11684

• Gene Symbol: PFN2
• Gene Name: profilin 2
• Gene Aliases: D3S1319E, PFL
• Chromosome Location: Chr.3: 149964904 - 149970954 on Build GRCh38
• UniGene ID: Hs.91747
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: PFN2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_002628.4	NP_002619.1	2	278
	NM_053024.3	NP_444252.1	2	278
GenBank mRNA	AF228738.1	-	2	180
	AK297915.1	-	2	246
	AK307227.1	-	2	221
	AK311780.1	-	2	228
	AK311782.1	-	2	183
	BC002964.1	-	2	194
	BC018049.1	-	2	246	4796198
	BC043646.1	-	2	435	5274799
	BC095444.1	-	2	219	30717207
	L10678.1	-	2	193

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Mouse: NM_019410, AJ272203, AK164145, AK132651, BC024363.

Panther Classification:

Molecular Function -

non-motor actin binding protein

Gene Ontology Categories:

Process(es)

negative regulation of epithelial cell migration
actin cytoskeleton organization
negative regulation of actin filament polymerization
positive regulation of actin filament polymerization
positive regulation of actin filament bundle assembly
positive regulation of ATPase activity
positive regulation of peptidyl-serine phosphorylation
protein stabilization
positive regulation of stress fiber assembly
negative regulation of ruffle assembly
regulation of synaptic vesicle exocytosis

Function(s)

adenyl-nucleotide exchange factor activity
actin monomer binding
protein binding
phosphatidylinositol-4,5-bisphosphate binding