Signal Transduction Reagents and Kits

Promega™ ADP-Glo™ Kinase Assay

One assay for all your kinase screening needs. The assay is well suited for measuring the effects of chemical compounds on the activity of many purified kinases, making it ideal for primary screening as well as kinase selectivity profiling.

Promega™ ADP-Glo™ Kinase Assay + CDK5/p25 Kinase Enzyme System

For measuring effects chemical compounds have on activity of broad range of purified kinases, making it ideal for both primary screening as well as kinase selectivity profiling

BD Phosflow™ Violet Fluorescent Cell Barcoding Kit

Provides reagents for successfully barcoding T cell subsets from human whole blood samples for studying phosphorylated protein induction in MAP Kinase and JAK/STAT signaling pathways

Promega™ ADP-Glo™ Kinase Assay + DNA-PK Kinase Enzyme System

For measuring effects chemical compounds have on activity of a broad range of purified kinases, making it ideal for both primary screening as well as kinase selectivity profiling

Promega™ ADP-Glo™ Kinase Assay + IKKβ Kinase Enzyme System

For measuring effects chemical compounds have on activity of a broad range of purified kinases, making it ideal for both primary screening as well as kinase selectivity profiling

Promega™ ADP-Glo™ Kinase Assay with PI:3PS

Highly sensitive detection assay with high specific activity

Promega™ ONE-Glo™ Assay

A reagent that is more robust and stable when reconstituted, and less aromatic than
standard reagents created with luciferin

Alfa Aesar™ K252c, 99%

Inhibits protein kinase C

Trypsin Inhibitor, chicken egg whites

Inhibits the pancreatic enzyme trypsin

Promega ALK2 Kinase Enzyme System, 10microg

ALK2 is a receptor serine/threonine kinase that is member of the ALK family and is upstream of signaling pathway involving the SMAD proteins especially SMAD1/5/8.

Alfa Aesar™ Sulindac Sulfide

Active metabolite of sulindac; inhibits cyclooxygenase-1

Promega TNIK Kinase Enzyme System, 10microg

Recombinant human TNIK (1-367) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. TNIK or TRAF2 and NCK-interacting kinase are characterized by N-terminal kinase and C-terminal GCK domains that serve a regulatory function.

Wortmannin, Penicillium funiculosum, ≥99%

Inhibitor of phosphatidylinositol 3-kinase

Promega CDK6/CyclinD3 Kinase Enzyme System, 10microg

Recombinant full-length human CDK6 and CyclinD3 were co-expressed by baculovirus in Sf9 insect cells using an N-terminal His tag on both proteins.

Promega IKK beta Kinase Enzyme System, 10microg

Full length recombinant human IKKβ was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.

U0126, ≥99%

Selective inhibitor of mitogen-activated protein kinases MEK-1 and MEK-2

Promega PI3K (p110alpha/p85alpha), 20ug, 200microl

The PI3K lipid kinase enzymes are used with ADP-Glo KInase Assay System and Lipid Kinase Substrates in a homogeneous, add-mix-read lipid kinase assay.

Alfa Aesar™ Ionomycin Calcium Salt, 99%

Highly selective and potent calcium ionophore

SB 202190, ≥99%

Inhibits p38 kinase activity in vivo through competition with ATP

Tioconazole, ≥98%

Potent inhibitor of cytochrome-P450

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