Isotopically Labeled Compounds
![Revvity Health Sciences Inc Taurocholic Acid, [<sup>3</sup>H(G)]-, 250µCi (9.25MBq)](https://assets.fishersci.com/TFS-Assets/CCG/product-images/509051004.jpg-250.jpg)
Revvity Health Sciences Inc Taurocholic Acid, [3H(G)]-, 250µCi (9.25MBq)
Taurocholic Acid, [3H(G)]-, 250µCi (9.25MBq)
Cayman Chemical BromocrIptIn-13C-d3 500ug
An internal standard for the quantification of bromocriptine by GC- or LC-MS
Cayman Chemical AldIcarb SulfoxIde 10mg
A metabolite and degradation product of aldicarb; reduces the number of male T. semipenetrans second-stage larvae that reach the third, fourth, and adult stages of development at 10 μg/ml; inhibits carboxylesterase and cholinesterase in zebrafish (IC50 = 10 μM for both)
Medchemexpress LLC Oxybutynin-d11 chloride | 1185151-95-4 | MFCD06658724 | 97.4% | 405.02 g·mol⁻¹ | C22H21D11ClNO3 | 10 MG
Oxybutynin-d11 chloride is a deuterium-labeled isotopologue of oxybutynin chloride intended as a stable-isotope reference standard for analytical, pharmacokinetic, and mass-spectrometry studies. Supplied as the chloride salt with defined molecular weight and high purity, it is suitable for use as an internal standard to improve quantitation and identification in LC-MS and GC-MS workflows.
- Deuterium-labeled internal standard for LC-MS and GC-MS.
- High chemical purity (97.4%) and isotopic labeling for reliable quantitation.
- Supplied as a chloride salt with known molecular formula and molecular weight for accurate calculations.
- Soluble in DMSO for convenient sample preparation.
Medchemexpress LLC Fulvestrant-d3 (ICI 182780-d3) | 129453-61-8 | 97.6% | 609.79 | 1 MG
Fulvestrant-d3 is a deuterium-labeled form of Fulvestrant (ICI 182780). Fulvestrant is a potent estrogen receptor (ER) antagonist with an IC50 of 9.4 nM and a pure antiestrogen. It acts as a GPR30 agonist and effectively inhibits the growth of ER-positive MCF-7 cells with an IC50 of 0.29 nM. Additionally, Fulvestrant induces autophagy and exhibits antitumor efficacy. This compound is intended for research use, specifically as a tracer and an internal standard for quantitative analysis methods like NMR, GC-MS, or LC-MS.
- Deuterium labeled Fulvestrant.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Stable heavy isotopes are incorporated for quantitation during drug development.
- Deuteration can potentially affect the pharmacokinetic and metabolic profiles of drugs.
Medchemexpress LLC Linuron-d6 | 1219804-76-8 | 99.8% | 5 MG
Linuron-d6 is the deuterium labeled Linuron, a phenylurea herbicide widely used to control the growth of grass and weeds in various agricultural crops and orchards. It functions as a photosystem II inhibitor and a competitive androgen receptor (AR) antagonist with a Ki of 100 μM. Linuron has been observed to exhibit reproductive toxicity in animals, acting as an endocrine disruptor. Stable heavy isotopes, such as deuterium, are incorporated into drug molecules as tracers for quantitation during the drug development process and have the potential to affect pharmacokinetic and metabolic profiles.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC Propazine-d14 | 1219802-87-5 | 99.0% | 5 MG
Propazine-d14 is a deuterium labeled Propazine, intended for research use only. It can serve as a tracer or an internal standard for quantitative analysis in various analytical techniques such as NMR, GC-MS, or LC-MS. Stable heavy isotopes like deuterium are incorporated into drug molecules primarily for quantitation during drug development and can also influence the pharmacokinetic and metabolic profiles of drugs.
- Can be used as a tracer.
- Acts as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Incorporates stable heavy isotopes to aid in drug development.
- Potential to affect pharmacokinetic and metabolic profiles of drugs.
Medchemexpress LLC Metolachlor-d6 | 1219803-97-0 | 99.56% | 5 MG
Metolachlor-d6 is the deuterium labeled Metolachlor, a pre-emergent selective, chloroacetanilide herbicide. It is used to control various annual grass and broadleaf weeds in corn and other crops, and is a chiral herbicide composed of four stereoisomers. Deuterium substitution can influence the pharmacokinetic and metabolic profiles of drugs.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Cambridge Isotope Laboratories Deuterium Oxide "100%" (D, 99.96%), Low Paramagnetic, 7789-20-0, MFCD00044636, 10 g plast
Chemical Formula: D2O, MW: 20.03, 99.5%, Synonyms: Deuterated water; Heavy water (D2O).
Medchemexpress LLC Sodium propionate-d5 | 202529-18-8 | 99.9% | 50 MG
Sodium propionate-d5 | 202529-18-8 | 99.9% | 50 MG
Medchemexpress LLC Nortriptyline hydrochloride | 894-71-3 | 99.98% | 100 MG
Nortriptyline hydrochloride is the main active metabolite of Amitriptyline, classified as a tricyclic antidepressant. It functions as a potent autophagy inhibitor and demonstrates anticancer effects, intended for research use only.
- Inhibits the Norepinephrine transporter (NET, SLC6A2)
- Reduces viability of bladder cancer cells
- Induces cell cycle arrest
- Induces apoptosis in bladder cancer cells
- Blocks reuptake of Norepinephrine more potently than Serotonin