Cell Function Reagents and Kits
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Filtered Search Results
![Medchemexpress LLC 5-chloro-N-[2-(4-hydroxysulfamoyl-phenyl)-ethyl]-2-methoxybenzamide | 2112809-98-8 | 98.4% | 384.83 | C16H17ClN2O5S | 10 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000226332.png-250.jpg)
Medchemexpress LLC 5-chloro-N-[2-(4-hydroxysulfamoyl-phenyl)-ethyl]-2-methoxybenzamide | 2112809-98-8 | 98.4% | 384.83 | C16H17ClN2O5S | 10 MG
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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JC-171 is a selective NLRP3 inflammasome inhibitor that blocks LPS/ATP-induced interleukin-1β (IL-1β) release from macrophages (IC50 = 8.45 μM). It has demonstrated activity in vitro and in vivo, including reduction of disease severity in mouse EAE models, and is supplied as a high-purity research chemical.
- Selective NLRP3 inflammasome inhibitor; IC50 = 8.45 μM for LPS/ATP-induced IL-1β release in J774A.1 macrophages.
- Shown to reduce disease severity in mouse EAE models and lower Th17 cell frequency.
- High purity (98.4%); molecular weight 384.83 g·mol⁻¹; formula C16H17ClN2O5S.
- Soluble ≥ 2.08 mg/mL in recommended vehicles for in vivo dosing.
- Available in small research pack sizes, including 10 mg.
- Recommended storage: powder at -20°C; prepared solutions at -80°C to limit freeze-thaw.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Abcam Mitochondrial Staining Kit - NIR Fluorescence - Cytopainter.
Mitochondrial Staining Kit - NIR Fluorescence - Cytopainter.
The product is subject to the following: Abcam Restricted Use Statement
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Apexbio Technology LLC RHOD 123 MITO MEM POT KIT 100T
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RHOD 123 MITO MEM POT KIT 100T APEXBIO TECHNOLOGIES
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Revvity Health Sciences Inc PhenoVue Fluor 647 - Live Cell Tubulin Stain
PhenoVue Fluor 647 - Live Cell Tubulin Stain
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Aat Bioquest Cal-590 AM (1 mg)
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Calcium measurement is critical for numerous biological investigations. This catalog is for 1 mg.
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Sartorius Fixable Viability Kit
The iQue Fixable Viability Kits are used to label viable from non-viable mammalian cells prior to downstream fixation and permeabilization which is required for intracellular cell staining. The dyes are cell membrane-impermeant that covalently label cell surface and intracellular amines resulting in dim surface staining of live cells and highly fluorescent staining of cells with compromised membranes. The staining is stable and the fluorescence is preserved following fixation and permeabilization.Key AdvantagesPreserve staining post fixation - Maintain fluorescence staining intensity to discriminate live and dead cells post fixation or permeabilization.Enable artifact-free analysis of intracellular targets- Monitor surface and intracellular marker expression simultaneously while reducing artifacts from dead cells.Save precious sample - Conserve samples for use in multiple downstream assays with only 20 L of cells required.
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Sartorius Fixable Viability Kit
The iQue Fixable Viability Kits are used to label viable from non-viable mammalian cells prior to downstream fixation and permeabilization which is required for intracellular cell staining. The dyes are cell membrane-impermeant that covalently label cell surface and intracellular amines resulting in dim surface staining of live cells and highly fluorescent staining of cells with compromised membranes. The staining is stable and the fluorescence is preserved following fixation and permeabilization.Key AdvantagesPreserve staining post fixation - Maintain fluorescence staining intensity to discriminate live and dead cells post fixation or permeabilization.Enable artifact-free analysis of intracellular targets- Monitor surface and intracellular marker expression simultaneously while reducing artifacts from dead cells.Save precious sample - Conserve samples for use in multiple downstream assays with only 20 L of cells required.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Aat Bioquest Fura-8 AM (1 mg)
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Although Fura-2 has become the preferred excitation-ratioable calcium indicator of choice it has certain limitations e.g. lower sensitivity than single wavelength calcium indicators such as Fluo-8 and Cal-520. This catalog is for 1 mg.
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Sigma Aldrich Fine Chemicals Biosciences Live Dead Cell Viability A
The Live-Dead Cell Viability Assay Kit is a quick and simple three-color assay to measure cell viability. The kit consists of Calcein-AM (stains live cells) Propidium Iodide (stains dead cells) and Hoechst 33342 (stains all cells). The kit has been optimized for 3D cell culture (spheroids human organoids and 3D matrices) and 2D cell culture (multiple cell types). The kit can be used for flow cytometry fluorescence microscopy and with fluorescence microplate readers. The kit determines viability of cells based on plasma membrane integrity and esterase activity. One kit contains reagents sufficient for 5 x 24-well plates or 12 x 96-well plates.boldAdvantages/bold 1. Tested and optimized for 3D cell culture Spheroid culture organoid culture 2D cell culture and flow cytometry.2. Easy to use and quick protocol.3. Stronger intensity of Calcein AM and Hoechst dyes compared to other products.Spectral PropertiesCalcein AM Ex/Em 490/515 nm (Green)Propidium Iodide Ex/Em 535/617 nm (Red)
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![Medchemexpress LLC 5-chloro-N-[2-(4-hydroxysulfamoyl-phenyl)-ethyl]-2-methoxy-benzamide | 2112809-98-8 | 98.4% | 384.83 g/mol | C16H17ClN2O5S | 50 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000226690.png-250.jpg)
Medchemexpress LLC 5-chloro-N-[2-(4-hydroxysulfamoyl-phenyl)-ethyl]-2-methoxy-benzamide | 2112809-98-8 | 98.4% | 384.83 g/mol | C16H17ClN2O5S | 50 MG
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Small and/or specialty supplier based on Federal laws and SBA requirements.
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JC-171 is a selective NLRP3 inflammasome inhibitor that reduces LPS/ATP-induced interleukin-1β (IL-1β) release from J774A.1 macrophages with an IC50 of 8.45 μM. It is supplied as a solid and as a DMSO solution for research use, with reported high purity and defined storage recommendations.
- Selective NLRP3 inflammasome inhibition in cell-based assays.
- Activity: IC50 8.45 μM for inhibition of IL-1β release.
- High reported purity: 98.41%.
- Molecular weight 384.83 g/mol; formula C16H17ClN2O5S.
- Available as solid quantities and as a 10 mM solution in DMSO.
- Storage recommendations provided for powder and in-solution stability.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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STEMCELL Technologies 7-AAD (7-Aminoactinomycin D), Size: 200 Tests
Cell viability dye (DNA-labeling dye)
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Promega Corporation MULTITOXFLUOR MULTIPLEX CYTOT
PRG9202 MULTITOXFLUOR MULTIPLEX CYTOT
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Biotium MAG-FURA-2 AM ESTER 1MG
MAG-FURA-2 AM ESTER 1MG
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Biotium 4-SULFORHODAMINE 101 CADAVERIN
4-SULFORHODAMINE 101 CADAVERIN
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Biotium INDO-1 AM ESTER 1MG
INDO-1 AM ESTER 1MG
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