Signal Transduction Reagents and Kits

BD Phosflow™ Violet Fluorescent Cell Barcoding Kit

Provides reagents for successfully barcoding T cell subsets from human whole blood samples for studying phosphorylated protein induction in MAP Kinase and JAK/STAT signaling pathways

Promega™ ADP-Glo™ Kinase Assay

One assay for all your kinase screening needs. The assay is well suited for measuring the effects of chemical compounds on the activity of many purified kinases, making it ideal for primary screening as well as kinase selectivity profiling.

Promega™ ONE-Glo™ Assay

A reagent that is more robust and stable when reconstituted, and less aromatic than
standard reagents created with luciferin

Trypsin Inhibitor, soybeans

Inhibits the pancreatic enzyme trypsin

Promega™ ADP-Glo™ Kinase Assay + MST1 Kinase Enzyme System

For measuring effects chemical compounds have on activity of a broad range of purified kinases, making it ideal for both primary screening as well as kinase selectivity profiling

Alfa Aesar™ Tropicamide, ≥99%

A muscarinic antagonist

Alfa Aesar™ Ionomycin Calcium Salt, 99%

Highly selective and potent calcium ionophore

Promega PI3K (p110beta/p85alpha), 20ug, 200microl

The PI3K lipid kinase enzymes are used with ADP-Glo KInase Assay System and Lipid Kinase Substrates in a homogeneous, add-mix-read lipid kinase assay.

Promega HDAC-Glo Class IIa Assay, 10ml

The HDAC-Glo Class IIa and HDAC-Glo 2 Assays are single-reagent-addition homogeneous, luminescent assays that measure the relative activity of histone deacetylase (HDAC) Class IIa and Class I enzyme 2 from cells, extracts or purified enzyme sources.

Promega MLK2 Kinase Enzyme System, 10microg

Recombinant human MLK2 (1-446) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. MLK2 or mixed-lineage kinase 2 is a member of the serine/threonine kinase family, which activates MAPK8/JNK1 and MKK4/SEK1.

Promega P450-Glo CYP3A4 Assay, 50ml

The P450-Glo CYP3A4 Assay System provides a homogeneous, luminescent method for measuring CYP3A4 activity and the screening system contains a complete set of reagents for performing the assay.

Promega™ Cell Permeable Inhibitors

Blocks the activation of MEK1, therefore inhibiting the subsequent phosphorylation and activation of MAP kinase

U0126, ≥99%

Selective inhibitor of mitogen-activated protein kinases MEK-1 and MEK-2

Alfa Aesar™ NF-kB Activation Inhibitor VI, BOT-64

A cell-permeable benzoxathiole compound that acts as an IKK-2 inhibitor

Zolmitriptan

A serotonin 5HT1D-receptor agonist

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