Carbohydrates
Medchemexpress LLC D-GsMTx4 | 1209500-46-8 | 99.4% | 4095.84 | 500 UG
D-GsMTx4 is a spider peptide and the D enantiomer of GsMTx4. It functions as an inhibitor of the mechanosensitive ion channel Piezo2. It also inhibits [Ca2+]i elevation and the mTOR and PI3K-Akt signaling pathways. This compound has been used in research related to mechanical stress, chronic pain, and idiopathic pulmonary fibrosis, and inhibits mechanical allodynia and thermal hyperalgesia.
- Inhibits mechanosensitive ion channel Piezo2
- Decreases phosphorylation levels of proteins in mTOR and PI3K-Akt signaling pathways
- Inhibits mechanical stimulation-evoked calcium increases
- Significantly inhibits mechanical allodynia and thermal hyperalgesia
- Used in research for mechanical stress, chronic pain, and idiopathic pulmonary fibrosis
Apexbio Technology LLC ISRIB (trans-isomer) 1597403-47-8 25mg
ISRIB (trans-isomer) (CAS 1597403-47-8) is a small molecule inhibitor of the integrated stress response (ISR) ISR activation involves the phosphorylation of eukaryotic initiation factor 2 (eIF2 ) by stress-sensitive kinases leading to reduced global protein synthesis and enhanced translation of select mRNAs ISRIB counteracts ISR signaling by reversing the translational suppression induced by phosphorylated eIF2 inhibiting production of ATF4 protein decreasing stress granule assembly and promoting polyribosome formation during endoplasmic reticulum (ER) stress ISRIB stabilizes and activates eIF2B by facilitating its dimerization Rodent studies demonstrate ISRIB s capacity to enhance hippocampal-dependent spatial and fear-related learning and memory highlighting its utility in neuroscience research
Medchemexpress LLC D-(+)-Trehalose | 99-20-7 | 342.30 | 500 MG
D-(+)-Trehalose is an orally active disaccharide that exhibits anti-desiccant and cryopreservative activities. It functions as an osmolyte and stress protectant, aiding in carbon storage and transport. It can be utilized as a food ingredient and a pharmaceutical excipient.
- Orally active disaccharide
- Exhibits anti-desiccant and cryopreservative activities
- Functions as an osmolyte and stress protectant
- Aids in carbon storage and transport
- Can be utilized as a food ingredient and pharmaceutical excipient
- No toxic effects on Chinese hamster ovary (CHO) cells at 5000 μg/mL
Apexbio Technology LLC Trehalose(Synonyms: Mycose, α,α-Trehalose, alpha-D-glucopyranosyl-alpha-D-glucopyranoside), 500mg, CAS: 99-20-7.
Trehalose (CAS 99-20-7) isolated from Saccharomyces cerevisiae is a non-reducing disaccharide composed of two -glucose units connected by an -1 1-glucosidic linkage It enhances cellular resistance to stress factors such as dehydration and cryopreservation however mammalian cells require intracellular presence of trehalose which is limited by low membrane permeability due to its hydrophilic non-ionic nature Derivatization strategies (e g acetylation) to increase membrane traversal may enable the application of trehalose in biopreservation and cytoprotection research
Medchemexpress LLC VEGF-D Rat HEK293 1mg
VEGF-D a growth factor stimulates proliferation migration and vessel permeability It is crucial for vascular development and maintenance of lymphatic endothelium VEGF-D binds and activates VEGFR-3 initiating essential signaling pathways Structurally it forms a non-covalent homodimer playing an intricate role in vascular processes VEGF-D Protein Rat (HEK293 Fc) is the recombinant rat-derived VEGF-D protein expressed by HEK293 with N-hFc labeled tag
![eMolecules 129572-48-1 | 5-Bromo-4-chloro-3-indolyl N-acetyl-beta-D-galactosaminide | Apollo Scientific | MFCD00083260 | 449.680 | C16H18BrClN2O6 | 0.000 | CC(=O)N[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@H]1Oc1c[nH]c2ccc(Br)c(Cl)c12 | 1g | 562458735](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502151923.JPG-250.jpg)
eMolecules 129572-48-1 | 5-Bromo-4-chloro-3-indolyl N-acetyl-beta-D-galactosaminide | Apollo Scientific | MFCD00083260 | 449.680 | C16H18BrClN2O6 | 0.000 | CC(=O)N[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@H]1Oc1c[nH]c2ccc(Br)c(Cl)c12 | 1g | 562458735
5-Bromo-4-chloro-3-indolyl N-acetyl-beta-D-galactosaminide | Apollo Scientific | 129572-48-1 | MFCD00083260 | 449.680 | C16H18BrClN2O6 | 0.000 | CC(=O)N[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@H]1Oc1c[nH]c2ccc(Br)c(Cl)c12 | 1g | 562458735
Medchemexpress LLC (D)-PPA 1 TFA | 99.3% | 1669.67 | 5 MG
(D)-PPA 1 TFA is a hydrolysis-resistant d-peptide antagonist that serves as a potent PD-1/PD-L1 inhibitor. It binds to PD-1 with an affinity of 0.51 μM, demonstrating both in vitro and in vivo efficacy.
- Hydrolysis-resistant d-peptide antagonist
- Potent PD-1/PD-L1 inhibitor
- Binds to PD-1 with an affinity of 0.51 μM
- Blocks the interaction between PD-1/PD-L1
- Inhibits CT26 tumor growth in mice
- Targets tumor tissue in CT26-tumor-bearing mice
Apexbio Technology LLC Methyl α-D-mannopyranoside 617-04-9 25g
Methyl alpha-D-mannopyranoside (CAS 617-04-9) is a small-molecule ligand targeting mannose receptors expressed on macrophages It is designed to bind selectively to these receptors thereby facilitating internalization and intracellular delivery of conjugated therapeutic agents Methyl alpha-D-mannopyranoside exerts its biological activity primarily through specific binding to macrophage mannose receptors enabling targeted transport into macrophages Studies evaluating receptor binding report IC50 values generally ranging from micromolar to millimolar levels depending on experimental conditions and assay methods Based on these pharmacological properties methyl alpha-D-mannopyranoside holds research potential in targeted drug delivery for anti-tubercular therapies
![Medchemexpress LLC 2,5-bis[(morpholin-4-yl)methyl]benzene-1,4-diol | 6616-56-4 | MFCD00087356 | 99.7% | 308.37 g/mol | C16H24N2O4 | 100 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000246935.png-250.jpg)
Medchemexpress LLC 2,5-bis[(morpholin-4-yl)methyl]benzene-1,4-diol | 6616-56-4 | MFCD00087356 | 99.7% | 308.37 g/mol | C16H24N2O4 | 100 MG
MSX-127 is a small-molecule CXCR4 antagonist used in research to study CXCR4-mediated signaling and cancer metastasis. It is a di-morpholinomethyl-substituted hydroquinone (C16H24N2O4; MW 308.37 g/mol) supplied as a high-purity solid and commonly prepared in DMSO for in vitro assays.
- Potent CXCR4 antagonist for research applications
- Reported to inhibit cancer metastasis in preclinical studies
- High purity (≈99.7%) suitable for biochemical and cell-based assays
- Provided as a powder, with solution formulations available in DMSO
- Chemical formula C16H24N2O4; molecular weight 308.37 g/mol
Medchemexpress LLC D-Lactose monohydrate (Standard) | 64044-51-5 | 99.5% | 500 MG
D-Lactose monohydrate is an analytical standard intended for research and analytical applications. This sugar can be utilized by most bacteria and promotes the growth of tobacco B6S3 tumor tissue, making it suitable for research into plant tumor growth mechanisms and bacterial sugar utilization.
- Analytical and reference standard supplied assay
- Used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS
- Appearance: solid
- Color: white to off-white
- Structure classification: saccharides, polysaccharides
- Initial source: endogenous metabolite
- Suitable for research and analytical applications
- Provides a reference standard for various analytical experiments
Medchemexpress LLC Benzenepropanol, β-amino-, (βR)- | 5267-64-1 | MFCD00064298 | 98.8% | 151.21 g/mol | C9H13NO | 100 G
D-Penylalaninol is the D-enantiomer of phenylalaninol, a chiral amino alcohol used as a research-grade biochemical reagent and synthetic building block. The compound is an organic solid with formula C9H13NO, molecular weight 151.21 g/mol, and CAS 5267-64-1; lot-specific HPLC purity is provided on the certificate of analysis.
Medchemexpress LLC SP-D Rhesus Macaque 50ug | 50ug
The SP-D protein plays a critical role in the lung s defense mechanisms against inhaled microorganisms organic antigens and toxins This multifunctional protein interacts with a variety of compounds including bacterial lipopolysaccharides oligosaccharides and fatty acids to modulate leukocyte activity in immune responses SP-D Protein Rhesus Macaque (HEK293 His) is the recombinant Rhesus Macaque-derived SP-D protein expressed by HEK293 with C-His labeled tag
Medchemexpress LLC Oxiconazole nitrate | 64211-46-7 | MFCD01727545 | 98.0% | 492.14 | C18H14Cl4N4O4 | 10 MG
Oxiconazole nitrate is an imidazole-class antifungal research compound supplied as a high-purity solid for laboratory use. The nitrate salt of oxiconazole shows broad-spectrum activity against dermatophytes and common fungal pathogens and is used in biochemical screening and in vitro antifungal assays.
- Chemical formula C18H14Cl4N4O4.
- CAS number 64211-46-7.
- Molecular weight 492.14 g/mol.
- Reported purity 98.0%.
- Suitable for in vitro antifungal studies and screening assays.
- Available as a 10 mg solid for small-scale research use.
![eMolecules 1010128-58-1 | 3-(1H-2-INDOLYL)-4-(4-METHOXYPHENYL)-1-METHYL-1H-2-QUINOLINONE | AstaTech | MFCD11501397 | 380.447 | C25H20N2O2 | 97.000 | COc1ccc(cc1)-c1c(-c2cc3ccccc3[nH]2)c(=O)n(C)c2ccccc12 | 1g | 112527535](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502171736.JPG-250.jpg)
eMolecules 1010128-58-1 | 3-(1H-2-INDOLYL)-4-(4-METHOXYPHENYL)-1-METHYL-1H-2-QUINOLINONE | AstaTech | MFCD11501397 | 380.447 | C25H20N2O2 | 97.000 | COc1ccc(cc1)-c1c(-c2cc3ccccc3[nH]2)c(=O)n(C)c2ccccc12 | 1g | 112527535
3-(1H-2-INDOLYL)-4-(4-METHOXYPHENYL)-1-METHYL-1H-2-QUINOLINONE | AstaTech | 1010128-58-1 | MFCD11501397 | 380.447 | C25H20N2O2 | 97.000 | COc1ccc(cc1)-c1c(-c2cc3ccccc3[nH]2)c(=O)n(C)c2ccccc12 | 1g | 112527535