Sucrose octasulfate sodium, a sulfated oligosaccharide derivative, acts as a matrix metalloproteinase (MMP) inhibitor. It stimulates the release of somatostatin-like immunoreactivity (SLI) from the stomach, directly affecting D cells in the gastric mucosa, which contributes to its ulcer-healing effect. This compound can be used as a pharmaceutical excipient, significantly improving wound closure in diabetic foot ulcers (nerve ischemia) and venous leg ulcers, and is also used in chronic wound healing studies.
- MMP inhibitor
- Stimulates the release of somatostatin-like immunoreactivity (SLI) from the stomach
- Exerts ulcer-healing effects by releasing endogenous gastric somatostatin
- Can be used as a pharmaceutical excipient
- Significantly improves wound closure in diabetic foot ulcers and venous leg ulcers
- Useful for chronic wound healing studies