GC-MS, or LC-MS. Deuteration of drug molecules has shown potential to influence their pharmacokinetic and metabolic profiles.
- Deuterium labeled Diphenylmethanol
- Suitable as a tracer
- Internal standard for quantitative analysis (NMR, GC-MS, LC-MS)
- Potential to affect pharmacokinetic and metabolic profiles of drugs
Medchemexpress LLC HMMNI-d3 (hydroxy dimetridazole-d3) | 1015855-78-3 | 160.15 | 5 MG
HMMNI-d3 (Hydroxy Dimetridazole-d3) is a deuterium-labeled variant of HMMNI (Hydroxy dimetridazole), which itself is a hydroxy metabolite of Dimetridazol. Dimetridazole belongs to the nitroimidazole class of agents known for combating protozoan infections. HMMNI-d3 is intended for research use only. Deuteration can potentially affect the pharmacokinetic and metabolic profiles of drugs.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC Diflunisal-d3 | 1286107-99-0 | 99.7% | 253.22 | 2.5 MG
Diflunisal-d3 is the deuterium labeled form of Diflunisal, a salicylate derivative with nonsteroidal anti-inflammatory and uricosuric properties. It acts as a Cyclooxygenase (COX) inhibitor and is used as an analgesic and in rheumatoid arthritis patients. This compound is intended for research use only.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Stable heavy isotopes are incorporated for quantitation during drug development.
- Deuteration may influence pharmacokinetic and metabolic profiles of drugs.
Medchemexpress LLC γ-Tocopherol-d4 | 1329652-13-2 | 1 MG
γ-Tocopherol-d4 is a deuterium-labeled form of γ-Tocopherol. The unlabeled compound, γ-Tocopherol (D-γ-Tocopherol), is recognized as a potent inhibitor of cyclooxygenase (COX) and is a naturally occurring form of Vitamin E. It is found in various plant seeds, including corn oil and soybeans. This compound is known for its anti-inflammatory properties and its anti-cancer activity.
- Deuterium-labeled compound.
- Acts as a potent cyclooxygenase (COX) inhibitor.
- Is a naturally occurring form of vitamin E.
- Demonstrates anti-inflammatory effects.
- Exhibits anti-cancer activity.
- Utilized as a tracer in research.
- Serves as an internal standard for quantitative analysis using techniques such as NMR, GC-MS, or LC-MS.
- Deuterium substitution can influence the pharmacokinetic and metabolic profiles of pharmaceutical compounds.
Cambridge Isotope Laboratories TAURINE (13C2, 99%; 15N, 98%), 0.01 G
TAURINE (13C2, 99%; 15N, 98%), 0.01 G
Cambridge Isotope Laboratories TRIOLEIN (1,1,1-13C3, 99%), 0.5 G, 82005-46-7
TRIOLEIN (1,1,1-13C3, 99%), 0.5 G, 82005-46-7
Cambridge Isotope Laboratories 1-IODOBUTANE (D9, 98%), 5 G, 59012-24-7
1-IODOBUTANE (D9, 98%), 5 G, 59012-24-7
Cayman Chemical Deoxycholic Acid, Purity: ≥95%, CAS: 83-44-3, 5 g
A secondary bile acid; inhibits TCA-induced spore germination in seven C. difficile strains at 0.2% v/v; inhibits growth and decreases the cytotoxicity of C. difficile culture supernatants to Vero cells at 0.02% v/v; inhibits ionizing radiation-induced p53-dependent transcription in a reporter assay using HCT116 cells at 200 µM; fecal and intestinal tissue levels are increased in a rat model of high-fat diet-induced obesity compared with rats fed a normal diet; increased serum levels have been found in patients with colorectal cancer
Cayman Chemical L-Threonine-d2, Purity: ≥99% deuterated forms (d1-d2), CAS: 1202936-45-5, 25 mg
An internal standard for the quantification of L-threonine by GC- or LC-MS
Medchemexpress LLC Metolazone-d7 | 2714484-71-4 | 99.9% | 5 MG
Metolazone-d7 is deuterium-labeled Metolazone, primarily used to treat congestive heart failure and high blood pressure. Stable heavy isotopes have been incorporated into this drug molecule for use as tracers in drug development, with deuteration potentially affecting pharmacokinetic and metabolic profiles.
- Molecular weight: 372.88
- Formula: C16H9D7ClN3O3S
- Unlabeled CAS: 17560-51-9
- Appearance: Solid
- Color: White to off-white
- Shipped at room temperature (continental US)
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Solubility in DMSO: ≥ 100 mg/mL
- Solubility in H2O: 0.67 mg/mL (requires ultrasonic)
- Storage (powder): -20°C for 3 years, 4°C for 2 years
- Storage (in solvent): -80°C for 6 months, -20°C for 1 month
Cambridge Isotope Laboratories L-Proline-N-Fmoc (13C5 99% 15N 99%) 1 g
L-Proline-N-Fmoc (13C5 99% 15N 99%) 1 g
Cayman Chemical Balsalazide-d4, Purity: ≥99% deuterated forms (d1-d4), 1 mg
An internal standard for the quantification of balsalazide by GC- or LC-MS