5823

• Gene Symbol: MBTPS2
• Gene Name: membrane bound transcription factor peptidase, site 2
• Gene Aliases: BRESEK, IFAP, KFSD, KFSDX, OLMSX, S2P
• Chromosome Location: Chr.X: 21839538 - 21885423 on Build GRCh38
• UniGene ID: Hs.443490
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: MBTPS2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_015884.3	NP_056968.1	5, 6	861
GenBank mRNA	AF019612.1	-	5, 6	763
	AK292933.1	-	5, 6	768
	AK307143.1	-	1, 2	132
	AK312474.1	-	5, 6	694

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_001035007, XM_006256944.
This siRNA also targets the following transcripts in Mouse: NM_172307, AK148325, BC038343, AK164486.

Panther Classification:

Molecular Function -

metalloprotease, protease, protein modifying enzyme

Gene Ontology Categories:

Process(es)

cholesterol metabolic process
membrane protein intracellular domain proteolysis
response to endoplasmic reticulum stress
ATF6-mediated unfolded protein response
positive regulation of sequence-specific DNA binding transcription factor activity
positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress

Function(s)

metalloendopeptidase activity
metallopeptidase activity
metal ion binding