Carbohydrates
Medchemexpress LLC D-(+)-Trehalose-d14 | 2028292-31-9 | 356.38 | 5 MG
D-(+)-Trehalose-d14 is the deuterium labeled D-(+)-Trehalose. D-(+)-Trehalose, isolated from *Saccharomyces cerevisiae*, can be used as a food ingredient and pharmaceutical excipient.
- This compound can be used as a tracer.
- This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
Medchemexpress LLC D-(+)-Trehalose (standard) | 99-20-7 | 342.30 | 50 MG
D-(+)-Trehalose (Standard) is a laboratory chemical and analytical standard intended for research and analytical applications. It is used in the manufacture of various substances.
- For research use only
- Not fully validated for medical applications
Medchemexpress LLC Cimiracemoside D | 290821-39-5 | MFCD28411517 | 678.85 | 1 ML
Cimiracemoside D is a natural product isolated from Actaea racemosa, appearing as a white to off-white solid. It exhibits solubility in DMSO (100 mg/mL, 147.31 mM with sonication) and detailed protocols for preparing stock solutions and in vivo dissolution are available.
- Purity of 99.89%
- Isolated from Actaea racemosa
- Appears as a white to off-white solid
- Soluble in DMSO (100 mg/mL, 147.31 mM)
- Includes protocols for stock solution preparation
- Includes protocols for in vivo dissolution using various solvents
- Powder storage at -20°C for 3 years, 4°C for 2 years
- In-solvent storage at -80°C for 2 years, -20°C for 1 year
Medchemexpress LLC D-GsMTx4 | 1209500-46-8 | 99.4% | 4095.84 | 500 UG
D-GsMTx4 is a spider peptide and the D enantiomer of GsMTx4. It functions as an inhibitor of the mechanosensitive ion channel Piezo2. It also inhibits [Ca2+]i elevation and the mTOR and PI3K-Akt signaling pathways. This compound has been used in research related to mechanical stress, chronic pain, and idiopathic pulmonary fibrosis, and inhibits mechanical allodynia and thermal hyperalgesia.
- Inhibits mechanosensitive ion channel Piezo2
- Decreases phosphorylation levels of proteins in mTOR and PI3K-Akt signaling pathways
- Inhibits mechanical stimulation-evoked calcium increases
- Significantly inhibits mechanical allodynia and thermal hyperalgesia
- Used in research for mechanical stress, chronic pain, and idiopathic pulmonary fibrosis
Medchemexpress LLC Platycodin D | 58479-68-8 | 1225.32 | 1 ML
Platycodin D is a saponin isolated from Platycodon grandiflorus. It acts as an activator of AMPKα and possesses anti-obesity properties. The WNT/β-catenin pathway mediates its anti-adipogenic effect.
Medchemexpress LLC D-(+)-Trehalose | 99-20-7 | 342.30 | 500 MG
D-(+)-Trehalose is an orally active disaccharide that exhibits anti-desiccant and cryopreservative activities. It functions as an osmolyte and stress protectant, aiding in carbon storage and transport. It can be utilized as a food ingredient and a pharmaceutical excipient.
- Orally active disaccharide
- Exhibits anti-desiccant and cryopreservative activities
- Functions as an osmolyte and stress protectant
- Aids in carbon storage and transport
- Can be utilized as a food ingredient and pharmaceutical excipient
- No toxic effects on Chinese hamster ovary (CHO) cells at 5000 μg/mL
Medchemexpress LLC Egcg octaacetate | 148707-39-5 | 1 MG
EGCG Octaacetate (AcEGCG) is a proagent of Green tea epigallocatechin-3-gallate (EGCG). It works by down-regulating PI3K/Akt/NFκB phosphorylation and p65 acetylation, offering a range of biological activities including antibacterial effects.
- Decreases proinflammatory mediator levels.
- Functions as an antibacterial compound for gram-positive bacteria (GPB) and gram-negative bacteria (GNB).
- Exhibits antioxidant, anti-angiogenesis, anti-inflammatory, and antitumor properties.
- Reduces colitis-driven colon cancer in mouse models.
Medchemexpress LLC α-Lactose (α-D-Lactose) | 14641-93-1 | 5 G
α-Lactose (α-D-Lactose) is the primary sugar found in milk, existing in two anomeric forms, α and β. The α form typically crystallizes as a monohydrate. This disaccharide plays a crucial role as a fundamental nutrient and serves as the main substrate in fermentation processes for products like yogurt and kefir.
- Purity of 98.0%
- Molecular weight: 342.30
- Chemical formula: C12H22O11
- Appearance: solid
- Color: white to light yellow
- Structure classification: saccharides, polysaccharides
- Initial source: animals (milk of humans and domestic animals)
Medchemexpress LLC Prostaglandin D Synthase Antibody (YA1739) | 100 UL
Prostaglandin D Synthase Antibody (YA1739) is a rabbit-derived, non-conjugated IgG monoclonal antibody that targets Prostaglandin D Synthase. This protein acts as a glutathione-independent prostaglandin D synthase, converting prostaglandin H2 (PGH2) to prostaglandin D2 (PGD2). PGD2 plays various roles as a neuromodulator, a trophic factor in the central nervous system, and is involved in smooth muscle contraction/relaxation, as well as being a potent inhibitor of platelet aggregation. The related gene is primarily expressed in the brain, with studies suggesting its involvement in regulating non-rapid eye movement sleep.
- Supplied in 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
- Stored at -20°C for 1 year, avoid repeated freeze/thaw cycles
- Liquid appearance
- Reactivity with human, mouse, and rat
- Applications: WB, IHC-P, IHC-F, ICC/IF
Pfanstiehl Inc Sucrose, USP-NF, EP, BP, JP, ChP High Purity, Low Endotoxin, Low Metals (Beet Derived) (S-124-2-MC) 5kg pack GMP, Multi-Compendial CAS: 57-50-1 Injectable Excipient Grade
Pfanstiehl Sucrose (Beet Derived) - High Purity, Low Endotoxin, Low Metals is a multi-compendial stabilizer of proteins, lipids, and carbohydrates in biologic therapeutics. Used throughout formulation and freeze/thaw cycles, it ensures stability and efficacy in biopharmaceutical applications. Manufactured in the USA under ICH-Q7 cGMP conditions, Pfanstiehl Sucrose meets parenteral (injectable) excipient grade standards, making it ideal for biologic and vaccine formulations. It is also widely used in cryopreservation media to protect cell membranes and enhance cell recovery for bioproduction and cell therapy. Pfanstiehl Brand Sucrose is multi-compendial and available as USP-NF (National Formulary), EP (Ph. Eur.) (European Pharmacopoeia), JP (Japanese Pharmacopoeia), and ChP (Chinese Pharmacopoeia) Compendial Sucrose, GMP Sucrose, cGMP sucrose, sucrose excipient, injectable sucrose, pharmaceutical sucrose, U.S.P. sucrose .
Cayman Chemical n-Decyl-β-D-maltoside, Purity: ≥95%, CAS: 82494-09-5, 5 g
A nonionic surfactant; commonly used to solubilize and stabilize membrane proteins; CMC = 1.8 mM; has been used in the expression of functional recombinant GPCRs
Medchemexpress LLC D-3263 hydrochloride | 1008763-54-9 | 98.12% | 409.95 | 100 MG
D-3263 hydrochloride is an enteric-coated, orally bioavailable transient receptor potential melastatin member 8 (TRPM8) agonist. It binds to and activates TRPM8, which may lead to an increase in calcium and sodium entry, disruption of calcium and sodium homeostasis, and induction of cell death in TRPM8-expressing tumor cells. D-3263 hydrochloride may also decrease dihydrotestosterone (DHT) levels, potentially contributing to its inhibitory effects on prostate cancer and benign prostatic hyperplasia (BPH).
- Binds to and activates TRPM8.
- Increases calcium and sodium entry into cells.
- Disrupts calcium and sodium homeostasis.
- Induces cell death in TRPM8-expressing tumor cells.
- Decreases dihydrotestosterone (DHT) levels.
- Inhibits prostate cancer and benign prostatic hyperplasia (BPH).
Medchemexpress LLC (D-Ser1)-ACTH (1-24) (human, bovine, mouse, ovine, porcine, rabbit, rat) | 18067-65-7 | >99.9% | 2933.44 | 5 MG
(D-Ser1)-ACTH (1-24) is an adrenocorticotropic hormone (ACTH) analogue. It requires specific storage conditions to maintain stability.
- Suitable for sealed storage, away from moisture.
- Powder can be stored at -80°C for 2 years or -20°C for 1 year.
- In solvent, it can be stored at -80°C for 6 months or -20°C for 1 month.
Apexbio Technology LLC Trehalose(Synonyms: Mycose, α,α-Trehalose, alpha-D-glucopyranosyl-alpha-D-glucopyranoside), 500mg, CAS: 99-20-7.
Trehalose (CAS 99-20-7) isolated from Saccharomyces cerevisiae is a non-reducing disaccharide composed of two -glucose units connected by an -1 1-glucosidic linkage It enhances cellular resistance to stress factors such as dehydration and cryopreservation however mammalian cells require intracellular presence of trehalose which is limited by low membrane permeability due to its hydrophilic non-ionic nature Derivatization strategies (e g acetylation) to increase membrane traversal may enable the application of trehalose in biopreservation and cytoprotection research