Cell Culture Media, Supplements, and Reagents
Diagnocine LLC iPGell
Making a section of floating cells or 3D cultured cells (such as embryoid body, spheroid, etc) is burdensome work for researchers. Conventional methods are cytospin, smear slide, or agarose gel but these method gives damages to your cell sample as the cells are dried or heated during sample preparaiton. Moreover, for cytospin or smear slide method, you need to start again from sample preparation. iPGell will greatly help you to achieve this just by using two components. Cells can be rapidly jellified with unheated condition. Any toxic components affect to cells are not contained. Jellified sample can be soaked into fixation solution and then you can make a sample block (frozen / paraffin) like the way to make tissue block.
Medchemexpress LLC Magainin 1 | 108433-99-4 | 99.9% | 2409.85 | 500 UG
Magainin 1 is an antimicrobial and amphipathic peptide isolated from the skin of *Xenopus laevis*. It exhibits antibiotic activity against various Gram-negative and Gram-positive bacteria by interacting with acidic lipids to form an amphiphilic helix, leading to membrane leakage.
- Antimicrobial and amphipathic peptide
- Isolated from *Xenopus laevis* skin
- Exhibits antibiotic activity against Gram-negative and Gram-positive bacteria
- Interacts with acidic lipids through electrostatic and hydrophobic interactions
- Forms an amphiphilic helix
- Induces leakage of calcein from negatively-charged vesicles
- Binds to bovine brain phosphatidylserine sonicated vesicles
Medchemexpress LLC Erythromycin estolate | 3521-62-8 | 10 MM * 1 ML
Erythromycin estolate is a macrolide antibiotic and a derivative of Erythromycin used to treat a wide variety of bacterial infections. It is intended for research use only and not sold to patients. This compound can cause liver injury, primarily cholestatic hepatitis, due to its inhibitory effect on bile acid transport.
- Purity: 98.0%
- Molecular weight: 1056.39
- Formula: C52H97NO18S
- Functions as a macrolide antibiotic
- Used to treat bacterial infections
- Inhibits various flaviviruses including Zika, dengue, and yellow fever
- Inactivates viral particles by destroying viral membrane integrity
- Inhibits human BSEP with an IC50 of 4.1 μM
- Available as a solid, white to off-white in color
- Storage conditions: 4°C in sealed storage, away from moisture; in solvent: -80°C for 6 months or -20°C for 1 month
Medchemexpress LLC Vancomycin (hydrochloride) (Standard) | 1404-93-9 | 99.80% | 1485.71 | 100 MG
Vancomycin (hydrochloride) (Standard) | 1404-93-9 | 99.80% | 1485.71 | 100 MG
Medchemexpress LLC Benzathine benzylpenicillin (tetrahydrate) | 41372-02-5 | 1 ML
Penicillin G benzathine tetrahydrate, also known as Benzathine benzylpenicillin tetrahydrate, is an antibiotic effective against a wide range of bacterial infections. It has a molecular weight of 981.18 and a chemical formula of C₄₈H₆₄N₆O₁₂S₂. This product is typically an off-white to light yellow solid, intended for research use only.
- Effective against many bacterial infections
- Molecular weight of 981.18
- Chemical formula: C₄₈H₆₄N₆O₁₂S₂
- Appearance: solid, off-white to light yellow
- Purity: 99.02%
- Soluble in DMSO for in vitro applications
- Recommended storage as powder at -20°C for 3 years, 4°C for 2 years
- Recommended storage in solvent at -80°C for 6 months, -20°C for 1 month
Medchemexpress LLC VU0463271 | 1391737-01-1 | 99.8% | 382.50 | 1 ML
VU0463271 is a selective KCC2 antagonist, with an IC50 of 61 nM. It offers a potent and selective antagonist activity, making it suitable for various research applications.
- Selective KCC2 antagonist
- IC50 of 61 nM (KCC2)
- Greater than 100-fold selectivity versus the closely related Na-K-2Cl cotransporter 1 (NKCC1)
- No activity in a larger panel of GPCRs, ion channels, and transporters
- Rapidly cleared in vitro
Medchemexpress LLC Vascular endothelial growth factor receptor 2 (VEGFR-2), rat, recombinant, C-terminal His tag | >95.0% | 2 UG
Recombinant rat VEGFR-2 protein expressed in HEK293 cells with a C-terminal His tag. Supplied as a purified protein for in vitro biochemical and binding assays. Purity >95% by reducing SDS-PAGE and endotoxin <1 EU/μg (LAL). Follow manufacturer storage and reconstitution recommendations.
- Recombinant rat VEGFR-2 expressed in HEK293 cells.
- C-terminal His tag for detection and purification.
- Purity >95% as determined by reducing SDS-PAGE.
- Endotoxin <1 EU/μg, determined by LAL method.
- Suitable for biochemical and binding assays.
- Store at -20°C; aliquot for long-term storage.
Medchemexpress LLC Cefotaxime sodium | 64485-93-4 | 99.1% | C16H16N5NaO7S2 | 500 MG
Cefotaxime sodium is a β-lactamase stable cephalosporin and a third-generation cephalosporin antibiotic. It demonstrates broad-spectrum antibiotic activity against numerous Gram-positive and Gram-negative bacteria.
- Beta-lactamase stable cephalosporin
- Third-generation cephalosporin antibiotic
- Broad-spectrum antibiotic activity
- Active against numerous Gram-positive and Gram-negative bacteria
- Exhibits an MIC of 0.0625 mg/L for *V. vulnificus* CMCP6
Medchemexpress LLC Clarithromycin | 81103-11-9 | 747.95 | 1 ML
Clarithromycin is an inhibitor and agonist with broad-spectrum antimicrobial activity. It inhibits the CYP3A4-catalyzed triazolam alpha-hydroxylation with an IC50 (Ki) value of 56 (43) μM. Clarithromycin also significantly inhibits the hERG potassium current and affects autophagic flux by impairing the signaling pathway linking hERG1 and PI3K.
- Targets bacterial, cytochrome P450, and autophagy.
- Acts as an antibiotic.
- Relevant for research in infection and cancer.
- Inhibits CYP3A4-catalyzed triazolam alpha-hydroxylation.
- Significantly inhibits the hERG potassium current.
- Impairs autophagic flux by affecting the hERG1 and PI3K signaling pathway.
Medchemexpress LLC Ulipristal | 159811-51-5 | ≥98.0% | 433.58 | 50 MG
Ulipristal is a selective progesterone receptor modulator (SPRM) that binds to the progesterone receptor, inhibiting PR-mediated gene expression and interfering with progesterone activity in the reproductive system.
- Selective progesterone receptor modulator (SPRM)
- Binds to the progesterone receptor
- Inhibits PR-mediated gene expression
- Interferes with progesterone activity in the reproductive system
- May suppress the growth of uterine leiomyomatosis
- Can be used as emergency contraception by inhibiting or delaying ovulation and affecting endometrial tissue
Medchemexpress LLC Rac1 protein, human (sf9, GST) | >95.0% | 500 UG
Recombinant human RAC1 protein produced in Sf9 insect cells with an N-terminal GST tag. Supplied as a filtered formulation optimized for biochemical and structural assays, the protein shows >95% purity by reducing SDS-PAGE and is available in sizes including 500 μg.
- Expressed in Sf9 insect cells with N-terminal GST tag.
- Greater than 95% purity by reducing SDS-PAGE.
- Predicted molecular weight 47 kDa; observed ~44 kDa on SDS-PAGE.
- Formulated in 50 mM Tris, 100 mM NaCl, 1 mM GSH, 10% glycerol, pH 8.0.
- Supplied as a 0.22 μm filtered solution; avoid repeated freeze-thaw cycles.
- Store at -80°C; stable at -20°C for short-term storage.
- Suitable for biochemical assays, binding studies, and structural analysis.