Carbohydrates
Medchemexpress LLC SN-38 glucuronide | 121080-63-5 | 99.5% | 568.53 | 10 MM * 1 ML
SN-38 glucuronide is an inactive metabolite of the anticancer active molecule Irinotecan and has toxic effects on the gastrointestinal tract. Irinotecan is a topoisomerase I inhibitor used for researching colon and rectal cancer. SN-38 glucuronide can serve as a substrate for gut microbial β-glucuronidase enzymes, which remove the glucuronic acid moiety to reactivate SN-38, thereby increasing its toxic effects on the gut. SN38-G is the glucuronidated metabolite of SN38, and cells capable of metabolizing SN38 to SN38-G are more resistant to extracellular SN38 than cells lacking this capability.
- Inactive metabolite of Irinotecan
- Used for research on colon and rectal cancer
- Can be reactivated by gut microbial β-glucuronidase enzymes
Medchemexpress LLC Integrin alpha 6 bet 100ug
Integrin alpha 6 beta 1 Protein Human (HEK293 Flag-His) is the recombinant human-derived Integrin alpha 6 beta 1 protein expressed by HEK293 with C-His C-Flag labeled tag has molecular weight of 110 130 kDa respectively
Medchemexpress LLC Mosapride citrate dihydrate | 636582-62-2 | 99.6% | 25 MG
Mosapride citrate dihydrate is a gastroprokinetic agent that acts as a 5-hydroxytryptamine4 receptor agonist. It has been extensively used in research related to various gastrointestinal disorders. This compound also potently inhibits Kv4.3 in a concentration-dependent manner, with an IC50 value of 15.2 μM. In vivo, it specifically stimulates upper gastrointestinal motility.
- Acts as a 5-hydroxytryptamine4 receptor agonist
- Used in research for gastrointestinal disorders
- Potently inhibits Kv4.3
- Selectively stimulates upper gastrointestinal motility in vivo
Medchemexpress LLC Diethylstilbestrol-d8 | 91318-10-4 | MFCD01074086 | 99.7% | C18H12D8O2 | 10MG
Diethylstilbestrol-d8 is the deuterium-labeled analogue of diethylstilbestrol supplied as a high-purity powder for research and analytical use. It is intended as a stable isotope internal standard for LC-MS, pharmacokinetic studies, and quantitative assays where mass differentiation from the parent compound is required.
- High isotopic purity suitable for mass spectrometry internal standard.
- Purity 99.7% as supplied.
- Molecular formula C18H12D8O2 and molecular weight 276.40.
- Recommended solvent: DMSO, 50 mg/mL with ultrasonic and warming.
- Storage: powder -20°C (3 years) or 4°C (2 years); in solvent -80°C (6 months) or -20°C (1 month).
- Supplied in small research pack sizes appropriate for analytical workflows.
Medchemexpress LLC IFN-beta Protein, Rhesus Macaque (HEK293, Fc) | ≥ 85% | Approximately 45-56 kDa | 50 UG
IFN-beta Protein is an immunomodulatory cytokine of the type 1 interferon family. It reduces joint inflammation by inhibiting the RANKL-c-Fos signaling pathway and regulates mitochondrial fission through STAT5, PGAM5, and Drp1 to rescue neurodegeneration. This specific product is a recombinant Rhesus Macaque-derived IFN-beta protein, expressed by HEK293, with a C-mFc labeled tag.
- Immunomodulatory cytokine of the type 1 interferon family.
- Reduces joint inflammation by inhibiting the RANKL-c-Fos signaling pathway.
- Regulates mitochondrial fission through STAT5, PGAM5, and Drp1 to rescue neurodegeneration.
Medchemexpress LLC Sodium zirconium cyclosilicate | 17141-74-1 | 95.0% | 10MG
Sodium zirconium cyclosilicate | 17141-74-1 | 95.0% | 10MG
Medchemexpress LLC Integrin alpha 8 bet 100ug
Integrin -8/ -1 coordinates the recruitment of mesenchymal cells during renal organogenesis and recognizes RGD sequences in ligands such as TNC FN1 SPP1 TGFB1 TGFB3 and VTN It plays a role in multiple cellular interactions critical for organogenesis including NPNT as a functional ligand in nephrogenesis Integrin alpha 8 beta 1 Protein Human (HEK293 His) is a recombinant protein dimer complex containing human-derived Integrin alpha 8 beta 1 protein expressed by HEK293 with C-His labeled tag Integrin alpha 8 beta 1 Protein Human (HEK293 His) has molecular weight of 120-140 kDa 100-120 kDa respectively
Medchemexpress LLC Integrin alpha 5 bet 10ug
ITGA5 is a multifunctional receptor that interacts with multiple ligands such as fibronectin fibrinogen PLA2G2A fibrillin-1 (FBN1) IL1B human metapneumovirus and soluble CD40LG ITGA5 recognizes RGD sequences and mediates cell adhesion through different binding sites Integrin alpha 5 beta 1 Protein Human (HEK293 Flag-His) is a recombinant protein dimer complex containing human-derived Integrin alpha 5 beta 1 protein expressed by HEK293 with C-Flag C-10 His labeled tag Integrin alpha 5 beta 1 Protein Human (HEK293 Flag-His) has molecular weight of 101 35 kDa
Medchemexpress LLC Integrin alpha X bet 10ug
Integrin -X/ -2 is a receptor for fibrinogen that recognizes GPR sequences It plays a key role in inflammatory responses particularly in monocyte adhesion and chemotaxis Integrin alpha X beta 2 Protein Human (HEK293 His) is a recombinant protein dimer complex containing human-derived Integrin alpha X beta 2 protein expressed by HEK293 with C-His labeled tag Integrin alpha X beta 2 Protein Human (HEK293 His) has molecular weight of 130-150 kDa (ITGAX) 85-96 kDa (ITGB2) respectively
![Medchemexpress LLC 2-((6-(4-chlorophenyl)-1-methyl-4H-triazolo[4,3-a]azepin-4-yl)methyl)-5-methyl-1,3,4-oxadiazole | 1588521-78-1 | 99.8% | 403.86 g/mol | C22H18ClN5O | 10MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000237008.png-250.jpg)
Medchemexpress LLC 2-((6-(4-chlorophenyl)-1-methyl-4H-triazolo[4,3-a]azepin-4-yl)methyl)-5-methyl-1,3,4-oxadiazole | 1588521-78-1 | 99.8% | 403.86 g/mol | C22H18ClN5O | 10MG
BET-BAY 002 is a research-grade small-molecule BET bromodomain inhibitor used in epigenetic and oncology research. It is supplied as a white to off-white solid (CAS 1588521-78-1) with a molecular weight of 403.86 g/mol and reported high purity for reliable experimental use. The compound dissolves readily in DMSO and has recommended storage conditions for long-term stability.
Medchemexpress LLC IFN-beta Rhesus Mac 50ug
IFN-beta Protein Rhesus Macaque (HEK293 Fc Solution) is the recombinant rhesus macaque-derived IFN-beta protein expressed by HEK293 with C-mFc tag
Medchemexpress LLC Bet bromodomain inhibitor | 1505453-59-7 | MFCD28144506 | 99.5% | 445.90 g/mol | C24H20ClN5O2 | 100 MG
BET bromodomain inhibitor is a small-molecule research compound that selectively inhibits BET family bromodomains, including BRD4, with reported biochemical potency (BRD4(1) IC50 = 14 nM). It is supplied as a solid (white to off-white) with high purity for preclinical laboratory use.
- Potent BRD4 inhibitor (IC50 = 14 nM).
- High purity (~99.5%).
- Solid, white to off-white powder.
- Recommended storage: powder -20°C (3 years) or 4°C (2 years).
- Available in small research quantities, including 100 MG packaging.
Medchemexpress LLC IL-18RAP Rhesus Mac 5ug | 5ug
IL-18 is a pleiotropic proinflammatory cytokine that is involved in induction of inflammatory mediators regulation of the cytotoxic activity of NK cells and T cells and differentiation and activation of both Th1 and Th2 cells IL-18 signals through its specific cell surface receptor IL-18R which comprises two subunits IL-18R and IL-18R beta IL-18 forms a signalling complex with the IL-18 receptor (R ) and (R ) chains at the plasma membrane which induces multiple inflammatory cytokines[2] IL-18R complex recruits the IL-1R- activating kinase and TNF- associated factor 6 which phosphorylates nuclear factor k - inducing kinase with subsequent activation of NF- k [3] IL-18R betaknockdown inhibits IL-18 driven tumor cell metastasis in C57/BL6 mice[4] IL-18RAP Protein Rhesus Macaque (HEK293 His) is a recombinant protein with a His label that consists of 357 amino acids (M1-R356) and is produced by HEK293 cells
Medchemexpress LLC Mac glucuronide linker-1 | 2222981-71-5 | 96.4% | 897.90 g/mol | C42H47N3O17S | 500 MG
MAC glucuronide linker-1 is a cleavable glucuronide-based linker developed for constructing antibody-drug conjugates (ADCs) in research applications. It is supplied as a solid with reported high purity and specific storage recommendations for stability.
- Cleavable glucuronide-based linker suitable for ADC construction.
- Reported purity 96.36% (typical).
- Molecular weight 897.90 g/mol.
- Chemical formula C42H47N3O17S.
- Supplied as a powder; multiple package sizes available.
- Recommended storage: 4°C under nitrogen; in solvent: -80°C (6 months), -20°C (1 month).
- For research use only; not for human therapeutic use.
Medchemexpress LLC BET-IN-14 | 2243669-93-2 | C30H37N7O2 | 5 MG
BET-IN-14 is an orally active pan BET inhibitor with an IC50 of 5.35 nM, demonstrating anti-cancer activity. It is intended for research use only.
- Orally active pan BET inhibitor
- Exhibits anti-cancer activity
- High purity (99.07%)
- Solid, light yellow to yellow appearance
- Soluble in DMSO (100 mg/mL)
- Effective against various cancer cell lines (average IC50: 174.7 nM)
- Inhibits tumor growth in MV-4-11 xenograft models