Biochemical Reagents
Apexbio Technology LLC Epidermal Growth Factor Receptor Peptide (985-996) 96249-43-3 5mg
Epidermal Growth Factor Receptor Peptide (985-996) (CAS 96249-43-3) corresponds to a C-terminal segment of the EGFR protein involved in receptor autophosphorylation EGFR a transmembrane receptor tyrosine kinase undergoes activation upon ligand binding triggering receptor dimerization and subsequent phosphorylation of specific tyrosine residues within its C-terminus including the 985-996 region This phosphorylation facilitates recruitment of SH2 domain-containing signaling proteins thereby initiating pathways such as MAPK Akt and JNK which regulate cell proliferation migration and adhesion This peptide serves as a useful research tool for elucidating EGFR-mediated signaling and studying kinase-substrate interactions in cellular models
Cayman Chemical AtrIal NatrIuretIc PeptID3 1mg
An atrial natriuretic peptide; a synthetic and truncated form of ANP; potently inhibits renin release from cultured renal juxtaglomerular cells (Ki = 10 pM) in a cGMP-dependent manner; dose-dependently decreases MAP and arterial plasma renin activity and increases fractional sodium and calcium excretion, urine volume, and glomerular filtration rate in conscious dogs (maximum effect = 200 pM)
Cayman Chemical JWH 018 2naphthylN 2 2dI 5mg
Differs structurally from JWH 018 by having the naphthyl group attached at the 2' position and 2,2-dimethylpropyl in place of the pentyl chain
Biolegend LEGENDplex™ Human C-Peptide Capture Bead A8, 13X
LEGENDplex™ Human C-Peptide Capture Bead A8, 13X Reactivity: Human; Apps: Multiplex - Component; Size: 100 tests (270 uL)
ABclonal Technology SIRT2 Rabbit pAb
This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined, however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Several transcript variants are resulted from alternative splicing of this gene.
CPC Scientific H-Arg-Lys-Ala-Ala-Pro-Ala-Thr-Gly-Gly-Val-Lys(Me3)-Lys-Pro-His-Arg-Tyr-Arg-Pro-Gly-Thr-Val-Lys(Biotin)-OH (trifluoroacetate salt) 0.25MG
This peptide is the fragment of Histone H3 (26-46) with a tri-methylated Lys36. The C-terminal contains a biotinylated Lys. It is associated with RNA polymerase II (Pol II) elongation in Saccharomyces cerevisiae.ONE-LETTER SEQUENCE: RKAAPATGGV-K(Me3)-KPHRYRPGTV-K(BIOTIN)MOLECULAR FORMULA: MOLECULAR WEIGHT:2644.1STORAGE CONDITIONS: -20 5CRESEARCH AREA: MiscellaneousREFERENCES: Baetz, K. et al. Mol Cell Biol 26, 7871 (2006)
Cayman Chemical 1 24dIhydroxy VItamIn D3hy 5mg
An analog of 1,24-dihydroxy vitamin D3 which, when used in a 4 μg/g ointment, suppresses psoriasis; inhibits the growth of both normal and psoriatic human keratinocytes (IC50 ~ 10 nM) via the vitamin D receptor; suppresses the production of RANTES and IL-8 by human dermal fibroblasts
![Medchemexpress LLC Benzamide, n-[(3,4-dichlorophenyl)methyl]-5-(6-fluoro-2-methyl-3-pyridinyl) trifluoroacetate | 2749300-35-2 | 98.0% | 612.40 g·mol-1 | C27H23Cl2F4N5O3 | 5 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000263697.png-250.jpg)
Medchemexpress LLC Benzamide, n-[(3,4-dichlorophenyl)methyl]-5-(6-fluoro-2-methyl-3-pyridinyl) trifluoroacetate | 2749300-35-2 | 98.0% | 612.40 g·mol-1 | C27H23Cl2F4N5O3 | 5 MG
WDR5-IN-4 TFA is a small-molecule inhibitor of the WIN site of WD repeat-containing protein 5 (WDR5), supplied as the trifluoroacetate salt for research use. Provided in a 5 mg pack, it features high reported purity and defined molecular properties suitable for biochemical and cellular studies of WDR5-dependent epigenetic regulation.
- High reported purity (98.0%).
- Supplied as the trifluoroacetate (TFA) salt.
- Molecular weight 612.40 g·mol-1.
- Molecular formula C27H23Cl2F4N5O3.
- Suitable for biochemical and cellular assays.
- Provided in a 5 mg pack for small-scale research.
CPC Scientific H-Cys-Thr-His-Gly-Ile-Arg-Pro-Val-Val-Ser-Thr-Gln-Leu-Leu-Leu-Asn-Gly-Ser-Leu-Ala-Glu-OH (trifluoroacetate salt) 1MG
This fragment with sequence homology to a domain of the external envelope glycoprotein (gp120) of the human immunodeficiency virus (HIV) is important for HIV infectivity and antibody neutralization.ONE-LETTER SEQUENCE: CTHGIRPVVSTQLLLNGSLAEMOLECULAR FORMULA: C95H162N28O30S1MOLECULAR WEIGHT:2208.57STORAGE CONDITIONS: -20 5C, CAS REGISTRY NUMBER: [113944-46-0], RESEARCH AREA: AntimicrobialREFERENCES: D.D.Ho et al., Science, 239, 1021 (1988)
CPC Scientific H-Tyr-DPen-Gly-(4Cl)Phe-DPen-OH (trifluoroacetate salt) 1MG
Highly selective ligand with high affinity for the delta-opioid receptor.SEQUENCE: H-Tyr-DPen-Gly-(4Cl)Phe-DPen-OH (trifluoroacetate salt)ONE-LETTER SEQUENCE: Y-DPen-G-(4Cl)Phe-DPenMOLECULAR FORMULA: C30H38N5O7S2Cl1MOLECULAR WEIGHT: 680.3STORAGE CONDITIONS: -20 5 CCAS REGISTRY NUMBER: SYNONYMS: RESEARCH AREA: PainREFERENCES:L.K. Vaughn et al., Life Sciences, 45, 1001 (1989)SKU(s): ENKP-005A, ENKP-005B
Bachem Mast Cell Degranulating (MCD) Peptide
Mast Cell Degranulating (MCD) Peptide, H-Ile-Lys-Cys-Asn-Cys-Lys-Arg-His-Val-Ile-Lys-Pro-His-Ile-Cys-Arg-Lys-Ile-Cys-Gly-Lys-Asn-NH2, 32908-73-9, C110H192N40O24S4, Mr 2587.25, 0.5mg. Peptide 401. The highly basic MCD peptide is present in small amounts in the venom of the European honeybee, Apis mellifera. At low doses, it causes mast cell degranulation and subsequent histamine release. At higher doses, it produces an anti-inflammatory effect, which may be beneficial in rheumatic and allergic diseases.
Cayman Chemical 14 15-EET methyl ester 50UG
An esterified version of (±)14(15)-EET; more stable for long-term storage and can be readily hydrolyzed to the free acid just before use; equipotent to (±)14(15)-EET in inducing relaxation of isolated bovine coronary arteries precontracted by U-46619
Cayman Chemical 2 3-dInor Thromboxn B2 50ug
An endogenous CB neurotransmitter that binds to both CB1 and CB2 receptors
Cayman Chemical SynthetIc MoracIn M 25mg
A polyphenol with diverse biological activities; inhibits PDE4D2 and PDE4B2 (IC50s = 1.9 and 4.5 µM, respectively); induces cell death in P388 cells (IC50 = 24.8 µM); inhibits IL-1β-induced increases in the levels of phosphorylated ERK and JNK in A549 cells at 30 or 50 µM; inhibits LPS-induced increases in NO and iNOS levels in MH-S macrophages at 50 and 60 µM, respectively; inhibits LPS-induced increases in the number of neutrophils, alveolar macrophages, and dendritic cells in BALF, the thickness of alveolar walls, and the levels of NF-κB in the lungs in a rat model of acute lung injury at 60 mg/kg
AnaSpec Substance P[RPKPQQFFGLM-NH2] | MW 1347.7 | (1 mg)
Substance P[RPKPQQFFGLM-NH2]; MW 1347.7; (1 mg)