Signal Transduction Reagents and Kits

Promega™ ADP-Glo™ Kinase Assay

One assay for all your kinase screening needs. The assay is well suited for measuring the effects of chemical compounds on the activity of many purified kinases, making it ideal for primary screening as well as kinase selectivity profiling.

BD Phosflow™ Violet Fluorescent Cell Barcoding Kit

Provides reagents for successfully barcoding T cell subsets from human whole blood samples for studying phosphorylated protein induction in MAP Kinase and JAK/STAT signaling pathways

Promega™ ADP-Glo™ Kinase Assay + MST1 Kinase Enzyme System

For measuring effects chemical compounds have on activity of a broad range of purified kinases, making it ideal for both primary screening as well as kinase selectivity profiling

Promega™ ONE-Glo™ Assay

A reagent that is more robust and stable when reconstituted, and less aromatic than
standard reagents created with luciferin

U0126, ≥99%

Selective inhibitor of mitogen-activated protein kinases MEK-1 and MEK-2

Alfa Aesar™ Tropicamide, ≥99%

A muscarinic antagonist

Alfa Aesar™ TAPI-2

A hydroxamate-based inhibitor of MMPs and TACE

Alfa Aesar™ Sulindac Sulfide

Active metabolite of sulindac; inhibits cyclooxygenase-1

Promega™ Cell Permeable Inhibitors

Blocks the activation of MEK1, therefore inhibiting the subsequent phosphorylation and activation of MAP kinase

Alfa Aesar™ Ionomycin Calcium Salt, 99%

Highly selective and potent calcium ionophore

Alfa Aesar™ NF-kB Activation Inhibitor VI, BOT-64

A cell-permeable benzoxathiole compound that acts as an IKK-2 inhibitor

Alfa Aesar™ Ionomycin, 98%

Highly selective and potent calcium ionophore

Trypsin Inhibitor, soybeans

Inhibits the pancreatic enzyme trypsin

Promega™ Protein Kinase C Activator

An inactive analogue of and negative control for phorbol 12-myristate 13-acetate (PMA), which is also known as 12-O-tetradecanoylphorbol 13-acetate (TPA)